Search results for "Triazine"

showing 10 items of 185 documents

CCDC 904080: Experimental Crystal Structure Determination

2013

Related Article: Zulema Arcís-Castillo, M. Carmen Muñoz, Gábor Molnár, Azzedine Bousseksou, José Antonio Real|2013|Chem.-Eur.J.|19|6851|doi:10.1002/chem.201203559

Space GroupCrystallographycatena-[bis(mu3-246-tris(4-pyridyl)-135-triazine)-dodecakis(mu2-cyano)-hexa-silver-tri-iron dichloromethane solvate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 910382: Experimental Crystal Structure Determination

2013

Related Article: Y.Inokuma,S.Yoshioka,J.Ariyoshi,T.Arai,Y.Hitora,K.Takada,S.Matsunaga,K.Rissanen,M.Fujita|2013|Nature (London)|495|461|doi:10.1038/nature11990

Space GroupCrystallographycatena-[bis(mu3-246-tris(Pyridin-4-yl)-135-triazine)-hexakis(iodo)-tri-zinc(ii) 7-isopropyl-14-dimethylazulene clathrate unknown solvate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 910384: Experimental Crystal Structure Determination

2013

Related Article: Y.Inokuma,S.Yoshioka,J.Ariyoshi,T.Arai,Y.Hitora,K.Takada,S.Matsunaga,K.Rissanen,M.Fujita|2013|Nature (London)|495|461|doi:10.1038/nature11990

Space GroupCrystallographycatena-[bis(mu~3~-246-tris(Pyridin-4-yl)-135-triazine)-hexakis(iodo)-tri-zinc(ii) 4-nitrobenzaldehyde clathrate unknown solvate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 910394: Experimental Crystal Structure Determination

2013

Related Article: Y.Inokuma,S.Yoshioka,J.Ariyoshi,T.Arai,Y.Hitora,K.Takada,S.Matsunaga,K.Rissanen,M.Fujita|2013|Nature (London)|495|461|doi:10.1038/nature11990

Space GroupCrystallographycatena-[tetrakis(mu3-246-tris(4-pyridyl)triazine)-dodeca-iodo-hexa-zinc hemikis(miyakosyne A) clathrate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Hydration/elimination reactions of trapped protonated fluoroalkyl triazines

2007

Spectrometry Mass Electrospray IonizationHydrocarbons FluorinatedTriazinesChemistryIONIZATION MASS-SPECTROMETRYWaterProtonationFLUORINATED HETEROAROMATIC-COMPOUNDS5-MEMBERED RINGSElimination reactionComputational chemistry2 HETEROATOMSProtonsHETEROCYCLESSpectroscopyJournal of Mass Spectrometry
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11H‑Pyrido[3′,2′:4,5]pyrrolo[3,2‑c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2‑c][1,2,3]benzotriazine: Two New Ring Systems with Antitumor Activity

2014

Derivatives of new ring systems 11H-pyrido[3',2':4,5]pyrrolo[3,2-c]cinnoline and pyrido[3',2':4,5]pyrrolo[1,2-c][1,2,3]benzotriazine have been prepared from the key intermediates 2-(1H-pyrrolo[2,3-b]pyridin-2-yl)anilines in excellent yields (94-99%) and screened by the National Cancer Institute (Bethesda, MD) on about 60 human tumor cell lines derived from nine cancer cell types. The tested compounds exhibited antiproliferative activity against all the human cell lines, showing comparable MG_MID (mean graph midpoint) values in the range of 0.74-1.15 μM. A particular efficacy was observed against the leukemia subpanel (GI50 = 0.73-0.0090 μM). Flow cytometric analysis of the cell cycle demons…

StereochemistryCinnolines; triazinesChemistry PharmaceuticalAntineoplastic AgentsApoptosisHeterocyclic Compounds 2-RingHeterocyclic Compounds 4 or More Ringschemistry.chemical_compoundJurkat CellsCell Line TumorNeoplasmsDrug DiscoverytriazinesHumansCinnolineCell Proliferationchemistry.chemical_classificationReactive oxygen speciesCell DeathChemistryCell growthCell CycleCell MembraneTemperatureDepolarizationCell cycleCaspase InhibitorsMitochondriaEnzyme ActivationCell cultureApoptosisCaspasesCinnolines triazinesCancer cellMolecular MedicineLysosomesReactive Oxygen SpeciesCinnolines
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Synthesis and in vitro antileukemic activity of new 4-triazenopyrazole derivatives

2003

Several new 4-(3,3-dimethyltriazeno)-5-benzamidopyrazole derivatives were prepared by reacting 4-diazo-5-benzamidopyrazole derivatives with dimethylamine. The compounds were tested at 10 microM for their vitro antileukemic activity against K562 (Human chronic myelogenous leukemia) and Raji (human Burkitt limphoma ) cell lines. Dacarbazine and methotrexate were used for comparative purpose. The 3-methyl-4-(3,3-dimethyltriazeno)-5-(substituted benzamido)pyrazoles, bearing the pyrazole nucleus free at 1 position, resulted more active than the 1-(substituted phenyl)-3-methyl-4-(3,3-dimethyltriazeno)-5-benzamidopyrazoles. Dacarbazine at 10 microM showed no activity in the above tests. The observ…

