Search results for "Unity"
showing 10 items of 3852 documents
Antimitochondrial antibody -M2 positive autoimmune hepatitis during standard of care for chronic hepatitis C
2012
The current standard of care (SoC) for chronic hepatitis C, i.e. the combination of a pegylated-interferon (PEG-IFN) with ribavirin (RBV), may activate underlying autoimmune conditions. Particularly, interferon (IFN) has been known to induce or exacerbate autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) in hepatitis C virus patients. We describe a severe, acute-onset antimitochondrial antibody (AMA)-M2 positive AIH appearing during the last weeks of SoC in a woman with chronic hepatitis C and no previous history of autoimmunity, and resolving on protracted steroids. In this context, the relevance of the characterization of the immunoglobulin isotype of portal plasma cells for …
Suppression of murine experimental autoimmune hepatitis by T-cell vaccination or immunosuppression
1998
Patients with autoimmune hepatitis (AIH) usually require immunosuppressive therapy for many years, if not for a lifetime. Experimental immunotherapy such as T-cell vaccination aims at manipulating the immune system in such a way that autoimmunity is specifically regulated to enable long-lasting correction of the disease process. We aimed to test the feasibility of T-cell vaccination as well as conventional immunosuppression in the murine model of experimental autoimmune hepatitis (EAH). EAH was induced in 5- to 7-week-old BALB/c mice by immunization with syngeneic liver homogenate in complete Freund's adjuvant. For T-cell vaccination, splenocytes were removed from animals 14 days after indu…
Infection of Soybean Plants with the Insect Bacterial Symbiont Burkholderia gladioli and Evaluation of Plant Fitness
2017
To investigate the establishment and consequences of host-microbe interactions, it is important to develop controlled infection assays suitable for each system, as well as appropriate methods to evaluate successful infection and its associated effects. Here, we describe a procedure for bacterial inoculation of soybean plants, followed by the assessment of systemic infection and impact on plant fitness. Soybean (Glycine max) seedlings were mechanically wounded using a device that mimics insect herbivory and inoculated with known cell numbers of Burkholderia gladioli bacteria previously isolated from an insect host. The impact on the plants was evaluated by monitoring changes in height, time …
La construcción de la instersubjetividad desde la hermenéutica trascendental
2017
En este artículo se busca reflexionar sobre cómo el diálogo es una poderosa herramienta para utilizar en aquellos programas educativos que deseen contribuir con la transformación de la sociedad. Es por ello, que se hace necesario vincular la hermenéutica a la praxis de las ciencias sociales. La hermenéutica puede brindar a las ciencias sociales una metodología de encuentro de perspectivas a través de la intersubjetividad. La intersubjetividad, establecida a través del diálogo, puede posibilitar espacios de acercamiento a la hora de construir un conocimiento colectivo en el ámbito educativo. La ética, también como disciplina filosófica, puede servir para fundamentar la praxis educativa orien…
Heterogeneous nuclear ribonucleoprotein (hnRNP) F is a novel component of oligodendroglial RNA transport granules contributing to regulation of myeli…
2011
Myelin basic protein (MBP) is a major component of central nervous system (CNS) myelin. The absence of MBP results in the loss of almost all compact myelin in the CNS. MBP mRNA is sorted into RNA granules that are transported to the periphery of oligodendrocytes in a translationally inactive state. A central mediator of this transport process is the trans-acting factor heterogeneous nuclear ribonucleoprotein (hnRNP) A2 that binds to the cis-acting A2-response element in the 3′UTR of MBP mRNA. Recently, we found that activation of the Src family nonreceptor tyrosine kinase Fyn in oligodendrocytes leads to phosphorylation of hnRNP A2 and to increased translation of MBP mRNA. Here, we identify…
Sensitivity of the Cherenkov Telescope Array to emission from the gamma-ray counterparts of neutrino events
2021
We investigate the possibility of detection of the VHE gamma-ray counterparts to the neutrino astrophysical sources within the Neutrino Target of Opportunity (NToO) program of CTA using the populations simulated by the FIRESONG software to resemble the diffuse astrophysical neutrino flux measured by IceCube. We derive the detection probability for different zenith angles and geomagnetic field configurations. The difference in detectability of sources between CTA-North and CTA-South for the average geomagnetic field is not substantial. We investigate the effect of a higher night-sky background and the preliminary CTA Alpha layout on the detection probability.
Evaluating Multiple Polylogarithm Values at Sixth Roots of Unity up to Weight Six
2017
We evaluate multiple polylogarithm values at sixth roots of unity up to weight six, i.e. of the form $G(a_1,\ldots,a_w;1)$ where the indices $a_i$ are equal to zero or a sixth root of unity, with $a_1\neq 1$. For $w\leq 6$, we present bases of the linear spaces generated by the real and imaginary parts of $G(a_1,\ldots,a_w;1)$ and present a table for expressing them as linear combinations of the elements of the bases.
Towards the european strategy for particle physics: The briefing book
2007
This document was prepared as part of the briefing material for the Workshop of the CERN Council Strategy Group, held in DESY Zeuthen from 2nd to 6th May 2006. It gives an overview of the physics issues and of the technological challenges that will shape the future of the field, and incorporates material presented and discussed during the Symposium on the European Strategy for Particle Physics, held in Orsay from 30th January to 2nd February 2006, reflecting the various opinions of the European community as recorded in written submissions to the Strategy Group and in the discussions at the Symposium.
The $q$-calculus for generic $q$ and $q$ a root of unity
1996
The $q$-calculus for generic $q$ is developed and related to the deformed oscillator of parameter $q^{1/2}$. By passing with care to the limit in which $q$ is a root of unity, one uncovers the full algebraic structure of ${{\cal Z}}_n$-graded fractional supersymmetry and its natural representation.
What do dental college clinicians know about oral cancer and its risk factors?: An assessment among final year students, interns and faculty members …
2018
Background: The ability of health care professionals to perform oral cancer examination depends partly on their knowledge of the disease and its risk factors. This study aimed to assess and compare the knowledge of final year students, interns and faculty members regarding oral cancer and its risk factors.Material and Methods: A 35-item questionnaire about knowledge of oral cancer and its risk factors was distributed among participants from Jazan University's Dental School. A minimum score of 18 was the cut-off point for an acceptable total score of oral cancer knowledge [OCTS]. Descriptive statistics described the relations between demographics variables and knowledge levels of participant…