Search results for "Trie"
showing 10 items of 4468 documents
New insight into the inhibition of the inflammatory response to experimental delayed-type hypersensitivity reactions in mice by scropolioside A.
2006
Scropolioside A, an iridoid isolated from Scrophularia auriculata ssp. pseudoauriculata, showed anti-inflammatory properties against different experimental models of delayed-type hypersensitivity. This iridoid reduced the oedema induced by oxazolone by 79% (72 h) at 0.5 mg/ear while reducing that induced by sheep red blood cells by 47% (18 h), 45% (24 h) and 36% (48 h) at 10 mg/kg. In vivo it reduced both oedema formation and cell infiltration whereas in vitro it reduced the proliferation of activated T-lymphocytes (IC50 of 67.74 microM). Treatment with scropolioside A (100 microM) 18 and 24 h after phytohemagglutinin stimulation increased the number of cells arrested in the subG(0) phase w…
LTB4 is present in exudative pleural effusions and contributes actively to neutrophil recruitment in the inflamed pleural space
2004
SUMMARY The pleural space is a virtual compartment between the lung and chest wall that becomes filled with fluid and inflammatory cells during a variety of respiratory diseases. Here, we study the potential role of the eicosanoid metabolite leukotriene B4 (LTB4) in disparate diseases leading to acute (pneumonia) or chronic (tuberculosis, cancer) inflammation of the pleural space. LTB4 concentrations were significantly higher in pleural fluid due to pneumonia, tuberculosis and cancer with respect to congestive heart failure and correlated with neutrophil elastase, which is used as an indication of state of activation of neutrophils in the pleural space. Moreover, pleural LTB4 was biological…
Inhibition of leukocyte functions by the alkaloid isaindigotone from Isatis indigotica and some new synthetic derivatives.
2001
The alkaloid isaindigotone (1a) and seven derivatives have been synthesized to study their influence on several leukocyte functions and the generation of inflammatory mediators. Isaindigotone (1a) was found to be a scavenger of superoxide generated either by the hypoxanthine/xanthine oxidase system or stimulated human neutrophils. Isaindigotone (1a) and its acetylated derivative (1b) also inhibited 5-lipoxygenase activity and leukotriene B(4) production in these cells, whereas none of the compounds affected degranulation. In RAW 264.7 macrophages stimulated with lipopolysaccharide, synthetic derivatives exerted higher inhibitory effects on prostaglandin E(2) (PGE(2)) and nitric oxide (NO) g…
Making the most of information technology & systems usage: A literature review, framework and future research agenda
2015
Literature review on information technology & systems (IT/S) from January 2000 to December 2014.Total 152 relevant articles were found and classified into four main domains.Literature on IT/S continuous usage lacks a clear roadmap and agenda.Most research conducted in East Asia and North America.Technology acceptance model (TAM) the most used theory. This detailed literature review has considered a relatively large quantity (152 total) of scholarly empirical publications, conference proceedings, books and popular market reports published over the last 15years, i.e., from January 2000 to December 2014, in the field of human continuous usage behavior and in the context of information technolo…
La continuation des Fastes d’Ovide par les Dijonnais Claude Barthélemy Morisot : l’analyse stylométrique de deux styles encomparaison
2021
La présentation commencera par une brève contextualisation de la recherche : Claude-Barthélemy Morisot (auteur dijonnais du XVIe siècle) a complété l’œuvre des Fastes d’Ovide, en écrivant les 6 livres de conclusion. Outre l’édition critique du texte, la thèse de l’intervenante vise à analyser le style de Morisot à l’aide de la textométrie afin de quantifier dans quelle mesure un auteur de la Renaissance parvient à rapprocher son style de celui de son modèle latin. La présentation montrera rapidement les étapes préliminaires pour la préparation du corpus et se concentrera davantage sur l’analyse stylométrique.Les différentes méthodes d’analyse seront présentées en détail en expliquant leur e…
The European NAFLD Registry: A real-world longitudinal cohort study of nonalcoholic fatty liver disease
2020
© 2020 The Author(s).
Dynamics of liver stiffness by transient elastography in patients with chronic hepatitis C virus infection receiving direct-acting antiviral therapy-…
2020
The impact of direct-acting antiviral (DAA) therapies on fibrosis regression remains uncertain. In the current study, we prospectively evaluated dynamics of liver stiffness by transient elastography (TE) in patients with chronic HCV infection receiving DAA-based treatment. Patients (260) were enrolled in the German Hepatitis C-Registry (DHC-R), a national multicentre real-world cohort. Liver stiffness (LS) was assessed at baseline, end of treatment (EOT) and 24 weeks after EOT (FU24) by TE. Biochemical, virological and clinical data were obtained in parallel. In patients with SVR, there was a significant improvement of LS between baseline (median [range], 8.6 [1.7-73.5] kPa) and FU24 (7.9 […
Stratégies d'influences et politiques de maîtrise de la croissance locale
2010
Over the last ten years, real estate prices have risen considerably and accordingly to most observers, this can at least partly be attributed to an insufficient supply, due to local growth control measures. This thesis tries to understand what motivates local authorities implementing such policies. Local politicians are considered as opportunistic and their decision is modelled as the result of a political struggle between different land-related interests. This game for influence mainly opposes the owners of developed and undeveloped land, who find allies amongst local business interests that might form growth or ideas machines. Our first model describes this struggle under different hypoth…
A New Wavelet-Based Texture Descriptor for Image Retrieval
2007
This paper presents a novel texture descriptor based on the wavelet transform. First, we will consider vertical and horizontal coefficients at the same position as the components of a bivariate random vector. The magnitud and angle of these vectors are computed and its histograms are analyzed. This empirical magnitud histogram is modelled by using a gamma distribution (pdf). As a result, the feature extraction step consists of estimating the gamma parameters using the maxima likelihood estimator and computing the circular histograms of angles. The similarity measurement step is done by means of the well-known Kullback-Leibler divergence. Finally, retrieval experiments are done using the Bro…