Search results for "Tritium"

showing 10 items of 165 documents

Effects of external energetic factors on tritium release from the EXOTIC 8-3/13 neutron-irradiated beryllium pebbles

2009

Abstract Tritium release from samples of 9–13 mg of the EXOTIC 8-3/13 neutron-irradiated beryllium pebbles under the separate and simultaneous action of temperature 490–770 K, 5 MeV fast-electron radiation 14 MGy h−1 for 3 h and magnetic field (MF) of 1.7 T was investigated. The pebbles were found to be very dissimilar with respect to their total tritium content—2.5–9 MBq g−1. The batch contained also some coarse agglomerates of the pebbles containing 10–19 MBq g−1 of tritium having also a high tritium release. For the pebbles having the total tritium 2.5–5.3 MBq g−1, the electron radiation for 3 h caused the fractional tritium release 17–26% (B = 0) and 21–29% (B = 1.7 T), the temperature …

Materials scienceMechanical EngineeringRadiochemistrychemistry.chemical_elementBlanketFusion powerNuclear physicsNuclear Energy and EngineeringchemistryAgglomerateGeneral Materials ScienceNeutronTritiumIrradiationBerylliumHeliumCivil and Structural EngineeringFusion Engineering and Design
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Behaviour of advanced tritium breeder pebbles under simultaneous action of accelerated electrons and high temperature

2017

The authors greatly acknowledge the technical and experimen-tal support of O. Valtenbergs and L. Avotina (Institute of Chemical Physics, University of Latvia). The work is performed in the frames of the University of Latvia financed project No. Y9-B044-ZF-N-300, “Nano, Quantum Technologies, and Innovative Materials for Eco-nomics”.

Materials scienceScanning electron microscopeAnalytical chemistrychemistry.chemical_element01 natural sciences7. Clean energy010305 fluids & plasmaslaw.inventionchemistry.chemical_compoundBreeder (animal)law0103 physical sciencesRadiolysis:NATURAL SCIENCES:Physics [Research Subject Categories]Tritium breeding ceramicGeneral Materials ScienceIrradiationElectron paramagnetic resonanceCivil and Structural Engineering010302 applied physicsMechanical EngineeringLithium orthosilicateMicrostructureNuclear Energy and EngineeringchemistryTritiumLithiumOrthosilicateLithium metatitanateFusion Engineering and Design
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Tritium distribution and chemical forms in the irradiated beryllium pebbles before and after thermoannealing

2011

Abstract Beryllium pebbles are foreseen as a neutron multiplier in the tritium breeding blanket of the future fusion devices. Tritium inventory in the beryllium as a result of neutron-induced transmutations is a significant safety and technological issue for the operation of the breeding blanket. In this study, beryllium pebbles from 3 different irradiation experiments: BERYLLIUM, EXOTIC 8/3-13 and PBA, performed at High Flux Reactor HFR have been investigated. The distribution of tritium in the bulk of the pebbles and the abundance ratios of chemical forms of tritium T 0 , T + and T 2 have been analysed before and after the different thermo-annealing experiments. In order to determine the …

Materials scienceScanning electron microscopeMechanical EngineeringRadiochemistrychemistry.chemical_elementThermal treatmentBlanketNuclear physicsNuclear Energy and EngineeringchemistryGeneral Materials ScienceNeutronTritiumIrradiationBerylliumPebbleCivil and Structural EngineeringFusion Engineering and Design
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Activity monitoring of a gaseous tritium source by beta induced X-ray spectrometry

2013

Abstract For monitoring and control of gaseous tritium sources in fuel circulation systems of fusion reactors beta induced X-ray spectrometry (BIXS) seems to be an applicable method. The characteristics of a BIXS monitoring setup built at TLK were examined. A low-noise silicon drift detector (SDD) was used together with two thin beryllium windows evaporated with gold films of 100 nm for efficient X-ray production. The measured X-ray intensity was proportional to the tritium partial pressure and the average detection efficiency was evaluated as 32.6 × 10−8 cps/Bq. A tritium memory effect was revealed. From the results it was concluded that such a monitoring system would be a useful complemen…

