Search results for "UTC"

showing 10 items of 5408 documents

Efficacy of “Family Connections”, a program for relatives of people with borderline personality disorder, in the Spanish population: study protocol f…

2020

Abstract Background Patients with borderline personality disorder (BPD) experience significant affect regulation difficulties that cause serious consequences in their work, emotional, and social environments. This dysfunctional pattern also produces great suffering and a heavy burden on their relatives. Fortunately, some studies show that treatment of relatives of people with BPD begins to be important in the patients’ recovery and in improving family dynamics. One of the treatments that has obtained the most empirical support is Family connections (FC). This 12-session program is an adaptation of different Dialectical Behavior Therapy strategies. To test the efficacy of FC, five uncontroll…

relativescaregiverslcsh:RC435-571medicine.medical_treatmentDBTInterventionDysfunctional familyBurdenDialectical Behavior TherapyPersonality Disordersburdenlaw.inventionStudy ProtocolRandomized controlled triallawlcsh:PsychiatryIntervention (counseling)Family connectionsmedicineHumansBorderline personality disorderinterventionIntention-to-treat analysisbusiness.industrymedicine.diseasePersonality disordersRelativesDialectical behavior therapyClinical trialPsychiatry and Mental healthTreatment Outcomefamily connectionsCaregiversSpainBorderline personality disorderFamily Relationsbusinessborderline personality disorderClinical psychologyBMC Psychiatry
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Effects of Oral Supplementation with Myo-Inositol and D-Chiro-Inositol on Ovarian Functions in Female Long-Term Survivors of Lymphoma: Results from a…

2022

The progressive improvement of lymphoma treatment has led to an important prolongation of patient survival and life expectancy. The principal international scientific societies of oncology now therefore recommend that long-term survivors of lymphoma join fertility programs. Specifically, fertile-age patients should be assisted by a multidisciplinary team, including specialists dedicated to fertility preservation in oncology, in order to support the completion of their reproductive project. In the general population, the use of Myo-Inositol and D-Chiro-Inositol (MI/DCI) has been demonstrated to be an effective choice to treat ovarian dysfunctions, with a consequent improvement in reproductiv…

reproductive outcomesfertility preservationhealth promotionprecision medicineMedicine (miscellaneous)lymphomaprecision medicine; health promotion; Inositol; lymphoma; fertility preservation; reproductive outcomesSettore MED/40 - Ginecologia E OstetriciaInositolInositol; fertility preservation; health promotion; lymphoma; precision medicine; reproductive outcomesJournal of personalized medicine
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Maintenance of anticoagulant and antiplatelet agents for patients undergoing vitreoretinal surgery

2009

International audience; Purpose: To establish the prevalence of anticoagulant, aspirin, and clopidogrel use in patients undergoing vitreoretinal surgery, and to compare the outcome of peribulbar anesthesia between users and non-users. Materials and Methods: We conducted a retrospective case series in one academic center between January and June 2009. We analyzed the chart of 239 eyes who underwent posterior segment surgery with peribulbar anesthesia. Data included age, reasons for anticoagulant and/or antiplatelet agents, operative procedure, history of diabetes mellitus, high blood pressure, axial globe length, pre and post operative visual acuity, complications rates during and after anes…

retina[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologygenetic structures[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organsclinical (human) or epidemiologic studies: outcomes/complications[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organsvitreoretinal surgeryeye diseases[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Good clinical response, remission, and predictors of remission in rheumatoid arthritis patients treated with tumor necrosis factor-α blockers: The GI…

2007

OBJECTIVE: To assess the prevalence of good clinical response and remission in rheumatoid arthritis (RA) patients with longstanding disease treated with anti-tumor necrosis factor-alpha (TNF-alpha) drugs at outpatient clinics. METHODS: Retrospective national study of 14 academic tertiary referral rheumatology medical centers. RA patients with a Disease Activity Score (DAS28) > 3.2 were defined as having active disease and could start TNF-alpha blockers. All patients received one TNF-alpha blocker plus methotrexate (10-20 mg/wk). At the third month the patients were categorized as responders or nonresponders, based on improvement of at least 0.25 of the Health Assessment Questionnaire (HAQ).…

