Search results for "Uber"

First report of Cucumber mosaic virus infecting Solanum jasminoides in Italy

2008

Solanum jasminoides Paxton (potato vine or jasmine nightshade) is a vegetatively propagated ornamental species within the Solanaceae family. Recently, symptomless plants of this species were reported as natural hosts of the quarantine pest, Potato spindle tuber viroid (PSTVd) in Italy (1). In January 2008, approximately 1,000 potted, 2-year-old plants of S. jasminoides growing in an ornamental nursery in Sicily showed virus-like mosaic and malformation of leaves. Symptoms were observed on approximately 60% of the plants. Leaf tissue, collected from 30 symptomatic and 10 symptomless plants, was analyzed by double-antibody sandwich-ELISA with polyclonal antisera specific to Cucumber mosaic v…

Potentiation of the cytotoxic activity of copper by polyphosphate on biofilm-producing bacteria: A bioinspired approach

2012

Adhesion and accumulation of organic molecules represent an ecologically and economically massive problem. Adhesion of organic molecules is followed by microorganisms, unicellular organisms and plants together with their secreted soluble and structure-associated byproducts, which damage unprotected surfaces of submerged marine structures, including ship hulls and heat exchangers of power plants. This is termed biofouling. The search for less toxic anti-biofilm strategies has intensified since the ban of efficient and cost-effective anti-fouling paints, enriched with the organotin compound tributyltin, not least because of our finding of the ubiquitous toxic/pro-apoptotic effects displayed b…

BLAST Database with all accesible non-tuberculous mycobacteria genomic sequences (Oct, 2018)

2019

In our work "Towards next generation diagnostics for tuberculosis: identification of novel molecular targets by large-scale comparative genomics" (https://doi.org/10.1101/569384 ). We look for M. tuberculosis genes that are not present in organisms other tan MTBC. This database corresponds with the described database of 4,277 NTM assemblies.

Diabetes in active tuberculosis in low-income countries: to test or to take care?

2019

DETECTING TUBERCULIN SENSITIVITY

1982

Efectos del ácido valproico sobre el desarrollo sexual

2003

Introducción: La utilización del ácido valproico se ha relacionado enniñas y adolescentes con efectos adversos endocrinológicos: ganancia de peso e hiperandrogenismo. Además, enmujeres adultas se han descrito ovarios poliquísticos e hiperinsulinismo. En varones apenas se han estudiado losposibles efectos adversos endocrinológicos. Objetivos: El objetivo de este estudio fue evaluar los efectos del ácido valproico en el desarrollo puberal en chicas y en chicosepilépticos, en especial relación con su posible efecto hiperandrogénico. Material y métodos: Se incluyeron 23 chicas y 15 chicos (entre 8 y 16 años)epilépticos, tratados con ácido valproico, se compararoncon 15 niñas control y 10 niños …

Estudi de la plasticitat estructural en malalties psiquiàtriques amb models animals

2021

El concepte científic de l’estrès s’associa a una resposta adaptativa front a un estímul ambiental o una demanda. Tot i això, si les pertorbacions al medi ambient són constants, es produeix un desgast a l’organisme que té efectes perjudicials en aquest. El cervell es pot considerar l’òrgan central de l’estrès, ja que en ell comença la principal resposta biològica. És conegut que esdeveniments estressants de curta duració poden potenciar les funcions neuronals i millorar el rendiment cognitiu. D’altra banda, llargs períodes d’estrès poden alterar més profundament la fisiologia de diverses regions del sistema nerviós i afectar al seu funcionament, produint dèficits cognitius i d’aprenentatge.…

Biologically-induced transition of bio-silica sol to mesoscopic gelatinous flocs: a biomimetic approach to a controlled fabrication of bio-silica str…

2012

Siliceous sponges form their skeletal elements, the spicules, enzymatically via the sponge-specific enzyme silicatein. The enzymatic product of silicatein in vitro is a bio-silica polymer that is not processed/hardened by phase separation. In the present study we applied a two-phase system to investigate the transition of bio-silica, formed by silicatein, from the lucid state to the opaque/turbid state. We report for the first time that the polyether polyethylene glycol [PEG] causes a rapid transition of the lucid bio-silica to the opaque/turbid state. For the experiments the recombinant silicatein from the demosponge Suberites domuncula had been used. This process is rapid (1 h) and procee…

Silintaphin-1 - interaction with silicatein during structure-guiding bio-silica formation

2011

Silicateins are unique enzymes of sponges (phylum Porifera) that template and catalyze the polymerization of nanoscale silicate to siliceous skeletal elements. These multifunctional spicules are often elaborately shaped, with complex symmetries. They carry an axial proteinaceous filament, consisting of silicatein and the scaffold protein silintaphin-1, which guides silica deposition and subsequent spicular morphogenesis. In vivo, the synthesis of the axial filament very likely proceeds in three steps: (a) assembly of silicatein monomers to form one pentamer; (b) assembly of pentamers to form fractal-like structures; and finally (c) assembly of fractal-like structures to form filaments. The …

Molecular/chemical ecology in sponges. Evidence for an adaptive antibacterial response in Suberites domuncola

2004

Sponges (Porifera) represent the evolutionary oldest metazoan phylum still extant today. They have developed a complex Bauplan, based on the existence of structural and regulatory molecules; many of these have been cloned and analyzed in the past years. The demosponge Suberites domuncula has been used as a suitable model to demonstrate that these animals not only possess an adaptive immune response on the level of cytokines, but also, as pointed out here, on the level of synthesis of bioactive alkyl-lipid derivatives. From specimens of S. domuncula the two lyso-PAF (platelet-activating factor) compounds, 1-O-hexadecyl-sn-glycero-3-phosphocholine and 1-O-octadecyl-sn-glycero-3-phosphocholine…