Search results for "Treatment effect"
showing 10 items of 29 documents
Interactions, spillovers de connaissance et croissance des villes européennes. Faut-il préférer la géographie, le climat institutionnel ou les réseau…
2013
Knowledge spillovers within urban economies are also sources of spillovers between cities. We examine how knowledge spillovers influenced the economic growth of 82 European metropolises over the 1990-2005 period. We model knowledge spillovers between cities on the basis of five specific interaction patterns based on geography, networks of multinational firms in advanced services, institutional climate and two combinations of these factors. Spatial models are estimated to detail the effects of growth factors in terms of spillovers and externalities. We show that spillovers are local rather than global and that interactions among cities accelerate the convergence process based on gross value …
Productivity analysis of Latvian companies using ORBIS database
2021
International audience; This research study uses ORBIS microdata at the company level to analyse productivity of 167 thousand economically active Latvian companies over 2011-2018. The aim of the study is twofold-to find factors consistently associated with productivity at the company level; and to recommend possible criteria for companies to receive a state support (from the view of enhancing aggregate productivity in the long term). Our research results show that productivity of Latvian companies is positively related to their size, age, as well as location closer to Riga and other big cities. However, there is a substantial within-group variation in productivity between companies. Multiva…
NEIGHBORHOOD EFFECTS IN SPATIAL HOUSING VALUE MODELS. THE CASE OF THE METROPOLITAN AREA OF PARIS (1999)
2009
In hedonic housing models, the spatial dimension of housing values are traditionally processed by the impact of neighborhood variables and accessibility variables. In this paper we show that spatial effects might remain once neighborhood effects and accessibility have been controlled for. We notably stress on three sides of neighborhood effects: social capital, social status and social externalities and consider the accessibility to the primary economic center as describing the urban spatial trend. Using spatial econometrics specifications of the hedonic equation, we estimate whether spatial effects impact the housing values. Our empirical case concerns the Metropolitan Area (MA) of Paris i…
The Vegf Pathway in Patients with Pancreatic Neuroendocrine Tumors: Efficacy of Everolimus by Baseline Marker Level, and Prognostic and Predictive Ef…
2012
ABSTRACT Background RADIANT-3 was a phase III study investigating the effect of the mammalian target of rapamycin inhibitor everolimus on progression-free survival (PFS) in patients with advanced pancreatic neuroendocrine tumors (pNET; Yao et al, NEJM, 2011). Everolimus significantly improved PFS compared with placebo (11 vs 4.6 months, P Methods Baseline plasma levels of VEGF-A, PlGF, sVEGFR1, and sVEGFR2 were determined by ELISA using multiplexed MSD platform. The optimal cutoffs for these markers were explored using the “survival tree analysis” method. Interaction of treatment and baseline marker status ( Results PFS was significantly improved to a similar extent in patients receiving e…
Responding to the Spiritual Needs of Palliative Care Patients: A Randomized Controlled Trial to Test the Effectiveness of the Kibo Therapeutic Interv…
2020
Context The WHO recognizes the need to attend to patients' spiritual needs as being fundamental to comprehensive and high-quality end-of-life care. Spiritual needs must be attended since the resolution of biological and psychosocial issues is insufficient to reduce patients' suffering. Associations have been found between spiritual needs and other variables of importance for patients in palliative care. Despite the consensus that exists regarding the importance of assessing and attending to spiritual needs, professionals encounter many difficulties in attempting to do so. Objectives Our study aims to demonstrate the benefits that the KIBO therapeutic interview in palliative care patients ca…
Partially time invariant panel data regression
2023
When dealing with panel data, considering the variation over time of the variable of interest allows to get rid of potential individual effects. Even though the outcome variable has a continuous distribution, its variation over time can be equal to zero with a strictly positive probability and thus its distribution is a mixture of a mass at zero and a continuous distribution. We introduce a parametric statistical model based on conditional mixtures, build estimators for the parameters related to the conditional probability of no variation and to the conditional expectation related to the continuous part of the distribution and derive their asymptotic consistency and normality under a specif…
Response und Remission in der Psychotherapieforschung
2010
Treatment effects of psychotherapy are usually studied using analysis of mean differences, tests of significance and effect size measures. These strategies, however, do not answer the question of how large the proportion of patients is who responded to treatment or who even reached remission. This article compares 2 competing methods of response and remission analysis: The Reliable Change Index (RCI) according to Jacobson et al. and the method of percent symptom reduction (PSR). We applied both methods using a sample of 338 patients with DSM-IV major depressive disorder. A pre-post treatment effect of Cohen's d=1,16 (intention-to-treat) resulted for the Beck Depression Inventory (BDI), corr…
Effect of treatment on sex offenders' recidivism: a meta-analysis
2017
Este meta-análisis tiene por objetivo medir el efecto del trata- miento en delincuentes sexuales. Tras una revisión sistemática de la litera- tura reciente, fueron seleccionados diecisiete estudios, contando con una muestra total de 6,681 delincuentes sexuales. Las tasas de reincidencia se- xual (13.12% vs. 17.94%), violenta –incluyendo la sexual– (25.5% vs. 29.1%) y general –cualquier tipo de reincidencia– (46.53% vs. 52.41%) de los delincuentes tratados fueron inferiores a las de los grupos control. Se evidenció la eficacia del tratamiento en la reducción de las tasas de reinci- dencia sexual (OR = .69; p< .05) y general (OR = .66; p < .05) de los sujetos tratados, pero no en las tasas de…
Interindividual Differences in Treatment Effects based on Structural Equation Models with Latent Variables: An EffectLiteR Tutorial
2019
The investigation of interindividual differences in the effects of a treatment is challenging, because many constructs-of-interest in psychological research such as depression or anxiety are latent variables and modeling heterogeneity in treatment effects requires interactions and potentially nonlinear relationships. In this paper, we present a tutorial of the EffectLiteR approach (Mayer, Dietzfelbinger, Rosseel, &amp; Steyer, 2016) that allows for estimating individual treatment effects based on latent variable models. We describe step by step how to apply the approach using the EffectLiteR software package with data from the multicenter randomized controlled trial of the Social Phobia…
Marginal hazard ratio estimates in joint frailty models for heart failure trials
2019
Abstract This work is motivated by clinical trials in chronic heart failure disease, where treatment has effects both on morbidity (assessed as recurrent non‐fatal hospitalisations) and on mortality (assessed as cardiovascular death, CV death). Recently, a joint frailty proportional hazards model has been proposed for these kind of efficacy outcomes to account for a potential association between the risk rates for hospital admissions and CV death. However, more often clinical trial results are presented by treatment effect estimates that have been derived from marginal proportional hazards models, that is, a Cox model for mortality and an Andersen–Gill model for recurrent hospitalisations. …