Search results for "Tv"

showing 10 items of 4565 documents

Association of microsatellite polymorphisms of the human 14q13.2 region with type 2 diabetes mellitus in Latvian and Finnish populations.

2007

A polymorphic microsatellite in intron 6 of the human proteasome core particle PSMA6 gene (HSMS006), and four other microsatellites localized upstream on human chromosome 14q13.2 (HSMS801, HSMS702, HSMS701, HSMS602), were genotyped in 104 type 2 diabetic patients and 129 age-matched control subjects from Latvia and replicated in 91 type 2 diabetic patients and 88 age-matched healthy control subjects from the Botnia Study in Finland. In type 2 diabetic patients from both populations the HSMS006 (TG)22 allele was two times more frequent compared to the control group. In the Latvian population the (CAA)8 allele of the HSMS602 marker was less frequent in the diabetic group, as was the (AC)24 al…

AdultMaleProteasome Endopeptidase ComplexPopulationPSMA6Type 2 diabetesBiologyGene FrequencyPolymorphism (computer science)Multienzyme ComplexesGeneticsmedicineHumansAlleleeducationAllele frequencyGenetics (clinical)AllelesFinlandAgedGeneticsChromosomes Human Pair 14education.field_of_studyPolymorphism GeneticType 2 Diabetes MellitusMiddle Agedmedicine.diseaseLatviaDiabetes Mellitus Type 2Case-Control StudiesMicrosatelliteFemaleMicrosatellite RepeatsAnnals of human genetics
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Retrospective dosimetry for Latvian workers at Chernobyl.

2001

Between 1986 and 1991 approximately 6500 Latvian inhabitants were recruited for clean-up work at the Chernobyl nuclear power plant. Their absorbed doses are usually unknown, because less than half of them had their external exposure officially documented. Clinical investigations show a high morbidity rate for these clean-up workers when compared with that of the general population. In order to understand the causes of their diseases and the impact of ionising radiation, electron spin resonance (ESR) has been used to measure the absorbed doses in human tooth enamel. The doses estimated by ESR were between two and three times higher than previously documented and are in accord with the result…

AdultMaleRadiobiologyPopulationRadiation DosageRisk AssessmentSeverity of Illness IndexIonizing radiationRadiation MonitoringEnvironmental healthOccupational ExposureDosimetryMedicineHumansRadiology Nuclear Medicine and imagingeducationRadiation InjuriesRetrospective StudiesRadionuclideeducation.field_of_studyRadiationRadiological and Ultrasound Technologybusiness.industryMortality rateIncidenceRadiation dosePublic Health Environmental and Occupational HealthElectron Spin Resonance SpectroscopyGeneral MedicineMiddle AgedLatviaSurvival AnalysisOccupational exposureNuclear medicinebusinessRadioactive Hazard ReleaseUkraineToothRadiation protection dosimetry
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Psychological variables underlying political orientations in an old and a new democracy: A comparative study between Sweden and Latvia.

2016

This study examines in detail the psychological variables underlying ideological political orientation, and structure and contents of this orientation, in Sweden and Latvia. Individual political orientation is conceptualized on two dimensions: acceptance vs. rejection of social change and acceptance vs. rejection of inequality. Swedish (N = 320) and Latvian (N = 264) participants completed measures of political orientation, Social Dominance Orientation (SDO), Right Wing Authoritarianism (RWA), self vs. other orientation, tolerance for ambiguity, humanism and normativism, core political values, system justification, as well as moral foundations questionnaire and portrait values questionnaire…

AdultMaleSocial ValuesPoison control050109 social psychologySocial TheorySocial value orientationsModels PsychologicalMoralsAuthoritarianism050105 experimental psychologyBiology and political orientationYoung AdultArts and Humanities (miscellaneous)Developmental and Educational PsychologyHumans0501 psychology and cognitive sciencesGeneral PsychologySweden05 social sciencesAuthoritarianismSocial changePoliticsRight-wing authoritarianismGeneral MedicineDemocracyLatviaAttitudeSocial DominanceSocioeconomic FactorsFemaleSystem justificationPsychologySocial dominance orientationSocial psychologyScandinavian journal of psychology
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Point mutations associated with Leber hereditary optic neuropathy in a Latvian population

2013

Purpose To study mutations associated with Leber hereditary optic neuropathy (LHON) in patients suspected of having this mitochondrial disorder in a Latvian population. Additional aims were to determine the heteroplasmy status of all non-synonymous polymorphisms identified in the current study and to identify the mitochondrial haplogroups of the studied participants because these factors may contribute to the manifestation of LHON. Methods Twelve patients, including patients in two families, were enrolled in the current study. LHON was suspected based on the findings of ophthalmologic examinations. In clinically affected individuals, the presence of all previously reported LHON-associated m…

