Search results for "ULB"
showing 10 items of 219 documents
Defective Postnatal Neurogenesis and Disorganization of the Rostral Migratory Stream in Absence of theVax1Homeobox Gene
2004
The subventricular zone (SVZ) is one of the sources of adult neural stem cells (ANSCs) in the mouse brain. Precursor cells proliferate in the SVZ and migrate through the rostral migratory stream (RMS) to the olfactory bulb (OB), where they differentiate into granule and periglomerular cells. Few transcription factors are known to be responsible for regulating NSC proliferation, migration, and differentiation processes; even fewer have been found to be responsible for the organization of the SVZ and RMS. For this reason, we studied the ventral anterior homeobox (Vax1) gene in NSC proliferation and in SVZ organization. We found thatVax1is strongly expressed in the SVZ and in the RMS and that,…
Postnatal Neurogenesis and Neuronal Regeneration
2004
The discovery of neurogenesis in the adult brain has challenged one of the central dogmas of neuroscience. Pioneer reports in rodents seed the ground for a detailed description in birds and reptiles, which was finally confirmed in discrete regions of several mammalian species including humans. This neurogenetical capability may serve as the basis for neuronal regeneration, as has already been described in the reptilian brain, and thus may represent a promising therapeutic approach. Consequently, in the last years there has been an important effort to deepen our knowledge of the biology, the functional significance and the regulation of adult neurogenesis.
Multipotent Neural Stem Cells Reside into the Rostral Extension and Olfactory Bulb of Adult Rodents
2002
The lateral walls of the forebrain lateral ventricles are the richest source of stem cells in the adult mammalian brain. These stem cells give rise to new olfactory neurons that are renewed throughout life. The neurons originate in the subventricular zone (SVZ), migrate within the rostral extension (RE) of the SVZ along the rostral migratory stream (RMS) within tube-like structures formed of glial cells, to eventually reach the olfactory bulb (OB). We demonstrate that, contrary to the current view, multipotential (neuronal-astroglial-oligodendroglial) precursors with stem cell features can be isolated not only from the SVZ but also from the entire RE, including the distal portion within the…
Estimating rainfall erosivity by aggregated drop size distributions
2016
Rainfall erosivity is defined as the potential of the rain to cause erosion, and it can be represented by rainfall kinetic power. At first in this paper, the raindrop size distributions (DSD) measured by an optical disdrometer located at Palermo in the period June 2006–March 2014 and aggregated for intensity classes, are presented. Then an analysis of raindrop size characteristics is carried out, and the reliability of Ulbrich's distribution, using both the maximum likelihood and momentum estimate parameter methods, is tested. The raindrop size measurements are used to determine the experimental rainfall kinetic power values, which are compared with the ones calculated by a theoretically de…
Gulbenes slēpošanas bāzes attīstības projekts
2018
Maģistra darba mērķis ir izstrādāt Gulbenes slēpošanas bāzes attīstības projektu, atbilstoši projektu vadīšanas metodoloģijai. Gulbenes slēpošanas bāzes attīstības projekts ir izstrādāts ar mērķi tā īstenošanas rezultātā nodrošināt Gulbenes slēpošanas bāzes lietošanas iespējas visa gada garumā, tādējādi sekmējot iedzīvotāju nodarbošanos ar fiziskām aktivitātēm svaigā gaisā. Projekta gala rezultātā ietilpst mākslīgā sniega trases izveidošanas nodrošināšana 1500 m garumā gada aukstajā laikā, kā arī nepieciešamā aprīkojuma nodrošināšana inventāra uzglabāšanai, ģērbtuvju un trases ofisa izveidošanai. Projekta kopējais ilgums paredzēts aptuveni 4 mēneši. Darbs sastāv no 89 lappusēm, 22 attēliem,…
Reward and punishment: investigating cortico-bulbar excitability to disclose the value of goods
