Search results for "Transport protein"

showing 2 items of 362 documents

CYGD: the Comprehensive Yeast Genome Database.

2005

The comprehensive resource is available under http://mips.gsf.de/genre/proj/yeast/.; International audience; The Comprehensive Yeast Genome Database (CYGD) compiles a comprehensive data resource for information on the cellular functions of the yeast Saccharomyces cerevisiae and related species, chosen as the best understood model organism for eukaryotes. The database serves as a common resource generated by a European consortium, going beyond the provision of sequence information and functional annotations on individual genes and proteins. In addition, it provides information on the physical and functional interactions among proteins as well as other genetic elements. These cellular network…

ved/biology.organism_classification_rank.speciesSACCHAROMYCES CEREVISIAE GENOME;COMPREHENSIVE YEAST GENOME DATABASE;CYGD;PROTEIN INTERACTION;EUROPEAN CONSORTIUM;SEQUENCE INFORMATION;YEAST GENOME;SEQUENCED EUKARYOTIC GENOMEcomputer.software_genreGenomeSaccharomycesUser-Computer InterfaceSequence Analysis ProteinDatabases GeneticYEAST GENOME[INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM]0303 health sciences[SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]biologyDatabase030302 biochemistry & molecular biologyEUROPEAN CONSORTIUMArticlesGenomicsCYGD[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]PROTEIN INTERACTIONSEQUENCED EUKARYOTIC GENOMEnucleic acidsCOMPREHENSIVE YEAST GENOME DATABASEBio-informatiqueGenome FungalSEQUENCE INFORMATIONSaccharomyces cerevisiae ProteinsBioinformaticsSaccharomyces cerevisiae610Saccharomyces cerevisiaeGenètica molecularSACCHAROMYCES CEREVISIAE GENOMESaccharomyces03 medical and health sciencesAnnotationGeneticsSIMAPModel organismGene030304 developmental biologyBinding Sitesved/biologyMembrane ProteinsMembrane Transport Proteinsbiology.organism_classificationYeast[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]computerSDV:BIBSTranscription Factors
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Impact of VP1-Specific Protein Sequence Motifs on Adeno-Associated Virus Type 2 Intracellular Trafficking and Nuclear Entry

2012

ABSTRACT Adeno-associated virus type 2 (AAV2) has gained much interest as a gene delivery vector. A hallmark of AAV2-mediated gene transfer is an intracellular conformational change of the virus capsid, leading to the exposure of infection-relevant protein domains. These protein domains, which are located on the N-terminal portion of the structural proteins VP1 and VP2, include a catalytic phospholipase A 2 domain and three clusters of basic amino acids. We have identified additional protein sequence motifs located on the VP1/2 N terminus that also proved to be obligatory for virus infectivity. These motifs include signals that are known to be involved in protein interaction, endosomal sort…

virusesImmunologyProtein domainAmino Acid MotifsMolecular Sequence DataSequence alignmentBiologyMicrobiologyVirusCell LineParvoviridae InfectionsVirologyHumansAmino Acid SequenceAdeno-Associated Virus Type 2Peptide sequenceCell NucleusDependovirusMolecular biologyTransport proteinCell biologyVirus-Cell InteractionsProtein TransportCapsidInsect ScienceCapsid ProteinsSequence motifSequence Alignment
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