Search results for "Uber"

showing 10 items of 1027 documents

Okadaic Acid, an Apoptogenic Toxin for Symbiotic/Parasitic Annelids in the Demosponge Suberites domuncula

2006

ABSTRACT The role of okadaic acid (OA) in the defense system of the marine demosponge Suberites domuncula against symbiotic/parasitic annelids was examined. Bacteria within the mesohyl produced okadaic acid at concentrations between 32 ng/g and 58 ng/g of tissue (wet weight). By immunocytochemical methods and by use of antibodies against OA, we showed that the toxin was intracellularly stored in vesicles. Western blotting experiments demonstrated that OA also existed bound to a protein with a molecular weight of 35,000 which was tentatively identified as a galectin (by application of antigalectin antibodies). Annelids that are found in S. domuncula undergo apoptotic cell death. OA is one ca…

animal structuresAnnelidaMolecular Sequence DataApoptosismedicine.disease_causeApplied Microbiology and BiotechnologyMicrobiologychemistry.chemical_compoundOkadaic AcidInvertebrate MicrobiologymedicineAnimalsHumansMesohylAmino Acid SequenceSymbiosisGalectinAnnelidBacteriaEcologybiologyToxinOkadaic acidbiology.organism_classificationDNA-Binding ProteinsSuberites domunculachemistryBiochemistrySuberitesBacteriaTranscription FactorsFood ScienceBiotechnologySuberitesApplied and Environmental Microbiology
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Bruton tyrosine kinase-like protein, BtkSD, is present in the marine sponge Suberites domuncula.

2003

Sponges, the simplest and most ancient phylum of Metazoa, encode in their genome complex and highly sophisticated proteins that evolved together with multicellularity and are found only in metazoan animals. We report here the finding of a Bruton tyrosine kinase (BTK)-like protein in the marine sponge Suberites domuncula (Demospongiae). The nucleotide sequence of one sponge cDNA predicts a 700-aa-long protein, which contains all of the characteristic domains for the Tec family of protein tyrosine kinases (PTKs). The highest homology (38% identity, 55% overall similarity) was found with human BTK and TEC PTKs. Sponge PTK was therefore named BtkSD. Human BTK is involved in the maturation of B …

animal structuresDNA ComplementaryeducationMolecular Sequence DataHomology (biology)immune system diseaseshemic and lymphatic diseasesComplementary DNAGeneticsAgammaglobulinaemia Tyrosine KinaseBruton's tyrosine kinaseAnimalsHumansAmino Acid SequenceProtein kinase ACaenorhabditis elegansGeneCaenorhabditis elegansGeneticsbiologySequence Homology Amino AcidKinaseProtein-Tyrosine Kinasesbiology.organism_classificationPoriferaSuberites domunculaMutationbiology.proteinGenomics
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Early evolution of metazoan serine/threonine and tyrosine kinases: identification of selected kinases in marine sponges.

1997

The phylum Porifera (sponges) was the first to diverge from the common ancestor of the Metazoa. In this study, six cDNAs coding for protein-serine/threonine kinases (PS/TKs) are presented; they have been isolated from libraries obtained from the demosponges Geodia cydonium and Suberites domuncula and from the calcareous sponge Sycon raphanus. Sequence alignments of the catalytic domains revealed that two major families of PS/TK, the "conventional" (Ca(2+)-dependent) protein kinase C (PKC), the cPKC subfamily, as well as the "novel" (Ca(2+)-independent) PKC (nPKC), form two separate clusters. In each cluster, the sequence from S. raphanus diverges first. To approach the question about the or…

animal structuresSubfamilyDNA ComplementaryMolecular Sequence DataProtein Serine-Threonine KinasesEvolution MolecularSpecies SpecificityGeneticsAnimalsSycon raphanusAmino Acid SequenceCloning MolecularProtein kinase AMolecular BiologyEcology Evolution Behavior and SystematicsProtein kinase CPhylogenyProtein Kinase CCalcareous spongebiologySequence Homology Amino AcidKinaseProtein-Tyrosine Kinasesbiology.organism_classificationPoriferaSuberites domunculaBiochemistryTyrosine kinaseMolecular biology and evolution
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L'origine de toutes les altérations superficielles du tubercule de pomme de terre est-elle vraiment infectieuse?