rheumatoid arthritisAdultMaleQuality Assurance Health Carepredictors of remissionTumor Necrosis Factor blockersAntibodies Monoclonal HumanizedSeverity of Illness IndexReceptors Tumor Necrosis FactorEtanerceptArthritis RheumatoidRheumatoid arthritis; Good clinical response; Tumor Necrosis Factor blockersPredictive Value of TestsHumansRheumatoid arthritispredictors of remission; rheumatoid arthritis; tumor necrosis factor-alpha blockersAgedRetrospective StudiesGood clinical responseTumor Necrosis Factor-alphatumor necrosis factor-alpha blockersRemission InductionAdalimumabAntibodies MonoclonalMiddle AgedPrognosisInfliximabLogistic ModelsMethotrexateTreatment Outcomedisability score; good clinical response; remission; rheumatoid arthritis; tumor necrosis factor-α blockersItalyAntirheumatic AgentsImmunoglobulin GFemale
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Etanercept maintains the clinical benefit achieved by infliximab in patients with rheumatoid arthritis who discontinued infliximab because of side ef…

2007

Objective: To evaluate the efficacy of switching to etanercept treatment in patients with rheumatoid arthritis who already responded to infliximab, but presented side effects. Methods: Charts of 553 patients with rheumatoid arthritis were retrospectively reviewed to select patients who responded to the treatment with infliximab and switched to etanercept because of occurrence of adverse effects. Clinical data were gathered during 24 weeks of etanercept treatment and for the same period of infliximab treatment before infliximab was stopped. Disease Activity Score computed on 44 joints (DAS-44), erythrocyte sedimentation rate (ESR) 1st hour, Visual Analogue Scale (VAS) of pain, Health Assessm…

rheumatoid arthritisMaleConcise ReportArthritisGastroenterologyReceptors Tumor Necrosis FactorEtanerceptEtanerceptArthritis Rheumatoidimmune system diseasesImmunology and AllergyHealth Status Indicatorsskin and connective tissue diseasesmedicine.diagnostic_testbiologyAntibodies MonoclonalMiddle AgedC-Reactive ProteinTreatment OutcomeBiologic agents; etanercept; infliximab; infusion reactionRheumatoid arthritisErythrocyte sedimentation rateAntirheumatic AgentsFemalemedicine.drugmusculoskeletal diseasesAdultmedicine.medical_specialtyVisual analogue scaleImmunologyBlood Sedimentationinfusion reactionGeneral Biochemistry Genetics and Molecular BiologyRheumatologyInternal medicinemedicineHumansAdverse effectRetrospective StudiesChi-Square Distributionbusiness.industryTumor Necrosis Factor-alphaC-reactive proteinetanercept; infliximab; rheumatoid arthritismedicine.diseaseInfliximabInfliximabSurgeryBiologic agentsstomatognathic diseasesImmunoglobulin Gbiology.proteinbusinessinfliximabetanercept
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Fosildiagénesis del anélido Rotularia spirulaea (Lamarck, 1818) (Polychaeta, Serpulidae) en el Eoceno del dominio pirenaico occidental

2018

The presence of the fossil polychaete Rotularia spirulaea (Lamarck, 1818) in Eocene deposits (middle Lutecian – upper Bartonian and (?) Priabonian) belonging to the western Pyrenean Domain is verified. In this paper, a fossildiagenetic study has been carried out. Fossils from three areas, corresponding to diff erent depositional settings, have been analysed. In area 1, sediments of the Ardanatz Sandstone and Ilundain Marls formations [Pamplona Basin and adjoining areas (Navarre)], were sampled. Here, the specimens of R. spirulaea  were not substantially affected by taphonomic reworking and the original microstructure of the carbonate tube is preserved. The test consists of a thick external …

rotularia spirulaea morphology fossildiagenesis paleogene pyrenees.CalciteRotulariafood.ingredientbiologyOutcropGeochemistryPaleontologybiology.organism_classificationQE701-760DiagenesisSedimentary depositional environmentForaminiferachemistry.chemical_compoundfoodchemistryMarlCarbonateGeologySpanish Journal of Palaeontology
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Safety and Tolerance Evaluation of Milk Fat Globule Membrane-Enriched Infant Formulas: A Randomized Controlled Multicenter Non-Inferiority Trial in H…

