Search results for "Trial"
showing 10 items of 10525 documents
Efficacy of different methods used for dry socket management: A systematic review.
2015
Document publicat també en castellà
Group 1 ITI Consensus Report: The influence of implant length and design and medications on clinical and patient-reported outcomes
2018
The following article: Jung, R.E., Al-Nawas, B., Araujo, M., Avila-Ortiz, G., Barter, S., Brodala, N., ... Windisch, P. (2018). Group 1 ITI Consensus Report: The influence of implant length and design and medications on clinical and patient-reported outcomes. Clinical Oral Implants Research, 29(S16), 69-77, can be accessed at https://doi.org/10.1111/clr.13342. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Objectives: The aim of Working Group 1 was to address the influence of different local (implant length, diameter, and design) and systemic (medications) factors on clinical, radiographic, and patient‐re…
Descriptive study on subjective experience of genetic testing with respect to relationship, family planning and psychosocial wellbeing among women wi…
2021
AbstractBackgroundDue to increased risk of endometrial and ovarian cancer, women belonging to known Lynch Syndrome (LS) families are recommended to undergo germline testing. Current practice in Finland is to offer counselling to women with pathogenic variant and advocate risk-reducing surgery (RRS) after completion of childbirth. The present study aimed to clarify the impacts of positive germline testing on family planning and reproductive decisions of these women, which are relatively unknown.MethodsSeventy-nine carriers of germline MMR gene pathogenic variant (path_MMR)were identified from the Finnish LS Registry as having genetic testing performed before the age of 45 years and not havin…
Evaluation of the Oxiris Membrane in Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support: Study Protocol for a Single Center, Sin…
2021
Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is the rescue treatment proposed to patients with refractory cardiogenic shock. The VA-ECMO implantation promotes inflammation and ischemia-reperfusion injuries through the VA-ECMO flow, causing digestive mucosa barrier disrupture and inducing translocation of bacterial wall components—Lipopolysaccharides (LPS) with further inflammation and circulatory impairment. LPS is a well-studied surrogate indicator of bacterial translocation. Oxiris membrane is a promising and well-tolerated device that can specifically remove LPS. The main study aim is to compare the LPS elimination capacity of Oxiris membrane vs. a non-absorban…
Mid- to Long-Term Outcomes of Cervical Disc Arthroplasty versus Anterior Cervical Discectomy and Fusion for Treatment of Symptomatic Cervical Disc Di…
2015
Purpose This study aimed to investigate the mid- to long-term outcomes of cervical disc arthroplasty (CDA) versus anterior cervical discectomy and fusion (ACDF) for the treatment of 1-level or 2-level symptomatic cervical disc disease. Methods Medline, Embase, and the Cochrane Central Register of Controlled Trials databases were searched to identify relevant randomized controlled trials that reported mid- to long-term outcomes (at least 48 months) of CDA versus ACDF. All data were analyzed by Review Manager 5.3 software. The relative risk (RR) and 95% confidence intervals (CIs) were calculated for dichotomous variables. The weighted mean difference (WMD) and 95%CIs were calculated for conti…
Pharmacokinetics of new oral anticoagulants: implications for use in routine care
2018
Introduction: Since 2008, new oral anticoagulants (NOACs) have been approved for the prevention of venous thromboembolism (VTE) in patients receiving hip or knee replacement surgery, prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF), treatment of deep vein thrombosis (DVT), and pulmonary embolism (PE). Premarketing randomized clinical trials (RCTs) of NOACs demonstrated their non-inferiority in terms of efficacy vs. warfarin (traditional oral anticoagulant–TOA), with lower risk of serious adverse drug reactions, especially cerebral hemorrhages. In clinical practice, pharmacokinetic aspects of NOACs have to be carefully taken into account to …
Occurrence of Microplastics in Waste Sludge of Wastewater Treatment Plants: Comparison between Membrane Bioreactor (MBR) and Conventional Activated S…
2022
In this study, the presence of microplastics in the sludge of three wastewater treatment plants (WWTPs) was examined. The investigated WWTPs operated based on a conventional activated sludge (CAS) process, with (W1) or without (W2) primary clarification, and a membrane bioreactor process (MBR) (W3). The microplastics (MPs) concentration in the samples of W3 was approximately 81.1 ± 4.2 × 103 particles/kg dry sludge, whereas MPs concentrations in W1 and W2 were 46.0 ± 14.8 × 103 particles/kg dry sludge and 36.0 ± 5.2 × 103 particles/kg dry sludge, respectively. Moreover, MPs mainly consisted of fragments (66–68%) in the CAS plants, whereas the fra…
AN INTEGRATED APPROACH FOR THE HCl AND METALS RECOVERY FROM WASTE PICKLING SOLUTIONS: PILOT PLANT DESIGN AND OPERATIONS
2020
Pickling is one of the key steps in the hot-dip galvanizing process, where HCl solutions are largely used to remove metal oxides from metallic surfaces, thus generating spent waste liquors containing high concentrations of metals and acid. Disposal of the industrial pickling waste dramatically affects the hot-dip galvanizing industry economics and environmental footprint. Thus, reducing strong acid waste disposal is one of the most beneficial steps to enhance the process sustainability. Moreover, the continuous regeneration of pickling solutions enhances pickling rate and process performance, also minimizing industrial wastewater disposal and chemicals consumption promoting the circular use…
DEVELOPMENT AND MODELING OF MEMBRANE PROCESSES FOR THE REGENERATION OF ACID PICKLING SOLUTIONS
2021
The doctoral thesis focuses on a novel integrated process for the recovery and valorisation of acid and metal salts present in the waste solutions of the pickling process. The proposed process is based on the integration of two innovative membrane technologies, the Diffusion Dialysis and the Membrane Distillation, coupled with a reactive precipitation section. This hybrid process allows the recovery and the enhancement of waste solutions, as well as optimal operating conditions for the continuous pickling process, thus improving its efficiency. Hydrochloric acid recovery was assessed through a detailed study on the Diffusion Dialysis process by implementing a wide experimental campaign usin…
DESMILS : a decision support approach for multi-item lot sizing using interactive multiobjective optimization
2023
AbstractWe propose a decision support approach, called DESMILS, to solve multi-item lot sizing problems with a large number of items by using single-item multiobjective lot sizing models. This approach for making lot sizing decisions considers multiple conflicting objective functions and incorporates a decision maker’s preferences to find the most preferred Pareto optimal solutions. DESMILS applies clustering, and items in one cluster are treated utilizing preferences that the decision maker has provided for a representative item of the cluster. Thus, the decision maker provides preferences to solve the single-item lot sizing problem for few items only and not for every item. The lot sizes …