2009

SPE communication orale, résumé; Deux essais en sol stérile testant le pouvoir pathogène des souches le plus fréquemment isolées et inoculées seules, et un essai en hydroponie testant l'effet de co-inoculations de 2 souches sur l'apparition des altérations ont été mis en place.

bactérietubercule[ SDV ] Life Sciences [q-bio]sclerotiumpotato disease[SDV]Life Sciences [q-bio]champignongale communebacteriumT-RFLP;potato disease;sclerotium;scab;séquençage ITS[SDV] Life Sciences [q-bio]sclérotesolanum tuberosumT-RFLPpomme de terrescabséquençage ITS
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A (1->3)-beta-D-glucan recognition protein from the sponge Suberites domuncula. Mediated activation of fibrinogen-like protein and epidermal growth f…

2004

Sponges (phylum Porifera) live in a symbiotic relationship with microorganisms, primarily bacteria. Until now, molecular proof for the capacity of sponges to recognize fungi in the surrounding aqueous milieu has not been available. Here we demonstrate, for the demosponge Suberites domuncula (Porifera, Demospongiae, Hadromerida), a cell surface receptor that recognizes (1--3)-beta-D-glucans, e.g. curdlan or laminarin. This receptor, the (1--3)-beta-D-glucan-binding protein, was identified and its cDNA analysed. The gene coding for the 45 kDa protein was found to be upregulated in tissue after incubation with carbohydrate. Simultaneously with the increased expression of this gene, two further…

beta-GlucansMolecular Sequence DataPinacodermGene Expression-BiochemistryDemospongeEpidermal growth factorComplementary DNALectinsAnimalsAmino Acid SequencePhosphorylationProtein PrecursorsGlucansHadromeridaPhylogenybiologyEpidermal Growth FactorFibrinogenbiology.organism_classificationRecombinant ProteinsPoriferaSuberites domunculaSpongeBiochemistryCarrier ProteinsTyrosine kinaseSequence Alignment
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First record of Icerya seychellarum and confirmed occurrence of Aulacaspis tubercularis (Hemiptera: Coccomorpha) in Italy

2020

The Seychelles scale, Icerya seychellarum (Westwood, 1855) (Hemiptera: Coccomorpha: Monophlebidae), is reported for the first time in Italy. Moreover, the occurrence of the white mango scale, Aulacaspis tubercularis (Newstead, 1906) (Hemiptera: Coccomorpha: Diaspididae), firstly reported in 1990 on mango trees growing outdoors in a nursery near Milazzo (Messina province, Sicily), and then intercepted in 2013 on mango plants imported from Florida (USA) to the Botanical Garden in Padova (Italy), is confirmed. Both species were found in two Sicilian mango orchards located in the province of Messina. Their introduction is most likely due to the orchards planting using infested mango nursery pla…

biologyAulacaspis tubercularisPlant Sciencebiology.organism_classificationDiaspididaeHemipteralanguage.human_languageSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeHorticultureSettore AGR/11 - Entomologia Generale E ApplicataInsect ScienceMango scalelanguageBotanical gardenMonophlebidaeIcerya seychellarumDiaspididae . Monophlebidae . Scale insects. Mangifera indicaSicilianPhytoparasitica
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Induction of DNA damage and expression of heat shock protein HSP70 by polychlorinated biphenyls in the marine sponge Suberites domuncula Olivi

