Search results for "Univariate"
showing 10 items of 300 documents
Is extracapsular nodal extension in sentinel nodes a predictor for nonsentinel metastasis and is there an impact on survival parameters?-A retrospect…
2016
The Z0011 trial has fundamentally changed axillary management in breast cancer patients. However, some important questions remain, like the role of extracapsular nodal extension (ENE) in positive sentinel nodes and the need for further axillary treatment. In this retrospective cohort study, we reviewed and analyzed data from 342 clinically node negative (cN0) breast cancer patients with a positive sentinel node and subsequent axillary lymph node dissection (ALND) from the BRENDA data base. The 104 (30.4%) ENE positive patients had a significantly higher proportion of ≥3 positive axillary lymph nodes (65.0%) compared to ENE negative patients with a positive sentinel node (21.4%). Likewise, E…
Multivariate independent prognostic factors in endometrial carcinoma: A clinicopathologic study in 181 patients: 10 years experience at the Departmen…
2003
The aim of this study was to evaluate the biologic outcome of endometrial carcinomas as compared to clinical and pathologic parameters and to identify multivariate independent prognostic factors. Charts were abstracted from patients with endometrial carcinoma from 1985 to 1995. Data on clinicopathologic variables, adjuvant treatment, site of recurrence, and survival were collected. chi2 test was used to test association between variables. Kaplan-Maier method was used for survival analysis and Cox proportional hazards model for multiple regression analysis. Univariate analysis revealed that FIGO stage, tumor grade, depth of myometrial invasion, biochemical analysis of progesterone receptor s…
Systemic, environmental and lifestyle risk factors for dry eye disease in a mediterranean caucasian population
2022
Abstract Objectives To assess systemic, environmental and lifestyle risk factors for dry eye disease (DED) in a Mediterranean Caucasian population. Methods A cross-sectional study was performed on 120 Caucasian participants aged between 18 and 89 years (47.0 ± 22.8 years). Medical history, information regarding environmental conditions and lifestyle, Ocular Surface Disease Index, Dry Eye Questionnaire-5, non-Invasive (Oculus Keratograph 5 M) breakup time, tear film osmolarity and ocular surface staining parameters were assessed in a single clinical session to allow DED diagnosis based on the guidelines of the Tear Film and Ocular Surface Society Dry Eye Workshop II Diagnostic Methodology Re…
Simplified criteria for the diagnosis of autoimmune hepatitis
2008
Diagnosis of autoimmune hepatitis (AIH) may be challenging. However, early diagnosis is important because immunosuppression is life-saving. Diagnostic criteria of the International Autoimmune Hepatitis Group (IAIHG) were complex and purely meant for scientific purposes. This study of the IAIHG aims to define simplified diagnostic criteria for routine clinical practice. Candidate criteria included sex, age, autoantibodies, immunoglobulins, absence of viral hepatitis, and histology. The training set included 250 AIH patients and 193 controls from 11 centers worldwide. Scores were built from variables showing predictive ability in univariate analysis. Diagnostic value of each score was assesse…
Changes in Treatment of Very Elderly Patients Six Weeks after Discharge from Geriatrics Department
2020
We assessed the prescriptions of patients hospitalized in a geriatric unit and subsequently discharged. This prospective and observational study was conducted over a two-month period in the geriatrics department (acute and rehabilitation units) of a university hospital. Patients discharged from this department were included over a two-month period. Prescriptions were analyzed at admission and discharge from the geriatrics department (DGD), and six weeks after DGD. We included 209 patients, 63% female, aged 86.8 years. The mean number of medications prescribed was significantly higher at DGD than at admission (7.8 vs. 7.1, p = 0.003). During hospitalization, 1217 prescriptions were changed (…
The Bernstein Basis and its applications in solving geometric constraint systems
2012
International audience; This article reviews the properties of Tensorial Bernstein Basis (TBB) and its usage, with interval analysis, for solving systems of nonlinear, univariate or multivariate equations resulting from geometric constraints. TBB are routinely used in computerized geometry for geometric modelling in CAD-CAM, or in computer graphics. They provide sharp enclosures of polynomials and their derivatives. They are used to reduce domains while preserving roots of polynomial systems, to prove that domains do not contain roots, and to make existence and uniqueness tests. They are compatible with standard preconditioning methods and fit linear program- ming techniques. However, curre…
Statistical methods for the comparison of measurements derived from orthodontic imaging
2000
Biometric comparison procedures for dental imaging methods with continuous outcome were reviewed, mainly concentrating on assessment and comparison of accuracy and precision according to the study design. Univariate graphical and numerical representations of corresponding deviations were summarized to derive a 'check list' of minimum information necessary to compare the measurement methods. The methods reviewed in this investigation are illustrated by the comparison of conventional (radiographic) cephalometry versus assessment using the DigiGraph in 50 female children. A paired t-test and the corresponding confidence interval approach were used to assess deviations in location of two imagin…
Seasonal precipitation interpolation at the Valencia region with multivariate methods using geographic and topographic information
2009
The spatial pattern of precipitation is a complex variable that strongly depends on other geographic and topographic factors. As precipitation is usually known only at certain locations, interpolation procedures are needed in order to predict this variable in other regions. The use of multivariate interpolation methods is usually preferred, as secondary variables—generally derived using GIS tools—correlated with precipitation can be included. In this paper, a comparative study on different univariate and multivariate interpolation methodologies is presented. Our study area is centred in the region of Valencia, located to the eastern Spanish Mediterranean coast. The followed methodology can …
Slope units-based flow susceptibility model: using validation tests to select controlling factors
2011
A susceptibility map for an area, which is representative in terms of both geologic setting and slope instability phenomena of large sectors of the Sicilian Apennines, was produced using slope units and a multiparametric univariate model. The study area, extending for approximately 90 km2, was partitioned into 774 slope units, whose expected landslide occurrence was estimated by averaging seven susceptibility values, determined for the selected controlling factors: lithology, mean slope gradient, stream power index at the foot, mean topographic wetness index and profile curvature, slope unit length, and altitude range. Each of the recognized 490 landslides was represented by its centroid po…
Bivariate nonlinear prediction to quantify the strength of complex dynamical interactions in short-term cardiovascular variability.
2005
A nonlinear prediction method for investigating the dynamic interdependence between short length time series is presented. The method is a generalization to bivariate prediction of the univariate approach based on nearest neighbor local linear approximation. Given the input and output series x and y, the relationship between a pattern of samples of x and a synchronous sample of y was approximated with a linear polynomial whose coefficients were estimated from an equation system including the nearest neighbor patterns in x and the corresponding samples in y. To avoid overfitting and waste of data, the training and testing stages of the prediction were designed through a specific out-of-sampl…