2013
A continuing challenge for neuroscientists is to develop new conceptual tools and methodologies for understanding, predicting and modelling the influences of rewarding/punishing outcomes on human behaviour and decision making. Reinforcement shapes behaviours from the most primitive (fight/flight, ingest/regurgitate, approach/avoid) to complex (buy/sell). Understanding the neural processes underlying reinforcement is critical for understanding economic and social decision-making. Moreover, comprehension of deranged processing and responses to reinforcing stimuli is crucial across a range of psychology fields and society as a whole, including psychiatric and neurological illness, eating disor…
Paenibacillus larvae Chitin-Degrading Protein PlCBP49 Is a Key Virulence Factor in American Foulbrood of Honey Bees
2014
Paenibacillus larvae, the etiological agent of the globally occurring epizootic American Foulbrood (AFB) of honey bees, causes intestinal infections in honey bee larvae which develop into systemic infections inevitably leading to larval death. Massive brood mortality might eventually lead to collapse of the entire colony. Molecular mechanisms of host-microbe interactions in this system and of differences in virulence between P. larvae genotypes are poorly understood. Recently, it was demonstrated that the degradation of the peritrophic matrix lining the midgut epithelium is a key step in pathogenesis of P. larvae infections. Here, we present the isolation and identification of PlCBP49, a mo…
The "olfactostriatum" of snakes: a basal ganglia vomeronasal structure in tetrapods.
2005
The olfactostriatum is a portion of the basal ganglia of snakes situated ventromedially to the nucleus accumbens proper. It receives a major vomeronasal input from the nucleus sphericus, the primary target of accessory olfactory bulb efferents. Recently, the ophidian olfactostriatum has been characterized on the basis of chemoarchitecture (distribution of serotonin, neuropeptide Y and tyrosine hydroxylase) and hodology (afferent and efferent connections). In contrast to the nucleus accumbens proper, the olfactostriatum is densely immunoreactive for serotonin and neuropeptide Y and sparsely immunoreactive for tyrosine hydroxylase. The nucleus accumbens proper and the olfactostriatum share mo…
Arhitektūras mantojuma aizsardzība Gulbenes rajonā, 1967.-1991.gads
2018
Pētījumā aplūkoti Gulbenes rajona arhitektūras pieminekļu aizsardzības un izmantošanas aspekti no 1967. – 1991. gadam, kā arī sniegta informācija par LPSR attieksmi pret arhitektūras mantojuma aizsardzību. Minētā informācija attiecībā uz pieminekļu aizsardzību galvenokārt balstās uz Valsts kultūras pieminekļu aizsardzības inspekcijas pieminekļu dokumentācijas centra materiāliem. Darba mērķis ir izpētīt arhitektūras pieminekļu aizsardzību Gulbenes rajonā laika posmā no 1967. – 1991. gadam. Sākotnēji darbā tiek sniegta informācija par LPSR attieksmi un pārvaldi kultūras pieminekļu aizsardzības kontekstā. Turpinājumā tiek pievērsta uzmanība praktiskajai arhitektūras pieminekļu aizsardzībai Gul…
Exposición de la oliva bulbar mediante los abordajes far lateral y retrosigmoideo bajo. Análisis comparativo de la superficie expuesta y ángulo de at…
2021
A lo largo de la historia neuroquirúrgica, el tratamiento de lesiones intrínsecas localizadas en el tronco cerebral ha sido tema de mucha controversia. El tronco cerebral es la estructura anatómica del sistema nervioso central (SNC) que presenta mayor concentración de núcleos y fibras, y su simple manipulación puede conllevar importante morbi-mortalidad. El presente trabajo de investigación, se desarrolla teniendo en cuenta los conocimientos del tronco cerebral desarrollados por el Prof. Evandro de Oliveria. Una vez establecido uno de los puntos de entrada seguros a nivel bulbar, hemos querido evaluar el abordaje más seguro a la oliva bulbar (la principal zona de entrada segura a la región …