Search results for "Tubular"

Sorting signals in the cytosolic tail of plant p24 proteins involved in the interaction with the COPII coat.

2004

The ability of the cytosolic tail of a plant p24 protein to bind COPI and COPII subunits from plant and animal sources in vitro has been examined. We have found that a dihydrophobic motif in the -7,-8 position (relative to the cytosolic carboxy-terminus), which strongly cooperates with a dilysine motif in the -3,-4 position for COPI binding, is required for COPII binding. In addition, we show that COPI and COPII coat proteins from plant cytosol compete for binding to the sorting motifs in these tails. Only in the absence of the dilysine motif in the -3,-4 position or after COPI depletion could we observe COPII binding to the p24 tail. This competition is not observed when using rat liver cy…

Congenital reduction in number of nephrons accelerates renal damage, and limits proximal tubular growth response to release of neonatal partial urete…

2012

Aim: to analyze the evolution of the response to persistent partial ureteral obstruction (PUO) and obstruction/release (PUO/Rel) in mice with 50% reduction in the number of nephrons from 21 days of age (time of weaning) to 42 days of age (adulthood). Methods: C57/BL6 wild-type (WT) and mice with oligosyndactylism and 50% reduction of nephron number (Os/+), were subjected to sham operation or PUO in the first 2 days of life. Additional mice underwent release of obstruction at 7 days (PUO-Rel). The study was performed in kidneys harvested at 21 and 42 days. Using histomorphometry, glomerular area (GA) was determined by PAS staining, and fractional proximal tubular (PT) mass and intact glomeru…

Studio teorico dell’interazione host-guest fra un sistema tubolare ciclopeptidico e la cesio azide

2006

Acute renal failure and liver dysfunction after subcutaneous injection of 3-sn-phosphatidylcholine (Lipostabil®)-case report.

2011

INTRODUCTION Drug-induced tubulointerstitial nephritis and acute tubular necrosis are common, and are often caused by drugs especially antibiotics or non-steroidal anti-inflammatory drugs. Drug-induced liver dysfunction and renal failure after subcutaneous injection of phosphatidylcholine was not reported so far. 3-sn-Phosphatidylcholine has been described as a cell lysis reaction-inducing drug. Its in vitro data indicated a relevant toxicity potential. In particular human cell types such as fibroblast-like preadipocytes, vascular and skeletal muscle cells, or renal epithelial cells react more sensitive than other human cell types. CASE REPORT We present a 28-year-old woman who received 3.5…

A comparison among different kinds of stator lamination in tubular linear machines

2016

In this paper the authors perform a comparison among three different stator structures for a Tubular Permanent Magnet Linear Machine. Each structure is characterized by its own lamination which is expected to contribute to the overall performance of the machine. A detailed analysis of the main figures of merit of the three configurations has been carried out in order to identify the configuration with the best characteristics. Significant data such as flux distribution, rated voltage and current, force on the moved and power losses have been compared. The results show that the choice of a mixed stator lamination allows to improve the performance of these machines.

The effect of manufacturing tolerances on a tubular linear ferrite motor

2015

This study presents a numerical and experimental study on the effect of permanent magnet tolerances on the performances of a Tubular Linear Ferrite Motor. The statistical distribution of the magnetic characteristic of a set of commercial magnets is obtained experimentally while the performances of a the tubular motor are numerically evaluated. The performances that have been considered are: cogging force, end effect force and generated thrust. It has been shown that: 1)the statistical variability of the magnets modifies the time behavior of the cogging force; 2)the value of both the end effect cogging force and the generated thrust are directly linked to the values of then remanence field o…

PLLA/Fibrin Tubular Scaffold: A New Way for Reliable Endothelial Cell Seeding

2014

In the present work a simple and quick technique for cell seeding into tubular-shaped scaffolds, which allows a homogeneous cell distribution, was tested. The poly-L-lactide (PLLA) scaffolds, prepared via diffusion induced phase separation (DIPS), were filled with fibrin gel in order to obtain a hybrid scaffold for Vascular Tissue Engineering applications. The formation of immobilized fibrin networks on the inner surface of the tubular scaffolds was observed using confocal microscopy and SEM. Morphological analysis of the so-obtained scaffold revealed that the fibrin gel is uniformly distributed on the internal surface of the scaffold, leading to an organized structure. Moreover a penetrati…

Progettazione, realizzazione e caratterizzazione di un Generatore Lineare Tubolare a Magneti Permanenti per lo sfruttamento del moto ondoso marino

Design criteria of tubular linear induction motors and generators: A prototype realization and its characterization

2013

In this paper a mathematical model of tubular linear induction machines (TLIM) with hollowed induced part is recalled. Moreover the design criteria of a TLIM with hollowed iron induced part are presented as well as the technological processes to be adopted and the choice of materials to construct the various parts. The methodologies for mechanical assembling and electric wiring are considered too. A prototype with bimetallic induced part has been designed and built. Finally some experimental results on electrical and mechanical variables, when the machines are used as motors, are shown.

Functional annulus remodelling using a prosthetic ring in tricuspid aortic valve repair: mid-term results

2013

OBJECTIVES: The functional aortic valve annulus (FAVA) is a complex unit with proximal (aorto-ventricular junction) and distal (sinotubular junction) components. The aim of our study was to evaluate the impact of the total FAVA remodelling, using a prosthetic ring, on mid-term clinical and echocardiographic-RESULTS:-after aortic valve repair. METHODS: Since February 2003, 250 patients with tricuspid aortic valve insufficiency (AI) underwent aortic valve repair. FAVA dilatation was treated by prosthetic ring in 52 patients, by isolated subcommissural plasty in 62, by subcommissural plasty plus ascending aortic replacement in 57 and by David's reimplantation procedure in 79. Survival rate and…