Search results for "UIC"
showing 10 items of 929 documents
Construcción de una escala de prejuicio percibido por inmigrantes latinoamericanos en España
2017
RESUMEN Esta tesis presenta el proceso de construcción, desarrollo y evaluación psicométrica de una escala de prejuicio percibido por inmigrantes latinoamericanos en España, la que se plantea desde la perspectiva de la amenaza grupal. La inmigración comenzó a incidir en el contexto español hace casi dos décadas. Este fenómeno se ha visto criticado por los nacionales debido al incremento de esta población y por la crisis socio-económica que vive el país desde el año 2008; lo que ha servido como argumento para justificar las actitudes prejuiciosas hacia el conglomerado extranjero. Diversos estudios han dado cuenta sobre cómo la percepción de amenaza con la que se aprecia a este exogrupo influ…
Estudio y modulación del metabolismo del glutatión en la tolerancia al estrés oxidativo generado por plaguicidas en organismos acuáticos de interés c…
2003
La utilización de plaguicidas para el cultivo del arroz en campos cercanos a humedales de gran valor ecológico como los Parques Naturales de la Albufera de Valencia y el Delta del Ebro (Tarragona) suponen un riesgo no sólo para los ecosistemas de estos Parques sino también para la pesca y acuicultura que se desarrolla en la zona. La anguila europea (Anguilla anguilla) reside en ambos hábitats y está expuesta a cantidades considerables de herbicidas tiocarbamatos como el molinato y tiobencarb. Estos plaguicidas disminuyen y oxidan los niveles del antioxidante intracelular más importante, el glutatión (GSH). Así, se ha descubierto que el principal mecanismo de toxicidad de los herbicidas tioc…
Il fine vita e il legislatore pensante. Il punto di vista dei comparatisti - Parte I
2021
Il saggio - nella parte riferibile all'Autore - si preoccupa di ricostruire la relazione fra cure palliative e aiuto al suicidio. L'attenzione è in particolare proiettata sulla descrizione dell'itinerario della sedazione palliativa allo scopo di ridurre la possibilità che lo stato avanzato della patologia induca il paziente a chiedere di porre fine alla propria vita ormai costellata da insopportabili sofferenze. L'indagine si articola lungo la valorizzazione, incoraggiata dallo studio comparatistico, della libertà di autodeterminazione.
Bergson, defensor de la sostenibilidad
2016
Este trabajo de investigación pone de manifiesto la vigencia de los planteamientos de Henri Bergson como crítico del modelo de globalización actual que trata como elementos de la misma naturaleza al tiempo y al espacio; una globalización en la que está ausente, en la que se ha ignorado el tiempo como duración. Bergson fue el filósofo que vio con claridad la diferencia sustancial entre tiempo y espacio, y la consiguiente no aplicabilidad de las leyes físicas a un tiempo que en realidad es irreversible, que prima sobre el espacio. Es pues de crucial importancia su intuición de la continuidad del tiempo, su concepción integral de la durée y de lo durable. El pensamiento de Bergson va en contra…
Fruits and vegetables protect against the genotoxicity of heterocyclic aromatic amines activated by human xenobiotic-metabolizing enzymes expressed i…
2010
Heterocyclic aromatic amines (HAAs) can be formed during the cooking of meat and fish at elevated temperatures and are associated with an increased risk for cancer. On the other hand, epidemiological findings suggest that foods rich in fruits and vegetables can protect against cancer. In the present study three teas, two wines, and the juices of 15 fruits and 11 vegetables were investigated for their protective effect against the genotoxic effects of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). To closely mimic the enzymatic activation of these HAAs in humans, genetically engineered V79 Chinese hamster fibroblasts were employed tha…
Effect on Orange Juice of Batch Pasteurization in an Improved Pilot-Scale Microwave Oven
2010
The effects on orange juice batch pasteurization in an improved pilot-scale microwave (MW) oven was evaluated by monitoring pectin methyl-esterase (PME) activity, color, carotenoid compounds and vitamin C content. Trials were performed on stirred orange juice heated at different temperatures (60, 70, 75, and 85 degrees C) during batch process. MW pilot plant allowed real-time temperature control of samples using proportional integrative derivative (PID) techniques based on the infrared thermography temperature read-out. The inactivation of heat sensitive fraction of PME, that verifies orange juice pasteurization, showed a z-value of 22.1 degrees C. Carotenoid content, responsible for sensor…
Effect of cytochrome P450 inhibitors (diethyl dithiocarbamate, ketoconazole and grapefruit juice) on the pharmacokinetics of all-trans-retinoic acid.
2004
Diethyl dithiocarbamate (DEDTC) has been reported to be a more powerful inhibitor of all-trans-retinoic acid (ATRA) in vitro metabolism than the well-established cytochrome P450 (CYP) inhibitor ketoconazole (KC). In recent years grapefruit juice (GJ) has been shown to be able to increase the oral bioavailability of several drugs by inhibiting intestinal CYP. This study investigated the in vivo effect of these CYP inhibitors on the pharmacokinetics of ATRA. The latter was administered to rats as a constant-rate intravenous (i.v.) infusion (0.48 mg h(-1) kg(-1)) during 10 h and orally (1.6 mg kg(-1)). DEDTC (320 mg kg(-1) x 2 i.v., 6.4 and 32 mg kg(-1) per os (p.o.)) did not change the ATRA c…
Le développement des villes moyennes de l’Ouest atlantique entre 1963 et 1982
2022
International audience
Il cammino indicato dalla Corte costituzionale per la disciplina del suicidio medicalmente assistito fra giurisprudenza di merito e perdurante attesa…
2021
The study aims to investigate the indicator path from the sentence of the Constitutional Court n. 242/2019 on medically assisted suicide. Pending the approval of the legislative discipline, on which Parliament is currently working, deemed necessary by the Constitutional Court itself to give certainty to such an ethically delicate matter, judges are increasingly finding themselves deciding on cases of medically assisted suicide and on the both on the level of criminal law and on the level of civil law, interpreting the constitutional jurisprudence on the subject in a constitutionally compliant
Grazoprevir/elbasvir for the immediate treatment of recently acquired HCV genotype 1 or 4 infection in MSM.
2020
Abstract Background In Europe, increases in HCV infection have been observed over the last two decades in MSM, making them a key population for recently acquired HCV. Alternative combinations of direct-acting antiviral agents against early HCV infection need to be assessed. Patients and methods In this pilot trial, MSM with recently acquired genotype 1 or 4 HCV infection were prospectively included and received 8 weeks of oral grazoprevir 100 mg and elbasvir 50 mg in a fixed-dose combination administered once daily. The primary endpoint was sustained virological response evaluated 12 weeks after the end of treatment (EOT) (SVR12). Secondary endpoints were the virological characterization of…