Search results for "Uber"
showing 10 items of 1027 documents
Quantifying transmission fitness costs of multi-drug resistant tuberculosis.
2021
As multi-drug resistant tuberculosis (MDR-TB) continues to spread, investigating the transmission potential of different drug-resistant strains becomes an ever more pressing topic in public health. While phylogenetic and transmission tree inferences provide valuable insight into possible transmission chains, phylodynamic inference combines evolutionary and epidemiological analyses to estimate the parameters of the underlying epidemiological processes, allowing us to describe the overall dynamics of disease spread in the population. In this study, we introduce an approach to Mycobacterium tuberculosis (M. tuberculosis) phylodynamic analysis employing an existing computationally efficient mod…
[Epidemiology of paediatric tuberculosis today].
2003
Tuberculosis (TB) kills 2 million people each year in the world, of which 250,000 are children. In Italy, paediatric TB is 3.5% of total cases with a steady trend in the last ten years. Childhood tuberculosis remains a disease of great concern because its occurrence always indicates recent transmission and is a pivotal indicator of effectiveness of TB control efforts. The epidemiological study, including DNA fingerprinting, of 71 children affected by TB - 62 pulmonary, 9 meningitis, 2 renal-shows that the source case is frequently a parent or household member. Sensitivity to anti-tubercular drugs was tested for 18/20 isolates obtained from the children and 21/44 isolates obtained from infec…
Novel mechanism for the radiation-induced bystander effect: nitric oxide and ethylene determine the response in sponge cells.
2006
Until now the bystander effect had only been described in vertebrates. In the present study the existence of this effect has been demonstrated for the phylogenetically oldest metazoan phylum, the Porifera. We used the demosponge Suberites domuncula for the experiments in the two-chamber-system. The lower dish contained irradiated "donor" cells (single cells) and the upper dish the primmorphs ("recipient" primmorphs). The "donor" cells were treated with UV-B light (40 mJ/cm2) and 100 microM hydrogen peroxide (H2O2), factors that exist also in the natural marine aquatic environment of sponges; these factors caused a high level of DNA strand breaks followed by a reduced viability of the cells.…
2001
Background Ethylene is a widely distributed alkene product which is formed enzymatically (e.g., in plants) or by photochemical reactions (e.g., in the upper oceanic layers from dissolved organic carbon). This gaseous compound was recently found to induce in cells from the marine sponge Suberites domuncula, an increase in intracellular Ca2+ level ([Ca2+]i) and an upregulation of the expression of two genes, the potential ethylene-responsive gene, SDERR, and a Ca2+/calmodulin-dependent protein kinase.
Правовое и имущественное положеніе евангелическо-лютеранской церкви въ Курляндской губерніи
1914
Grāmatā izdošanas gads nav uzrādīts.
Eine Antwort auf "Eine Klage und eine Frage" des Herrn emeritierten Moskauschen General-Superintendenten C. Coßmann
1894
Atsevišķs novilkums no:"Rigaer Tageblatt", Nr. 84 und 85, 1894.
Sea Urchin Granuloma
2005
Sea urchin granuloma is a chronic focal response to the puncture of sea urchin spines, induced by the permanence of prickle remnants in the wound. Until recent years, it was thought to represent a foreign body reaction but, following the description, in 2001, of its several histologic forms, the spectrum of its likely pathogenetic mechanisms has widened to include the immune responses to different non-self antigens. Depending on individual reactivity, in most cases, a limited number of granulomas is observed, however numerous the punctures may be. We report a case with more than 200 lesions and a tuberculoid histologic pattern, indicative of an immune reaction.
Od bowaryzmu do globus histericus: głód idealnej miłości jako efekt edukacji kobiet w XIX wieku
2020
A woman made unhappy by her dreams of an ideal love is the main character of two novels belonging to the Realist/Positivist movement: Gustave Flauberts’s Madame Bovary (1857) and Eliza Orzeszkowa’s On the Niemen (1888). Emma Bovary and Emilia Korczyńska have been educated according to the same sentimental pattern; they both have an undue feeling of being much more sublime than their milieu where they cannot find a man of their dreams. This makes them suffer and drift apart from real life.
Ćwok, kiep i frajer, czyli postać głupiego męża we francuskiej prozie realistycznej i naturalistycznej
2017
The paper discusses the theme of a stupid husband in three texts of French Realism and Naturalism: a novel by Gustave Flaubert and two short stories by Emile Zola and Guy de Maupassant. The main reference for the analysis is a paper by Stefan Symotiuk who divides the category of “fools” into several subcategories, according to reasons and signs of their stupidity. In agreement with Symotiuk’s thought, Flaubert’s Charles Bovary can be considered as a “blockhead”, dull but always glad with himself; Zola’s Mr Chabre is a “dolt”, heavily thinking and likely to hoax; finally, Maupassant’s Mr Lantin is a “dupe”, easily cheated because unable to see things as they are. All the three characters can…