Materials scienceSilicon drift detectorSiliconMechanical EngineeringRadiochemistrychemistry.chemical_elementPartial pressureFusion powerMass spectrometryNuclear Energy and EngineeringchemistryBeta (plasma physics)General Materials ScienceTritiumBerylliumCivil and Structural EngineeringFusion Engineering and Design
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Conceptual design of the enhanced coolant purification systems for the European HCLL and HCPB test blanket modules

2019

Abstract The Coolant Purification Systems (CPSs) is one of the most relevant ancillary systems of European Helium Cooled Lead Lithium (HCLL) and Helium Cooled Pebble Bed (HCPB) Test Blanket Modules (TBMs) which are currently in the preliminary design phase in view of their installation and operation in ITER. The CPS implements mainly two functions: the extraction and concentration of the tritium permeated from the TBM modules into the primary cooling circuit and the chemistry control of helium primary coolant. During the HCLL and HCPB-TBSs (Test Blanket Systems) Conceptual Design Review (CDR) in 2015 it was recognized the need of reducing the tritium permeation into the Port Cell #16 of ITE…

Mechanical EngineeringNuclear engineeringCoolant purification systemBlanketTritium01 natural sciencesSizing010305 fluids & plasmasCoolantDesign phaseTBMNuclear Energy and EngineeringConceptual designITERCoolant purification system; ITER; TBM; Tritium0103 physical sciencesGeneral Materials Science010306 general physicsSettore ING-IND/19 - Impianti NucleariCivil and Structural EngineeringFusion Engineering and Design
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Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine

2009

Kainate receptor antagonists have potential as therapeutic agents in a number of neuropathologies. Synthetic modification of the convulsant marine toxin neodysiherbaine A (NDH) previously yielded molecules with a diverse set of pharmacological actions on kainate receptors. Here we characterize three new synthetic analogs of NDH that contain substituents at the C10 position in the pyran ring of the marine toxin. The analogs exhibited high-affinity binding to the GluK1 (GluR5) subunit and lower affinity binding to GluK2 (GluR6) and GluK3 (GluR7) subunits in radioligand displacement assays with recombinant kainate and AMPA receptors. As well, the natural toxin NDH exhibited approximately 100-f…

Models MolecularAgonistKainic acidPatch-Clamp TechniquesTime FactorsStereochemistrymedicine.drug_classProtein subunitGreen Fluorescent ProteinsGlutamic AcidKainate receptorAMPA receptorMolecular Dynamics SimulationLigandsTransfectionTritiumBinding CompetitiveArticleMembrane PotentialsRadioligand AssayStructure-Activity RelationshipCellular and Molecular Neurosciencechemistry.chemical_compoundReceptors Kainic AcidExcitatory Amino Acid AgonistsmedicineRadioligandHumansReceptoralpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidCell Line TransformedPharmacologyAlanineKainic AcidDose-Response Relationship DrugMolecular StructureChemistryBridged Bicyclo Compounds HeterocyclicProtein SubunitsBiochemistryMutagenesis Site-DirectedMarine toxinNeuropharmacology
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Unraveling the role of protein dynamics in dihydrofolate reductase catalysis

2013

Protein dynamics have controversially been proposed to be at the heart of enzyme catalysis, but identification and analysis of dynamical effects in enzyme-catalyzed reactions have proved very challenging. Here, we tackle this question by comparing an enzyme with its heavy ((15)N, (13)C, (2)H substituted) counterpart, providing a subtle probe of dynamics. The crucial hydride transfer step of the reaction (the chemical step) occurs more slowly in the heavy enzyme. A combination of experimental results, quantum mechanics/molecular mechanics simulations, and theoretical analyses identify the origins of the observed differences in reactivity. The generally slightly slower reaction in the heavy e…

Models MolecularComputational chemistryStereochemistryKineticsBiophysicsMolecular Dynamics SimulationTritiumCatalysisEnzyme catalysisReaction coordinateReaction rateMolecular dynamicsQuantum biologyEscherichia coliReactivity (chemistry)Carbon IsotopesQuantum biologyMultidisciplinaryNitrogen IsotopesChemistryProtein dynamicsBiological chemistryProteinsTetrahydrofolate DehydrogenaseKineticsChemical physicsPhysical Sciences
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Mapping of a binding site for ATP within the extracellular region of the Torpedo nicotinic acetylcholine receptor beta-subunit.

