Search results for "Trie"

Recherches sur la pluviométrie de la corne orientale de l'Afrique

1991

The Eastern Horn of Africa (Somalia, Ethiopia, Djibouti and Kenya) exhibits strong rainfall anomalies, considering the latitudinal position of the region. The mean annual rainfall map shows a vigorous meridian contrast between the rainy Western Highlands of Kenya and Ethiopia, and the deficiency of the lowlands of Somalia, the Eastern parts of Kenya and Ethiopia, and the Red Sea coast. This opposition is mainly related to the northern summer season, during which the different caracteristics of the wet "west-african" monsoon and the dry divergent "indian" monsoon are clearly emphasized. They induce single-maximum summer rainfall regimes, and double-peak spring and autumn regimes, respectivel…

The use of Endurant stent-graft for abdominal aortic aneurysm: the story about extension of instruction for use with persistent good results of stent…

2012

The Endurant stent-graft (Medtronic, Inc., Minneapolis, MN, USA) is a latest generation device for the treatment of abdominal aortic aneurysm. The idea behind designing such a graft came from the intention to broad the instruction for use (IFU) and to enable it to treat more challenging anatomy including the 10mm neck lengths, and more severe suprarenal and infrarenal angulations. Endurant stent-graft has active fixation through suprarenal stent with anchoring pins to provide migration resistance, optimized heights of stents and spacing between them for improved flexibility and conformability, low-profile delivery system with hydrophilic coating and controlled simple deployment mechanism. S…

Factors influencing inclusion in digestive cancer clinical trials: A population-based study

2015

Inclusion in a randomized therapeutic trial represents an optimal therapeutic strategy.To determine the influence of demographic characteristics and deprivation on the enrolment of patients in digestive cancer clinical trials.Between 2004 and 2010, 4632 patients were recorded by the Burgundy Digestive Cancer Registry. According to a balancing score, the 136 patients included in a clinical trial were matched with 272 patients who met the eligibility criteria for trials. Deprivation was measured by the ecological European deprivation index. A conditional multivariate logistic regression was performed.Patients aged over 75 years were significantly less likely to be included in clinical trials …

Rare Tumors in Children and Adolescents - the STEP Working Group's Evolution to a Prospective Registry.

2021

Background Very rare tumors (VRT) in children and adolescents have such a low incidence that until recently, they have not been integrated into the clinical and scientific network of pediatric oncology. Data is very limited and consistent treatment strategies are missing. Thus, VRTs are classic orphan diseases. To counteract this problem, the Arbeitsgemeinschaft für Seltene Tumorerkrankungen in der Pädiatrie (STEP) was founded. Here we report on patient recruitment during the first 10 years. Patients Patients aged up to 18 years and not included in any other clinical trial or GPOH registry were included in this analysis. Methods Data was collected from 2008 to 2018 by means of a standardize…

Fallzahlplanung bei ophthalmologischen Studien*

2000

An essential aspect in the cooperation of clinic and biometry consists in designing of studies, e.g. during the preparation of grant applications or for review by official drug surveillance institutions. A central aspect in study planning is the design-adequate and well-documented prediction of sample size, which should be recommended for any intended study. Based on several examples for sample size planning in study designs, which are of common relevance for ophthalmology, guidelines are derived to enable clinical researchers to perform sample size planning on their own. The latter can be based on the various available software packages for sample size prediction.

Distance Functions, Clustering Algorithms and Microarray Data Analysis

2010

Distance functions are a fundamental ingredient of classification and clustering procedures, and this holds true also in the particular case of microarray data. In the general data mining and classification literature, functions such as Euclidean distance or Pearson correlation have gained their status of de facto standards thanks to a considerable amount of experimental validation. For microarray data, the issue of which distance function works best has been investigated, but no final conclusion has been reached. The aim of this extended abstract is to shed further light on that issue. Indeed, we present an experimental study, involving several distances, assessing (a) their intrinsic sepa…

Propriété industrielle. Codification

1992

International audience; (Loi n° 92-597 du 1er juillet 1992)

Blocking NMDA-receptors in the pigeon's "prefrontal" caudal nidopallium impairs appetitive extinction learning in a sign-tracking paradigm

2015

Extinction learning provides the ability to flexibly adapt to new contingencies by learning to inhibit previously acquired associations in a context-dependent manner. The neural networks underlying extinction learning were mostly studied in rodents using fear extinction paradigms. To uncover invariant properties of the neural basis of extinction learning, we employ pigeons as a model system. Since the prefrontal cortex of mammals is a key structure for extinction learning, we assessed the role of N-methyl-D-aspartate receptors (NMDARs) in the nidopallium caudolaterale, the avian functional equivalent of mammalian prefrontal cortex. Since NMDARs in prefrontal cortex have been shown to be rel…

Studying Utility of Personal Usage-History: A Software Tool for Enabling Empirical Research

2007

Managing personal information space and working context is complicated in computerized environment. One well-known cause for the problem is that digital information is superficially fragmented into different data types and structures. Several unifying approaches have been proposed to facilitate semantic connections between them. Particularly in personal information retrieval, temporal information has turned to be useful. Hence, in this article, we present an empirical research setting for studying the utility of representing personal usage-history in information retrieval by comparing it with more traditional hierarchical representation. The research setting is based on a software Tool that…

2018

This article explores promising points of contact between philosophy and the expanding field of virtual reality research. Aiming at an interdisciplinary audience, it proposes a series of new research targets by presenting a range of concrete examples characterized by high theoretical relevance and heuristic fecundity. Among these examples are conscious experience itself, “Bayesian” and social VR, amnestic re-embodiment, merging human-controlled avatars and virtual agents, virtual ego-dissolution, controlling the reality/virtuality continuum, the confluence of VR and artificial intelligence (AI) as well as of VR and functional magnetic resonance imaging (fMRI), VR-based social hallucinations…