AdultMalecongenital hereditary and neonatal diseases and abnormalitiesPolymorphism Geneticgenetic structuresnutritional and metabolic diseasesOptic Atrophy Hereditary LeberSequence Analysis DNAMiddle AgedDNA MitochondrialLatviaeye diseasesWhite PeopleMitochondriaPedigreeHaplotypesHumansPoint MutationFemaleResearch Article
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The 12-month prevalence of depression and health care utilization in the general population of Latvia.

2017

Abstract Background This cross-sectional study aims to assess the 12-month prevalence of major and minor depression in the Latvian population, and to evaluate associated health care utilization. Methods Trained interviewers conducted face-to-face interviews with a multistage stratified probability sample of the Latvian general population, ages 15–64 (n=3003). Participants were interviewed using the depression module of the Mini International Neuropsychiatric Interview. Self-reported health care utilization and somatic illness were also assessed. Multinomial logistic regressions were applied. Results The 12-month prevalence of major depression was 7.9% (95%CI 7.0–8.9), while for minor depres…

AdultMalemedicine.medical_specialtyAdolescentHealth StatusPopulationLogistic regressionSampling Studies03 medical and health sciencesYoung Adult0302 clinical medicineSex FactorsHealth careEpidemiologyOdds RatioPrevalenceMedicineHumansDisabled Persons030212 general & internal medicineeducationPsychiatryDepression (differential diagnoses)Mini-international neuropsychiatric intervieweducation.field_of_studyDepressive Disorderbusiness.industryDepressionAge FactorsHealth ServicesMiddle AgedPatient Acceptance of Health CareDisability pensionLatvia030227 psychiatryPsychiatry and Mental healthClinical PsychologyCross-Sectional StudiesLogistic ModelsRelative riskFemaleSelf ReportbusinessDemographyJournal of affective disorders
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Prevalence of blood-borne viral infections (cytomegalovirus, human herpesvirus-6, human herpesvirus-7, human herpesvirus-8, human T-cell lymphotropic…

2002

The identification of blood-borne viral infections is important in transfusion medicine. The aim of this study was to evaluate the prevalence of human herpesvirus (HHV) [cytomegalovirus (CMV), HHV-6, HHV-7 HHV-8] and human retrovirus (HRV) (human T-cell lymphotropic virus (HTLV)-I/II, HRV-5) infections among apparently healthy Latvian blood donors. DNA extracted from peripheral blood leukocytes (PBL) of 150 individuals was tested for herpesviruses by sensitive polymerase chain reaction (PCR) technique. None of the blood donors was positive for HHV-8 infection, while the incidence of latent beta-herpesvirus infections was high: single infection by CMV, HHV-6, and HHV-7 was detected in 2.6%, …

AdultMalemedicine.medical_specialtyAdolescentHerpesvirus 6 HumanvirusesRoseolovirus InfectionsBlood DonorsHerpesvirus 7 HumanBiologymedicine.disease_causeHerpesviridaeVirusInternal medicinemedicineHumansAgedHematologyvirus diseasesReceptors Interleukin-2CytomegalovirusHerpesviridae InfectionsHematologyGeneral MedicineMiddle AgedProvirusbiology.organism_classificationHTLV-I InfectionsLatviaVirologyBloodCytomegalovirus InfectionsDNA ViralHTLV-II InfectionsHerpesvirus 8 HumanImmunologyHTLV-II InfectionsFemaleHuman herpesvirus 6Viral diseaseBiomarkersRetroviridae InfectionsAnnals of Hematology
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Adaptation and validation of the Patient Health Questionnaire-9 to evaluate major depression in a primary care sample in Latvia

2017

Background: Depression is one of the most common mental disorders in primary care settings and is often underdiagnosed and undertreated by general practitioners (GPs). To date, no depression screening instruments have been validated for use in primary care settings in Latvia. The aim of this study was to establish the validity and cutoff score of the Patient Health Questionnaire-9 (PHQ-9) among primary care patients in Latvia. Materials and methods: During a one-week period, all consecutive patients aged 18 years or older visiting their GP of health concerns at 6 primary care settings were invited to complete the PHQ-9 questionnaire in their native language (Latvian or Russian). Criterion v…

AdultMalemedicine.medical_specialtyAdolescentPrimary health careSample (statistics)Primary carePatient Health QuestionnaireSensitivity and SpecificityYoung Adult03 medical and health sciences0302 clinical medicinemedicineHumansMass ScreeningTranslations030212 general & internal medicineYoung adultPsychiatryMass screeningDepression (differential diagnoses)AgedAged 80 and overDepressive Disorder MajorPrimary Health Carebusiness.industryReproducibility of ResultsMiddle AgedLatviaPatient Health QuestionnairePsychiatry and Mental healthFemaleDepression screenbusiness030217 neurology & neurosurgery
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Confidentiality and disclosure of HIV infection: HIV-positive persons' experience with HIV testing and coping with HIV infection in Latvia.