StereochemistryDacarbazinePharmaceutical ScienceAntineoplastic AgentsPyrazoleSettore BIO/19 - Microbiologia GeneraleInhibitory Concentration 50Structure-Activity Relationshipchemistry.chemical_compoundCytochrome P-450 Enzyme SystemCell Line TumorLeukemia Myelogenous Chronic BCR-ABL PositiveDrug DiscoverymedicineHumansDimethylamine4-Triazenopyrazoles Antiproliferative activity In vitro antileukemic acitivityDemethylationTriazinesGeneral MedicineBurkitt LymphomaSettore CHIM/08 - Chimica FarmaceuticaIn vitroRaji cellchemistryMechanism of actionPyrazolesGrowth inhibitionmedicine.symptommedicine.drugIl Farmaco
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[Fe(TPT)(2/3){M(I)(CN)2}2]⋅nSolv (M(I) = Ag, Au): new bimetallic porous coordination polymers with spin-crossover properties.

2013

Two new heterobimetallic porous coordination polymers with the formula [Fe(TPT)2/3{MI(CN)2}2]¿nSolv (TPT=[(2,4,6-tris(4-pyridyl)-1,3,5-triazine]; MI=Ag (nSolv=0, 1¿MeOH, 2¿CH2Cl2), Au (nSolv=0, 2¿CH2Cl2)) have been synthesized and their crystal structures were determined at 120¿K and 293¿K by single-crystal X-ray analysis. These structures crystallized in the trigonal R-3m space group. The FeII ion resides at an inversion centre that defines a [FeN6] coordination core. Four dicyanometallate groups coordinate at the equatorial positions, whilst the axial positions are occupied by the TPT ligand. Each TPT ligand is centred in a ternary axis and bridges three crystallographically equivalent Fe…

StereochemistryIronCrystal structure010402 general chemistry01 natural sciencesCatalysismol structure spin crossover pyridyltriazine iron silver gold cyanideIonSpin crossoverMössbauer spectroscopyMolecule[CHIM.COOR]Chemical Sciences/Coordination chemistryBimetallic strippyridyltriazine iron silver gold cyanide prepn crystal structure010405 organic chemistryChemistryOrganic ChemistryGeneral ChemistrySelf-assemblySpin crossover0104 chemical sciencesCoordination polymersCrystallographyFISICA APLICADATernary operationPorositysilver gold bimetallic porous iron pyridyltriazine polymer spin crossoverNatural bond orbitalChemistry (Weinheim an der Bergstrasse, Germany)
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Herbizide, VI [1] kernfluorierte 2,4-dianilino-6-(dihexylamino)-1,3,5-triazine

1985

Zusammenfassung Auf dem Wege der nucleophilen Substitution der Chloratome in 2,4-Dichlor- 6-(dihexylamino)-1,3,5-triazin durch Anilin werden das 2,4-Dianilino-6-(dihexylamino)-1,3,5-triazin und durch fluorierte Amine die (Dihexylamino)- 1,3,5-triazine mit den folgenden Resten zuganglich: (2-Fluoranilino)-, (3-Fluoranilino)-, (4-Fluoranilino)-, (2,4-Difluoranilino)-, (2,5-Difluoranilino)- und (2,6-Difluoranilino)-. Zur Charakterisierung der neuen Verbindungen sind die IR-, 1 H-NMR- und Massenspektroskopie herangezogen worden. 2,4-Bis-(2,4-difluoranilino)-6-(dihexylamino)-1,3,5-triazin vermag insbesondere herbizide und antidiabetische Wirkungen auszuuben.

StereochemistryOrganic ChemistryNuclear magnetic resonance spectroscopyBiochemistryMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundAnilinechemistry135-TriazineNucleophilic substitutionMass spectrumEnvironmental ChemistryPhysical and Theoretical ChemistryJournal of Fluorine Chemistry
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On the Structure and Chiral Aggregation of Liquid Crystalline Star‐Shaped Triazines H‐Bonded to Benzoic Acids

2020

The ability of a star-shaped tris(triazolyl)triazine derivative to hierarchically build supramolecular chiral columnar organizations through the formation of H-bonded complexes with benzoic acids was studied from a theoretical and experimental point of view. The combined study has been done at three different levels including the study of the structure of the triazine core, the association with benzoic acids in stoichiometry 1:3, and the assembly of 1:3 complexes in helical aggregates. Although the star-shaped triazine core crystallizes in a non-C3 conformation, the C3 -symmetric conformation is theoretically predicted to be more stable and gives rise to a favorable C3 supramolecular 1:3 co…

Supramolecular chirality010405 organic chemistryOrganic ChemistrySupramolecular chemistryStackingMesophaseGeneral Chemistry010402 general chemistry01 natural sciencesCatalysis0104 chemical sciencesCrystallographychemistry.chemical_compoundchemistryLiquid crystalSelf-assemblyChirality (chemistry)TriazineChemistry – A European Journal
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