Search results for "Unio"

Worldwide research output trends on drinking and driving from 1956 to 2015.

2020

This study seeks to analyze worldwide research activity on drinking and driving of macro-actors (countries and research fields) and meso-actors (institutions, journals, articles, co-substance(s) studied) during the last 6 decades (between 1956 and 2015). Web of Science and Elsevier Scopus were searched using terms referred to drinking and driving, including terms related to vehicles and way spaces. Overlapping was excluded and absence of false positives was confirmed. Articles on alcohol with/without other psychoactive substances were assessed quantitatively (bibliometric measures). Well identified by All Science Journal Classification system (ASJC) (Elsevier Scopus), an increase in the num…

Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.

2015

Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different cell types and participate in physiological and pathophysiological processes. EVs mediate intercellular communication as cell-derived extracellular signalling organelles that transmit specific information from their cell of origin to their target cells. As a result of these properties, EVs of defined cell types may serve as novel tools for various therapeutic approaches, including (a) anti-tumour therapy, (b) pathogen vaccination, (c) immune-modulatory and regenerative therapies and (d) drug delivery. The translation of EVs into clinical therapies requires the categorization of EV-based therapeutics …

A CASCADE of effects of bisphenol A

2009

International audience

La fin de la transparence ?

2023

Statistical Learning Algorithms to Forecast the Equity Risk Premium in the European Union

2018

With the explosion of “Big Data”, the application of statistical learning models has become popular in multiple scientific areas as well as in marketing, finance or other business disciplines. Nonetheless, there is not yet an abundant literature that covers the application of these learning algorithms to forecast the equity risk premium. In this paper we investigate whether Classification and Regression Trees (CART) algorithms and several ensemble methods, such as bagging, random forests and boosting, improve traditional parametric models to forecast the equity risk premium. In particular, we work with European Monetary Union data for a period that spans from the EMU foundation at the begin…

The border effect in Spain: The Basque Country case

2006

Gil-Pareja S., Llorca-Vivero R. and Martinez-Serrano J. A. (2006) The border effect in Spain: the Basque Country case, Regional Studies 40, 335–345. This paper investigates the border effect on the Basque Country's trade, using a sample of 28 Organization for Economic Co-operation and Development (OECD) countries between 1995 and 2001. The results indicate that after controlling for market size and distance, the Basque Country trades between 12 and 16 times more with the rest of Spain than it does with any other country. The Spanish bias is lower in the case of the Basque Country's exports than in the case of imports. With respect to the time evolution, the results show a downward trend. Th…

A Differentiated European Union

2020

Differentiation in the EU has substantially increased. It does not only refer to instances of (differentiation in) integration, but also (potential) disintegration. Differentiation can often be causally traced back to crises, yet it should not be equated with ‘crisis’. However, the literature has only scarcely discussed the putative link between crisis and differentiated integration. Fundamentally, demands for differentiation need to be treated as both a cause and an effect of integration. Thus, differentiation should be acknowledged as a persistent feature of European integration. The chapter discusses the development of differentiation in European integration and reflects upon the scholar…

Budesonide/formoterol maintenance and reliever therapy: a new treatment approach for adult patients with asthma.

2007

An inhaled corticosteroid (ICS) or an ICS/long-acting beta(2)-agonist (LABA) combination plus short-acting beta(2)-agonist (SABA) as needed for symptom relief is recommended for persistent asthma. Additionally, budesonide/formoterol maintenance and reliever therapy (Symbicort SMART, AstraZeneca, Sweden) has been approved for adults in the European Union. This option is well tolerated and offers greater reductions in asthma exacerbations together with similar improvements in daily symptom control, at a lower overall steroid load, compared with fixed-dose ICS/LABA plus SABA.Two large clinical trials investigated the use of budesonide/formoterol as maintenance and reliever compared with medium…

L’autonomia di spesa delle Regioni fra Stato ed Unione europea dalla l. cost. 3/2001 alle condizionalità europee sulla ripresa e la resilienza

2021

L'articolo ricostruisce la tendenza all’accentramento nel governo delle finanze pubbliche e l’eccessiva distanza fra testo costituzionale e diritto costituzionale vivente per analizzare l'attuazione del Recovery Plan (PNRR) rilevando un ulteriore tendenza all’accentramento del governo della spesa. Si indagano dunque le ragioni della compressione dell’autonomia finanziaria di spesa per effetto del principio di indifferenza e del “doppio intreccio federale”. Si mira a inquadrare il tema alla luce della leale collaborazione e dellala resilienza istituzionale per accorciare la “distanza” fra testo costituzionale ed attuazione costituzionale in tema di autonomia di spesa delle Regioni. Si prospe…

The European Standards for Energy Efficiency in Buildings: an analysis of the Evolution with Reference to a Case Study

2019

The improvement of the energy efficiency of building stocks represents an important contribution for the reduction of the energy consumption in the European Union (EU), along with the decrease of greenhouse gases emissions. In this aim both the public administrations and the technical experts need reliable calculation methodology to assess buildings’ energy performance. In this framework, despite the recent publication of the Standard EN ISO 52016, that deeply modifies the approach to the energy building simulation by introducing a new hourly dynamic calculation model, the current normative framework (EN ISO 13790) will maintain its validity until the incorporation of the new Standard in th…