1997

Using 2,8,5'-[H-3]ATP as a direct photoaffinity label for membrane-bound nicotinic acetylcholine receptor (nAChR) from Torpedo marmorata, we have identified a binding site for ATP in the extracellular region of the beta-subunit of the receptor. Photolabeling was completely inhibited in the presence of saturating concentrations of nonradioactive ATP, whereas neither the purinoreceptor antagonists suramin, theophyllin, and caffeine nor the nAChR antagonists alpha-bungarotoxin and d-tubocurarine affected the labeling reaction. Competitive and noncompetitive nicotinic agonists and Ca2+ increased the yield of the photoreaction by up to 50%, suggesting that the respective binding sites are allost…

Molecular Sequence DataPhotoaffinity LabelsReceptors NicotinicTorpedoTritiumBiochemistryPeptide Mappingchemistry.chemical_compoundGanglion type nicotinic receptorAdenosine TriphosphateAdenine nucleotideAnimalsChymotrypsinTrypsinAmino Acid SequenceBinding siteBinding SitesbiologyHydrolysisCell MembranePeptide FragmentsNicotinic acetylcholine receptorNicotinic agonistBiochemistrychemistrybiology.proteinAlpha-4 beta-2 nicotinic receptorExtracellular SpaceAdenosine triphosphateSequence AnalysisATP synthase alpha/beta subunitsBiochemistry
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Natural micro-scale heterogeneity induced solute and nanoparticle retardation in fractured crystalline rock.

2011

Abstract We studied tracer (Tritiated Water (HTO); Tritium replaces one of the stable hydrogen atoms in the H 2 O molecule) and nanoparticle (quantum dots (QD)) transport by means of column migration experiments and comparison to 3D CFD modeling. Concerning the modeling approach, a natural single fracture was scanned using micro computed tomography (μCT) serving as direct input for the model generation. The 3D simulation does not incorporate any chemical processes besides the molecular diffusion coefficient solely reflecting the impact of fracture heterogeneity on mass (solute and nanoparticles) transport. Complex fluid velocity distributions (flow channeling and flowpath heterogeneity) evo…

Molecular diffusionGeological PhenomenaChemistryMineralogyWaterModels TheoreticalTritiumColloidFlow velocityQuantum dotChemical physicsQuantum DotsFracture (geology)Water MovementsEnvironmental ChemistryComputer SimulationDiffusion (business)PorosityGroundwaterWater Science and TechnologyComplex fluidJournal of contaminant hydrology
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Investigation of hydrogen and deuterium impact on the release of tritium from two-phase lithium ceramics under reactor irradiation

2022

In the development of fusion energy, an important task is the study and improvement of tritium production technologies. In this case, one of the most promising materials for tritium generation is lithium ceramics. Considering the importance of the task, numerous studies are aimed at solving the problem of determining the parameters and mechanisms of tritium release in lithium-containing materials. This paper presents the results of a study of tritium release processes from two-phase lithium ceramics of Li$_{4}$SiO$_{4}$/Li$_{2}$TiO$_{3}$ during reactor irradiation when hydrogen and deuterium are injected into the chamber with irradiated samples. The mechanisms regularities of the tritium yi…

Neutron irradiationTechnologyTritium releaseNuclear and High Energy PhysicsNuclear Energy and EngineeringMaterials Science (miscellaneous)TK9001-9401Nuclear engineering. Atomic powerTritiumDeuteriumddc:600Two-phase lithium ceramicNuclear Materials and Energy
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