Search results for "Transmission"
showing 10 items of 2080 documents
Drought-related cholera outbreaks in Africa and the implications for climate change: a narrative review.
2021
ABSTRACT Africa has historically seen several periods of prolonged and extreme droughts across the continent, causing food insecurity, exacerbating social inequity and frequent mortality. A known consequence of droughts and their associated risk factors are infectious disease outbreaks, which are worsened by malnutrition, poor access to water, sanitation and hygiene and population displacement. Cholera is a potential causative agent of such outbreaks. Africa has the highest global cholera burden, several drought-prone regions and high levels of inequity. Despite this, research on cholera and drought in Africa is lacking. Here, we review available research on drought-related cholera outbreak…
Silk fibroin scaffolds enhance cell commitment of adult rat cardiac progenitor cells.
2015
The use of three-dimensional (3D) cultures may induce cardiac progenitor cells to synthesize their own extracellular matrix (ECM) and sarcomeric proteins to initiate cardiac differentiation. 3D cultures grown on synthetic scaffolds may favour the implantation and survival of stem cells for cell therapy when pharmacological therapies are not efficient in curing cardiovascular diseases and when organ transplantation remains the only treatment able to rescue the patient’s life. Silk fibroin-based scaffolds may be used to increase cell affinity to biomaterials and may be chemically modified to improve cell adhesion. In the present study, porous, partially orientated and electrospun nanometric n…
Targeting Homer genes using adeno-associated viral vector: lessons learned from behavioural and neurochemical studies.
2008
Over a decade of in-vitro data support a critical role for members of the Homer family of postsynaptic scaffolding proteins in regulating the functional architecture of glutamate synapses. Earlier studies of Homer knockout mice indicated a necessary role for Homer gene products in normal mesocorticolimbic glutamate transmission and behaviours associated therewith. The advent of adeno-associated viral vectors carrying cDNA for, or short hairpin RNA against, specific Homer isoforms enabled the site-directed targeting of Homers to neurons in the brain. This approach has allowed our groups to address developmental issues associated with conventional knockout mice, to confirm active roles for di…
Evidence for synergistic and complementary roles of Bassoon and darkness in organizing the ribbon synapse
2012
Abstract Ribbon synapses are tonically active high-throughput synapses. The performance of the ribbon synapse is accomplished by a specialization of the cytomatrix at the active zone (CAZ) referred to as the synaptic ribbon (SR). Progress in our understanding of the structure–function relationship at the ribbon synapse has come from observations that, in photoreceptors lacking a full-size scaffolding protein Bassoon ( Bsn Δ Ex 4 / 5 ), dissociation of SRs coincides with perturbed signal transfer. The aim of the present study has been to elaborate the role of Bassoon as a structural organizer of the ribbon synapse and to differentiate it with regard to the ambient lighting conditions. The ul…
Endothelial cell colonization and angiogenic potential of combined nano- and micro-fibrous scaffolds for bone tissue engineering
2008
Presently the majority of tissue engineering approaches aimed at regenerating bone relies only on postimplantation vascularization. Strategies that include seeding endothelial cells (ECs) on biomaterials and promoting their adhesion, migration and functionality might be a solution for the formation of vascularized bone. Nano/micro-fiber-combined scaffolds have an innovative structure, inspired by extracellular matrix (ECM) that combines a nano-network, aimed to promote cell adhesion, with a micro-fiber mesh that provides the mechanical support. In this work we addressed the influence of this nano-network on growth pattern, morphology, inflammatory expression profile, expression of structura…
Identification of Chinese fresh-water pearls using MN2+ activated cathodoluminescence
2000
Fresh-water tissue graft-cultured pearls from China were investigated using hot cathode and cold cathode cathodoluminescence microscopes. Supplementary investigations were done using X-radiography, a Scanning Electron Microscope, an optical microscope, and an Atomic Force Microscope (AFM). The results were compared with those of natural fresh-water pearls from the Mississippi river. Thin sections of fresh-water natural pearls from the Mississippi river could be distinguished from those of fresh-water tissue graft cultured pearls from China using a hot cathode cathodoluminescence microscope according to the distribution of Mn2+ as follows: (1) Fresh-water tissue graft cultured pearls from Ch…
Reaction-diffusion on dynamic inhibition areas: A bio-inspired link scheduling algorithm
2014
We present the Dynamic Inhibition Areas Reaction-Diffusion (DIA-RD) algorithm, a distributed medium access control protocol that globally maximizes the spatial reusability (number of simultaneous transmissions per unit area) of wireless sensor networks. This algorithm is able, in consequence, to minimize the number of time slots needed to schedule the set of demanded links, making it very efficient to solve the Shortest Link Schedule problem. DIA-RD combines accurate interference management, provided by the use of dynamic inhibition areas based on the physical interference model; and global intelligent behavior, provided by the bio-inspired technique known as Reaction-Diffusion. This techni…
Functional design of power-split CVTs: An uncoupled hierarchical optimized model
2017
Abstract This paper provides a new model for the preliminary design of compound power-split CVTs. Unlike the existing models, the presented method allows the engineers to prioritize functionality and efficiency of the transmission, while delaying the choice of the involved gear sets’ layout as long as possible. The design approach follows a specific priority order, and each step deals with one particular issue, without mutual interference. A smart design-chart eases the assessment and the comparison of the only eligible alternatives, and eventually leads to a final feasible constructive scheme, which can be an excellent concept for further optimization and implementation. Moreover, the mode…
Reducing Overhearing Energy in Wake-Up Radio-Enabled WPANs: Scheme and Performance
2018
Wake-up Radio (WuR)-enabled wireless personal area networks (WPANs) are more popular over conventional WPANs thanks to WuR's on-demand transmission feature and overwhelming energy consumption superiority. In a WuRenabled WPAN, overhearing occurs when a wake-up receiver decodes and validates the address of a wake-up call which is not intended to it. However, such overhearing consumes a portion of the required reception energy for unintended nodes. To diminish overhearing thus conserve total reception energy in a network, we propose a bit-by-bit address decoding (BBAD) scheme and compare it with another addressing scheme for WuR that uses a micro-controller unit to decode and match the whole …
Receiver-Initiated Data Collection in Wake-Up Radio Enabled mIoT Networks: Achieving Collision-Free Transmissions by Hashing and Partitioning
2021
To achieve ultra-low energy consumption and decade-long battery lifetime for Internet of Things (IoT) networks, wake-up radio (WuR) appears as an eminent solution. While keeping devices in deep sleep for most of the time, a WuR enabled IoT device can be woken up for data transmission at any time by a wake-up call (WuC). However, collisions happen among WuCs for transmitter-initiated data reporting and among data packets for receiver-initiated data collection . In this article, we propose three novel hashing-based schemes in order to achieve collision-free data transmissions for receiver-initiated data collection. We consider first a simple scenario where all devices in a region of interest …