Search results for "Umana"
showing 10 items of 657 documents
Modifications of the vasopressin and ANP in the rat hypothalamic supraoptic nucleus during and after the physical exercise.
2009
ANP immunolocalization in internal carotid artery wall of subjects with and without atherosclerotic lesions
2008
ANP and insulin presence in human foetal pancreas
2009
Aim of this work is to investigate the presence of Atrial natriuretic peptide (ANP) and insulin in human foetal pancreas from not diabetic and diabetic mothers. The data literature evidenced that relationship between serum ANP and insulin. This work carried out on the sections immunostained for ANP and nsulin showed positivity for ANP and insulin in beta-cells of pancreas from diabetic mothers, while positivity for insulin in beta-cells of foetuses from not diabetic mothers. Results indicate that the insulin presence stimulates the ANP synthesis in pancreas of human foetuses from diabetic mothers. Aim of this work is to investigate the presence of Atrial natriuretic peptide (ANP) and insuli…
Immunolocalization of ANP and insulin in pancreas of human foetuses from diabetic mothers.
2009
Curcumin-Like Compounds as Neuroprotective Agents: Interactions with HSP60 and Amyloid Beta Peptide
2014
Alzheimer’s Disease (AD) represents a fundamental challenge for public health in the 21st century. Current AD therapies largely focus on symptomatic aspects of the clinical pathology, but they have yet to demonstrate any major impact on the disease progression [1]. The most important role of the research aimed at fighting the AD is the development of neuro-protective agents, able to interfere with the protein aggregation process whose clinical signature is represented by the plaques deposition. An important role in AD’s framework could be played by Heat shock proteins (HSPs), highly regulated proteins that mediate the proteins proper folding and promote recovery of their native conformation…
NEUROINFLAMMATION AND SYNAPTIC IMBALANCE IN ALZHEIMER’S DISEASE
2020
THE ROLE OF HSP60 IN AMYLOID BETA PATHWAY: RELEVANCE TO ALZHEIMER’S DISEASE
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder affecting more than 40 million individuals worldwide. The high number of factors triggering the onset of AD justifies the current absence of disease-modifying therapies. The involved pathological mechanisms are still elusive and, therefore, the finding of effective therapies requires further elucidation of biomolecular mechanisms controlling AD pathogenesis. Particularly, the aberrant amyloidogenic cleavage of amyloid precursor protein (APP), amyloid beta (Aβ) peptide misfolding and oligomerization, and the impairment of the protein quality control machinery are key hallmarks characterizing the onset of the disease. Furthe…