2000

The objective of the study was to explore retrospectively HIV-infected individuals experience with HIV testing counseling and the issue of confidentiality in the Latvian context. A qualitative study using grounded theory approach and based on semi-structured in-depth interviews was implemented. 13 HIV-positive individuals above 18 were selected using purposeful sampling from the 63 HIV-positive individuals registered in Latvia between 1987 and 1997. HIV-infected people are worried that doctors sometimes disrespect confidentiality. Confidentiality was found to be a basic prerequisite for building trusting relationships between an HIV-infected individual and a doctor within the counseling pro…

AdultMalemedicine.medical_specialtyCoping (psychology)Health (social science)Self DisclosureSocial PsychologyAdolescentSocial ValuesAttitude of Health PersonnelCultureDeveloping countryHIV InfectionsSocial value orientationsGrounded theoryPoliticsNursingAdaptation PsychologicalmedicineHumansConfidentialityAgedRetrospective StudiesPhysician-Patient Relationsbusiness.industryPublic healthPublic Health Environmental and Occupational HealthAIDS SerodiagnosisMiddle AgedLatviaFemaleContact TracingbusinessConfidentialityQualitative researchAIDS care
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A Population-Based Cross-Sectional Study of Cardiovascular Risk Factor in Latvia

2012

Background and Objective. To date, the epidemiological studies of noncommunicable diseases in Latvia were more episodic and covered only selected areas. The first national crosssectional population-based survey of cardiovascular risk factors after regaining independence was carried out to provide reliable information on the cardiovascular risk factor profile in adults. Material and Methods. Computerized random sampling from the Registry of Latvian population was carried out. A total of 6000 enrolled subjects aged 25–74 years were divided into 10 age subgroups. The data of 3807 respondents (63.5% of all) were included into the final analysis. Results. The mean number of cardiovascular risk f…

AdultMalemedicine.medical_specialtyCross-sectional studyPopulationPopulationCardiovascular risk factorscardiovascular risk factors; population-based cross-sectional studyPopulation basedOverweightYoung AdultRisk FactorsEpidemiologymedicineHumansRisk factoreducationAgededucation.field_of_studybusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseLatviaObesityCross-Sectional StudiesCardiovascular DiseasesFemalemedicine.symptombusinessDemographyMedicina; Volume 48; Issue 6; Pages: 46
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Clinicopathological characteristics of Epstein-Barr virus-positive gastric cancer in Latvia

2019

Objective Epstein-Barr virus (EBV)-associated gastric cancer has been proposed to be a distinct gastric cancer molecular subtype. The prognostic significance of EBV infection in gastric cancer remains unclear and needs further investigation. Our study aimed to analyze EBV-positive and EBV-negative gastric cancer patients regarding their personal and tumor-related characteristics, and compare their overall survival. Methods Gastric cancer patients consecutively treated at the Riga East University Hospital during 2009-2016 were identified retrospectively. Tumor EBV status was determined by in-situ hybridization for EBV-encoded RNA (EBER). Information about clinicopathological characteristics …

AdultMalemedicine.medical_specialtyEpstein-Barr Virus InfectionsComorbidityKaplan-Meier EstimateAdenocarcinomaGastroenterologyHospital recordsArticle03 medical and health sciencesYoung Adult0302 clinical medicineAge DistributionStomach NeoplasmsInternal medicinehemic and lymphatic diseasesmedicineHumansStage (cooking)Sex DistributionAgedNeoplasm StagingProportional Hazards ModelsRetrospective StudiesAged 80 and overHepatologyStage I Gastric Cancerbusiness.industryHazard ratioSmokingGastroenterologyCancerEpstein-Barr Virus PositiveMiddle AgedOverweightUniversity hospitalmedicine.diseasePrognosisLatviaConfidence intervalSurvival Rate030220 oncology & carcinogenesis030211 gastroenterology & hepatologyFemaleNeoplasm Gradingbusiness
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