Search results for "Treatments"
showing 10 items of 144 documents
The CRATI project: New insights on the consolidation of saltweathered stone and the case study of San Domenico Church in Cosenza (South Calabria, Ita…
2019
This paper presents the results of a laboratory experimentation carried out on stone materials in the framework of the CRATI project (Knowledge and Restoration through Advanced Integrated Technologies) aimed at testing new products with consolidating properties by means of an integrated methodological approach. After the preliminary characterization of stone materials collected in the pilot site, the second stage of the activities within the project were focused on the formulation and testing of products for the conservation of the same materials against decay, especially salt crystallization, one of the most aggressive and common degrading processes. The San Domenico Church, located in the…
Induced Modification of Flexural Toughness of Natural Hydraulic Lime Based Mortars by Addition of Giant Reed Fibers
2020
Abstract Nowadays, there is a growing need to reduce the environmental impact generated by the use of inorganic materials for building applications. The aim of this work is to investigate the bio-lime based mortar flexural toughness improvement due to the addition of common reed fibers (Arundo donax L.) in order to evaluate their possible application as ductile eco-compatible prefabricated bricks or laying and joint mortars for masonry. Different sets of specimens were tested by varying the fiber weight content and the fiber length. Moreover, chemical treatments with Linseed Oil and Polyethylene glycol (PEG) were performed to improve the physical and mechanical properties of the fibers as w…
Mechanical and metallurgical effects of in process cooling during friction stir welding of AA7075-T6 butt joints
2010
This paper presents the results of a combined experimental and numerical investigation focused on the effects of an in process water cooling treatment aimed at improving the final quality of friction stir welded butt joints in terms of mechanical resistance and metallurgy of the processed material. Micro and macro observations, together with the evolution of an already developed finite element tool, have been used to analyze specimens obtained under different process conditions. Water cooling was found to enhance joint strength, reducing the material softening usually observed in the thermo-mechanically affected zone area, with no detrimental effect on nugget integrity.
Microstructural and tribological study of Nd:YAG laser treated titanium plates.
2008
Abstract In this work, the fretting behaviour of pure Ti plates laser treated with a Nd:YAG pulsed laser was compared to that of untreated Ti plates. Fretting tests were done at room temperature without lubrication. The contact geometry was a cylinder (bearing steel) on a plane. The evolution of both the ratio, μ = Q / P , between the normal and the tangential forces, and the Fouvry's energy criterion ( A ) were recorded as a function of the number of fretting cycles, N . Energy dispersive spectrometry and micro-Raman spectroscopy were used to analyse the fretting scars. The oxidized layer formed by the laser treatment displayed a mixed slip regime as a function of N , and a smaller frettin…
Role of neurorehabilitative treatment using transcranial magnetic stimulation in disorders of consciousness
2021
Disorders of consciousness (DOC) result from brain injuries that cause functional changes in vigilance, awareness and behaviour. It is important to correctly diagnose DOC so that the most appropriate rehabilitation treatments can be initiated. Several studies in DOC patients have demonstrated that repetitive transcranial magnetic stimulation (rTMS) has an important role to play in the recovery of consciousness as highlighted by monitoring clinical scale scores. Although studies indicate that rTMS can be used to aid recovery, it is not combined with other rehabilitative cognitive treatments. As of December 2018, there have been no studies published that combined DOC cognitive rehabilitation…
Different approaches for the solar photocatalytic removal of micro-contaminants from aqueous environment: Titania vs. hybrid magnetic iron oxides
2019
Abstract This work reports on the light-induced heterogeneous photodegradation of four micro-contaminants (MCs): Carbamazepine (C), Flumequine (F), Ibuprofen (I), and Sulfamethoxazole (S), using two different heterogeneous advanced oxidation processes. The first one is the semiconductor photocatalysis, run in the presence of the suspension of a home prepared TiO2 (TiO2 HP); the second one is an heterogeneous photo-Fenton process run in the presence of a hybrid magnetic nanomaterial (MB3) with an iron oxides core and an organic shell made of bio-based substances (BBS) isolated from urban biowaste. The two materials work upon two different mechanisms and were already tested (and the action me…
Understanding the Effects of High Pressure on Bacterial Spores Using Synchrotron Infrared Spectroscopy
2020
International audience; Bacterial spores are extremely resistant life-forms that play an important role in food spoilage and foodborne disease. The return of spores to a vegetative cell state is a three-step process, these being activation, germination, and emergence. High-pressure (HP) processing is known to induce germination in part of the spore population and even to inactivate a high number of Bacillus spores when combined with other mild treatments such as the addition of nisin. The aim of the present work was to investigate the mechanisms involved in the sensitization of spores to nisin following HP treatment at ambient temperature or with moderate heating leading to a heterogeneous …
Emerging Therapeutic Strategies for Traumatic Spinal Cord Injury
2020
Spinal cord injury (SCI) is a debilitating neurologic condition with tremendous socioeconomic impact on affected individuals and the health care system. The treatment of SCI principally includes surgical treatment and marginal pharmacologic and rehabilitation therapies targeting secondary events with minor clinical improvements. This unsuccessful result mainly reflects the complexity of SCI pathophysiology and the diverse biochemical and physiologic changes that occur in the injured spinal cord. Once the nervous system is injured, cascades of cellular and molecular events are triggered at varying times. Although the cascade of tissue reactions and cell injury develops over a period of days …
Nipple-sparing mastectomy and breast reconstruction with a deep inferior epigastric perforator flap using thoracodorsal recipient vessels and a low l…
2018
Background Nipple-sparing mastectomy poses challenges in providing esthetically-pleasing immediate autologous breast reconstruction. This study was to investigate the outcomes of nipple-sparing mastectomy with breast reconstruction using free abdominal flaps between two different recipient sites. Methods Between 2010 and 2016, 79 patients who underwent nipple-sparing mastectomy with autologous breast reconstruction using thoracodorsal (TD) vessels in 30 cases or internal mammary (IM) vessels in 49 cases were investigated. Demographics, intraoperative findings, complications, and quality of life using Breast-Q questionnaire were compared between two groups. Results All flap survived. There w…
A phase I dose escalation and expansion study of the next generation oral SERD AZD9833 in women with ER-positive, HER2-negative advanced breast cancer
2020
1024 Background: AZD9833 is an oral selective estrogen receptor (ER) antagonist and degrader (SERD) that has shown antitumor efficacy in a range of preclinical models of breast cancer. Methods: SERENA-1 (NCT03616587) is an ongoing Phase 1, open-label study in pre- and post-menopausal women, after ≥1 endocrine therapy and ≤2 prior chemotherapies for ER+ HER2- advanced breast cancer (ABC). The primary objective is to determine the safety and tolerability of AZD9833 once daily (QD), with dose-limiting toxicities (DLTs) in 28d defining the maximum tolerated dose. Secondary objectives include pharmacokinetics and anti-tumor response. Pharmacodynamic (PD) analysis includes ER modulation in paire…