Search results for "Tropanes"

showing 3 items of 23 documents

Effects of aclidinium on determinants of COPD severity: symptoms and quality of life

2016

Marco Contoli,1 Paolo Solidoro,2 Fabiano Di Marco,3,4 Nicola Scichilone,5 Angelo Corsico,6 Fulvio Braido,7 Pierachille Santus4,8 1Research Centre on Asthma and COPD, Department of Medical Sciences, University of Ferrara, Ferrara, Italy; 2Cardiovascular and Thoracic Department, Città della Salute, Turin, Italy; 3Department of Health Sciences, University of Milan, Milan, Italy; 4Respiratory Unit, San Paolo Hospital, Milan, Italy; 5Department of Internal Medicine, Section of Pulmonology (DIBIMIS), University of Palermo, Palermo, Italy; 6Department of Molecular Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; 7Allergy and Respiratory Diseases Clinic, DIMI, University of G…

Time FactorsReviewdaily symptomsAclidinium; COPD; Daily symptoms; LAMA; Quality of life; Pulmonary and Respiratory Medicine; Health Policy; Public Health Environmental and Occupational HealthSeverity of Illness IndexPulmonary Disease Chronic Obstructive0302 clinical medicineBronchodilatorMedicine030212 general & internal medicineLungCOPDHealth PolicyTropaneLAMAGeneral MedicineBronchodilator AgentsMuscarinic AntagonistTreatment OutcomeTolerabilityChronic inflammatory responsePublic HealthHumanPulmonary and Respiratory MedicineChronic Obstructivemedicine.medical_specialtyTime Factormedicine.drug_classBronchoconstrictionSocio-culturaleMuscarinic AntagonistsSettore MED/10 - Malattie Dell'Apparato RespiratorioPulmonary Disease03 medical and health sciencesAclidinium bromideaclidiniumAclidinium; COPD; Daily symptoms; LAMA; Quality of life; Bronchoconstriction; Bronchodilator Agents; Humans; Lung; Muscarinic Antagonists; Pulmonary Disease Chronic Obstructive; Recovery of Function; Severity of Illness Index; Time Factors; Treatment Outcome; Tropanes; Quality of LifeInternal medicineSeverity of illnessAnticholinergicCOPDHumansAdverse effectBronchodilator Agentlcsh:RC705-779business.industryEnvironmental and Occupational HealthDaily symptomPublic Health Environmental and Occupational Healthlcsh:Diseases of the respiratory systemRecovery of Functionmedicine.diseasequality of life030228 respiratory systemPhysical therapybusinessTropanesInternational Journal of Chronic Obstructive Pulmonary Disease
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Temperature effects explain continental scale distribution of cyanobacterial toxins

2018

Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other classes, such as neurotoxins (e.g., anatoxin-a) and cytotoxins (e.g., cylindrospermopsin) due to their potency. Most studies examine the relationship between individual toxin variants and environmental factors, such as nutrients, temperature and light. In summer 2015, we collected samples across Europe to investigate the effect of nutrient and temperature gradients on the variability of toxin production at a continental scale. Direct and indirect…

light climate0106 biological sciencesthermoclineBacterial toxinstoksiinitlimit of quantitationToxines bacterianesMicrocystin-LRToxicology01 natural sciencesAnatoxin-aanalogs and derivativesBLOOMSDirect EffectsuracilWater Pollutantschemistry.chemical_classificationTemperaturesFRESH-WATERlatitudemaximum buoyancy frequency6. Clean waterclimate changeIndirect effectsEUTROPHICATIONmicrocystin RRarticlesGROWTHlämpötilaLAKESmicrocystin; anatoxin; cylindrospermopsin; temperature; direct effects; indirect effects; spatial distribution; European Multi Lake Surveyepilimnetic temperatureta1172cyanobacteria lakes climate warming microcystin; anatoxin; cylindrospermopsin; temperature; direct effects; indirect effects; spatial distribution; European Multi Lake SurveyZoologyArticlewater pollutantMICROCYSTIS-AERUGINOSAAlkaloidsSettore BIO/07 - ECOLOGIANATURAL SCIENCES. Biology.Spatial distributionMicrocystis aeruginosaUracillakesyanobakteeritIndirect Effectsliquid chromatography-mass spectrometry1172 Environmental sciencesEkologinutrient010604 marine biology & hydrobiologylcsh:RmicrobiologyClimatic changesmicrocystin LRAnatoxinLakesSpatial Distributionchemistrynodularinmicrobial diversityphytoplanktonta1181CylindrospermopsinTropanesCyanobacteriaAquatic Ecology and Water Quality ManagementanalysisHealth Toxicology and Mutagenesislcsh:Medicineenvironmental parameters010501 environmental sciencesmedicine.disease_causenitrogenchemistry.chemical_compoundsea surface temperatureenvironmental factorddc:550Canvi climàticphosphorusPRIRODNE ZNANOSTI. Biologija.limit of detectionEcologyCyanobacteria ToxinsbiologyTemperaturelevinneisyysmicrocystin ; anatoxin ; cylindrospermopsin ; temperature ; direct effects ; indirect effects ; spatial distribution ; European Multi Lake SurveyNodularintropane derivativeEuropeDAPHNIA-MAGNAİndirect EffectsCylindrospermopsinDirect effectsmicrobial communityEnvironmental Monitoringhigh performance liquid chromatographyMicrocystinsClimate ChangeBacterial ToxinsMicrocystinMicrocystinCyanobacteriavälittömät oikeusvaikutuksetcyanobacteriumddc:570geographic distributionmedicinebacterial toxincontrolled studyddc:610Institut für Biochemie und Biologie0105 earth and related environmental sciencesnonhumanWIMEKToxinlongitudePHYTOPLANKTON ASSEMBLAGESEuropean Multi Lake SurveyAquatic EcologyNITROGEN AVAILABILITYanatoxin aAquatische Ecologie en Waterkwaliteitsbeheerbiology.organism_classificationClimatic changeCLIMATE13. Climate actionresponse variableCanvis climàtics
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New strategies for medical management of overactive bladder in children.

2011

Purpose of review The medical treatment of children with non-neurogenic overactive bladder syndrome (OAB) is still limited to a small number of drugs approved for use in childhood according to the national regulations of each country. Recent findings Over the last few years, there were several studies on the use of antimuscarinics other than oxybutynin in children, as well as some on the use of extended release oxybutynin and tolterodine and transdermal oxybutynin. It was shown that the combination of two different anticholinergics might be a well tolerated and successful option in children with OAB refractory to monotherapy, as well as administration of a receptor-selective antimuscarinic …

medicine.medical_specialtyQuinuclidinesBotulinum ToxinsCombination therapyTolterodine TartrateNortropanesUrologyPhenylpropanolamineUrologyUrinationMuscarinic AntagonistsBenzilatesCresolsTetrahydroisoquinolinesmedicineHumansBenzhydryl CompoundsOxybutyninIntensive care medicineChildSolifenacinbusiness.industryUrinary Bladder OveractiveStandard treatmentSolifenacin Succinatemedicine.diseaseBotulinum toxinReceptors MuscarinicOveractive bladderMandelic AcidsPropiverineTolterodinebusinessmedicine.drugCurrent opinion in urology
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