1999

The effects of different polychlorinated biphenyls (PCBs) including toxic coplanar non-ortho (PCB77) and non-planar mono-ortho (PCB118) and di-ortho (PCB153) congeners on the extent of DNA damage as well as on the expression of heat shock protein 70 (HSP70) were investigated in the marine sponge Suberites domuncula Olivi (Porifera; Demospongiae). A time-dependent increase in the number of DNA single-strand breaks, expressed as strand scission factor (SSF), was found after injection of a single dose of 25 mu g of PCB 118 or PCB 153 per gram wet mass of S. domuncula, using Fast Micromethod assay, which is based on the unwinding of DNA under alkaline conditions. The number of strand breaks ind…

biologyDNA damageAquatic Sciencebiology.organism_classificationMolecular biologyMicrobiologyHsp70Suberites domunculaSpongechemistry.chemical_compoundDNA damage; heat shock protein hsp70; polychlorinated biphenyls; environmental stresschemistryHeat shock proteinGene expressionEcology Evolution Behavior and SystematicsDNASuberites
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Free and bound hydroxyl and carboxyl groups in the cutin of Quercus suber leaves

1984

Abstract The number of free and bound hydroxyl and carboxyl groups of the cutin of Quercus suber leaves was investigated by the lithium borohydride hydrogenolysis of mesyl-cutin compared with the lithium borohydride hydrogenolysis of untreated cutin. Fifty per cent of the vic -diol groups of the trihydroxy C 18 acid component and twenty five per cent of the secondary hydroxyl groups of the dihydroxy C 16 acid component are free. The rest of the secondary and all of the primary hydroxyl groups are esterified; all carboxyl groups are esterified.

biologyDiolfood and beveragesPlant ScienceGeneral MedicineQuercus suberCutinHorticulturebiology.organism_classificationBiochemistryMedicinal chemistrychemistry.chemical_compoundchemistryHydrogenolysisLithium borohydrideOrganic chemistryMolecular BiologyPhytochemistry
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Hydroquinone derivatives from the marine-derived fungus Gliomastix sp.

2017

Eight new hydroquinone derivatives, gliomastins A–D (1–4), 9-O-methylgliomastin C (5), acremonin A 1-O-β-D-glucopyranoside (6), gliomastin E 1-O-β-D-glucopyranoside (7), and 6′-O-acetyl-isohomoarbutin (8), together with seven known analogues were isolated from the marine-derived fungus Gliomastix sp. Their structures were elucidated by extensive spectroscopic analysis including 1D and 2D NMR measurements aided by DFT NMR calculations as well as MS data. TDDFT-ECD and OR calculations were performed to determine the absolute configurations of 1 and the aglycones of 6 and 7. Compound 1 features a novel skeleton, biogenetically derived from a Diels–Alder reaction between derivatives of 11 and 1…

biologyHydroquinone010405 organic chemistryStereochemistryGeneral Chemical EngineeringAlkaloidGliomastixGeneral ChemistryFungusbiology.organism_classification01 natural sciences0104 chemical sciencesMycobacterium tuberculosis010404 medicinal & biomolecular chemistrychemistry.chemical_compoundTermészettudományokchemistryIc50 valuesKémiai tudományokCytotoxicityTwo-dimensional nuclear magnetic resonance spectroscopyRSC Advances
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Induction of (2′−5′)oligoadenylate synthetase in the marine spongesSuberites domunculaandGeodia cydoniumby the bacterial endotoxin lipopolysaccharide

2002

Recent studies have shown that the Porifera, with the examples of the demosponges Suberites domuncula and Geodia cydonium, comprise a series of pathways found also in the immune system of Deuterostomia, such as vertebrates, but are absent in Protostomia, with insects or nematodes as examples. One pathway is the (2'-5')oligoadenylate synthetase [(2-5)A synthetase] system. In the present study we show that crude extracts from tissue of S. domuncula collected from the sea display a considerable amount of (2-5)A synthetase activity; 16% of the ATP substrate is converted to the (2-5)A product, while tissue from specimens which were kept for 6 months in an aquarium shows only 1% of conversion. As…

biologyLipopolysaccharide2'-5'-OligoadenylateStimulationbiology.organism_classificationAntimicrobialBiochemistryIn vitroMicrobiologyIncubation periodSuberites domunculachemistry.chemical_compoundImmune systemchemistryEuropean Journal of Biochemistry
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