Search results for "Ull"

Recensione a Il carme 67 di Catullo. Introduzione, edizione critica, traduzione e commento a cura di ORAZIO PORTUESE, Cesena, Stilgraf, 2013 (Quadern…

2015

Reviewed Work - Il carme 67 di Catullo, (Quaderni di «Paideia») by Orazio Portuese, Cesena 2013, pp. 420, ISBN 978-88-96240-39-7 Recensione a "Il carme 67 di Catullo", (Quaderni di «Paideia») a cura di Orazio Portuese, Cesena 2013, pp. 420, ISBN 978-88-96240-39-7

Liriche ed epigrammi

2015

Edizione critica, con traduzione italiana e note di commento, delle Nugae e degli Epigrammata di Gaio Valerio Catullo

La ‘tragedia’ del carme 64

2011

Gaio Valerio Catullo. Epithalamium Thetidis et Pelei

2003

Edizione critica di Catullo LXIV, con Introduzione, Traduzione e Note di commento

El Llibre de l'orde de cavalleria en el context sociocultural medieval

2010

Ramon Llull va redactar el seu Llibre de l’orde de cavalleria sota la influència d’un temps i d’una mentalitat fortament marcats pel context sociocultural medieval. L’article explica com cal entendre la realització d’aquesta obra en funció de l’etapa quaternària de l’Art lul·liana, amb les seves virtuts i els seus pecats; de la situació geopolítica del segle xiii, especialment tot allò relacionat amb la cavalleria, i dels tractats de cavalleria produïts o coneguts a la Corona d’Aragó de l’època.

Altered morphological and electrophysiological properties of Cajal-Retzius cells in cerebral cortex of embryonic Presenilin-1 knockout mice

2004

Mutations of Presenilin-1 are the major cause of familial Alzheimer's disease. Presenilin-1 knockout (PS1-/-) mice develop severe cortical dysplasia related to human type 2 lissencephaly. This overmigration syndrome has been attributed to the premature loss of Cajal-Retzius cells (CRcs), pioneer neurons required for the termination of radial neuronal migration. To elucidate the potential cellular mechanisms responsible for this premature neuronal loss, we investigated the morphological and electrophysiological properties of visually identified CRcs of wild-type (WT) and PS1-/- mouse brains at embryonic day 16.5. The density of CRcs was substantially reduced in the cerebral cortex of PS1-/-.…

Time-related changes in size of nuclei of pinealocytes in rats

1981

In a study of 96 adult male Sprague-Dawley rats, da- and time-related changes of the mean nuclear volume of pinealocytes were determined with the aim of testing the reproducibility of the karyometric findings described by Quay and Renzoni (1966). It is shown (i) that statistically significant differences exist between the central and peripheral mean volumes of pinealocyte nuclei/group of animals and time point (p less than 0.001), (ii) that the day and time related differences are statistically different in both regions (p less than 0.001), (iii) that in the center and periphery of the pineal body different diurnal patterns exist, and (iv) that the diurnal patterns are not parallel in the t…

An organogold compound as potential antimicrobial agent against drug resistant bacteria: Initial mechanistic insights

2021

Abstract The rise of antimicrobial resistance has necessitated novel strategies to efficiently combat pathogenic bacteria. Metal‐based compounds have been proven as a possible alternative to classical organic drugs. Here, we have assessed the antibacterial activity of seven gold complexes of different families. One compound, a cyclometalated Au(III) C^N complex, showed activity against Gram‐positive bacteria, including multi‐drug resistant clinical strains. The mechanism of action of this compound was studied in Bacillus subtilis. Overall, the studies point towards a complex mode of antibacterial action, which does not include induction of oxidative stress or cell membrane damage. A number …

Mast Cell–deficient KitW-sh “Sash” Mutant Mice Display Aberrant Myelopoiesis Leading to the Accumulation of Splenocytes That Act as Myeloid-Derived S…

2013

Abstract Mast cell-deficient KitW-sh “sash” mice are widely used to investigate mast cell functions. However, mutations of c-Kit also affect additional cells of hematopoietic and nonimmune origin. In this study, we demonstrate that KitW-sh causes aberrant extramedullary myelopoiesis characterized by the expansion of immature lineage-negative cells, common myeloid progenitors, and granulocyte/macrophage progenitors in the spleen. A consistent feature shared by these cell types is the reduced expression of c-Kit. Populations expressing intermediate and high levels of Ly6G, a component of the myeloid differentiation Ag Gr-1, are also highly expanded in the spleen of sash mice. These cells are …

Structural and regulatory functions of keratins.

2007

The diversity of epithelial functions is reflected by the expression of distinct keratin pairs that are responsible to protect epithelial cells against mechanical stress and to act as signaling platforms. The keratin cytoskeleton integrates these functions by forming a supracellular scaffold that connects at desmosomal cell-cell adhesions. Multiple human diseases and murine knockouts in which the integrity of this system is destroyed testify to its importance as a mechanical stabilizer in certain epithelia. Yet, surprisingly little is known about the precise mechanisms responsible for assembly and disease pathology. In addition to these structural aspects of keratin function, experimental e…