2014

ObjectiveThis multicenter non-inferiority study evaluated the safety of infant formulas enriched with bovine milk fat globule membrane (MFGM) fractions.MethodsHealthy, full-term infants ( n = 119) age ≤14 days were randomized to standard infant formula (control), standard formula enriched with a lipid-rich MFGM fraction (MFGM-L), or standard formula enriched with a protein-rich MFGM fraction (MFGM-P). Primary outcome was mean weight gain per day from enrollment to age 4 months (non-inferiority margin: –3.0 g/day). Secondary (length, head circumference, tolerability, morbidity, adverse events) and exploratory (phospholipids, metabolic markers, immune markers) outcomes were also evaluated.Res…

safetymedicine.medical_specialtyinfant feedingbusiness.industrygrowthGeneral Engineeringlcsh:RJ1-570lcsh:PediatricsGastroenterologyPrimary outcomeTolerabilityStandard infant formulaformula toleranceInternal medicineMedicineNon inferiority trialGlobules of fatmedicine.symptombusinessAdverse effectMilk fat globuleWeight gainBiomedical engineeringOriginal Researchmilk fat globule membraneClinical Medicine Insights: Pediatrics
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Serenoa repens, lycopene and selenium versus tamsulosin for the treatment of LUTS/BPH. An Italian multicenter double-blinded randomized study between…

2014

serenoa repensMaleProstatic HyperplasiaAntioxidantsSettore MED/24 - UrologiaSeleniumDouble-Blind MethodDrug TherapyLower Urinary Tract SymptomsSerenoa80 and overHumansBPH; LUTS; lycopene; phytotherapy; selenium; serenoa repens; tamsulosin; Aged; Aged 80 and over; Antioxidants; Carotenoids; Double-Blind Method; Drug Therapy Combination; Humans; Italy; Lower Urinary Tract Symptoms; Male; Middle Aged; Phytotherapy; Prostatic Hyperplasia; Quality of Life; Selenium; Serenoa; Sulfonamides; Treatment Outcome; Urodynamics; Urological AgentsAgedSulfonamidesLUTSphytotherapyMiddle AgedlycopeneCarotenoidsBPH LUTS lycopene phytotherapy selenium serenoa repens tamsulosinUrodynamicsTreatment OutcomeItalyBPHtamsulosinCombinationQuality of LifeUrological Agentsserenoa repens; lycopene; selenium; tamsulosin; LUTS; BPH; phytotherapy
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Omalizumab outcomes for up to 6 years in pediatric patients with severe persistent allergic asthma

2021

BACKGROUND: Various studies have assessed omalizumab outcomes in the clinical practice setting but follow-up and/or number of patients included were limited. We aim to describe the long-term outcomes of pediatric patients with severe persistent allergic asthma receiving omalizumab in the largest real-life cohort reported to date. METHODS: ANCHORS was a multicenter, observational, retrospective cohort study conducted in 25 Pediatric Allergy and Pulmonology units in Spain. We collected data of patients < 18 years and initiating omalizumab between 2006 and 2018, from the year prior to omalizumab initiation to discontinuation or last available follow-up. The primary outcome was the evolution of…

severe asthmamedicine.medical_specialtyPediatricsImmunology*real lifeOmalizumabhumanized monoclonal antibodiesOmalizumab*adolescentsAntibodies Monoclonal HumanizedAnti-asthmatic Agent03 medical and health sciences0302 clinical medicinechildrenreal lifeInternal medicinemedicine*anti-asthmatic agents*childrenHumansImmunology and AllergyChildren adolescents anti-asthmatic agents humanized monoclonal antibodies observational study omalizumab real-life severe asthmaAnti-Asthmatic Agentsadolescents030212 general & internal medicineChildAdverse effectRetrospective Studiesbusiness.industryasthmatic agents*observational studyanti&#8208Retrospective cohort studyAsthmaDiscontinuation*omalizumabTreatment OutcomePulmonology030228 respiratory system*humanized monoclonal antibodies*severe asthmaSevere persistent allergic asthmaPediatrics Perinatology and Child HealthCohortomalizumabobservational studyObservational studybusinessmedicine.drugPediatric Allergy and Immunology
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Editorial: Sex differences in cerebrovascular diseases

2023

sex differencespreventiontreatmentNeurologyoutcomeoutcome; prevention; sex differences; stroke; treatmentNeurology (clinical)strokeFrontiers in Neurology
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