Search results for "Univers"

showing 10 items of 6284 documents

Lipidomics reveals altered biosynthetic pathways of glycerophospholipids and cell signaling as biomarkers of the polycystic ovary syndrome

2017

// Mariona Jove 1, * , Irene Pradas 1, * , Alba Naudi 1, * , Susana Rovira-Llopis 2 , Celia Banuls 2 , Milagros Rocha 2 , Manuel Portero-Otin 1 , Antonio Hernandez-Mijares 2, 3, 4, # , Victor M. Victor 2, 5, # and Reinald Pamplona 1, # 1 Department of Experimental Medicine, Lleida University-Institute for Research in Biomedicine of Lleida (UdL-IRBLleida), 25198 Lleida, Spain 2 Foundation for the Promotion of Healthcare and Biomedical Research in the Valencian Community (FISABIO), Service of Endocrinology, University Hospital Dr. Peset, 46017 Valencia, Spain 3 Fundacion Investigacion Hospital Clinico Universitario/INCLIVA, Valencia University, 46010 Valencia, Spain 4 Department of Medicine, …

0301 basic medicineOncologyCell signaling moleculesmedicine.medical_specialtyCell signalingGlycerophospholipidsDiseaseGlycerophospholipidsFree fatty acidsValencian community03 medical and health sciences0302 clinical medicineInternal medicineLipidomicsmedicinelipid de novo biosynthesisglycerophospholipids030219 obstetrics & reproductive medicinebusiness.industryfree fatty acidsLipidomeUniversity hospitalPolycystic ovary030104 developmental biologyOncologyLipidomicscell signaling moleculeslipidomicsbusinessResearch PaperOncotarget
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The effect of pre-cure bracket movement on shear bond strength during placement of orthodontic brackets, an in vitro study

2017

Background The purpose of this study was to determine the influence of linear and rotational pre-cure bracket displacement during the bonding procedure on shear bond strength (SBS) of orthodontic brackets. Material and Methods Stainless steel orthodontic premolar brackets were bonded to the buccal surfaces of 50 human pre-molars with a conventional two-step bonding protocol. Extracted human pre-molars were divided into 5 groups (n=10/group). In the Control Group, the brackets were bonded with no pre-cure bracket displacement or rotation. The Rotation Group was bonded with 45 degrees of pre-cure rotation. The Displacement Group was bonded with 2mm pre-cure linear displacement. The Rotation-D…

0301 basic medicineOrthodonticsUniversal testing machineMaterials scienceBracket:CIENCIAS MÉDICAS [UNESCO]Shear bond03 medical and health sciencesOrthodontic brackets030104 developmental biologymedicine.anatomical_structureUNESCO::CIENCIAS MÉDICASPremolarmedicineIn vitro studySlippageGeneral DentistryRotation group SO
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Elongated styloid process: An epidemiological study on digital panoramic radiographs

2017

Background The styloid process is a projecton of the temporal bone, its lenght is between 20 to 30 mm, when it is longer than 30 mm it is defined elongated styloid process. The aim of this study is an epidemiological evaluation of 1003 digital panoramic radiographs in an Italian population between 5 and 90 years old. Material and methods This is a retrospective analysis and the radiographs were selected from the Complex Operating Unit of Dentistry of Padua University Hospital database. The radiographs were performed using a Sirona Ortophos XG and the styloid process length was measured using the measuring tool of Sidexis Software. It was measured from the point where it left the temporal bo…

0301 basic medicinePanoramic radiographEpidemiological studyPanoramic radiographRadiographyEagle's syndrome; Elongated styloid process; Epidemiological study; Panoramic radiograph; Dentistry (all)03 medical and health sciences0302 clinical medicineTemporal boneRetrospective analysisMedicineGeneral DentistryProcess (anatomy)OrthodonticsEagle's syndromeOral Medicine and Pathologybusiness.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Elongated styloid processUniversity hospitalItalian populationUNESCO::CIENCIAS MÉDICASDentistry (all)030101 anatomy & morphologybusinessJournal of Clinical and Experimental Dentistry
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Dental status, salivary flow, and sociodemographic aspects in Sheehan Syndrome patients

2018

Background Sheehan’s syndrome (SS) is one of the leading causes of hypopituitarism in developing countries. It occurs after postpartum necrosis of the pituitary gland, and it is considered a significant public health problem. This paper, apparently unpublished, aimed to perform an analysis on oral aspects in patients with SS. Material and Methods A cross-sectional study was performed with 23 women diagnosed with SS at the Division of Endocrinology and Diabetes (Walter Cantídio University Hospital, Fortaleza, Brazil). Results Data on sociodemographic, dental and salivary flow aspects were collected through a clinical approach and a panoramic radiograph request. The mean age was 64 ± 11.5 yea…

0301 basic medicinePediatricsmedicine.medical_specialtyPanoramic radiographMaxillary sinus030209 endocrinology & metabolismHypopituitarismXerostomiaHypopituitarismTooth Loss03 medical and health sciences0302 clinical medicineDiabetes mellitusHumansMedicineGeneral DentistryAgedOral Medicine and Pathologybusiness.industryResearchPublic healthMiddle Aged:CIENCIAS MÉDICAS [UNESCO]University hospitalmedicine.diseaseSheehan SyndromeCross-Sectional Studiesmedicine.anatomical_structureSocioeconomic FactorsOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASHipopituitarismoFemaleSurgery030101 anatomy & morphologybusinessOral medicineBrazilMedicina Oral Patología Oral y Cirugia Bucal
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Development of an RNA-based kit for easy generation of TCR-engineered lymphocytes to control T-cell assay performance.

2018

Cell-based assays to monitor antigen-specific T-cell responses are characterized by their high complexity and should be conducted under controlled conditions to lower multiple possible sources of assay variation. However, the lack of standard reagents makes it difficult to directly compare results generated in one lab over time and across institutions. Therefore TCR-engineered reference samples (TERS) that contain a defined number of antigen-specific T cells and continuously deliver stable results are urgently needed. We successfully established a simple and robust TERS technology that constitutes a useful tool to overcome this issue for commonly used T-cell immuno-assays. To enable users t…

0301 basic medicineRNA StabilityComputer scienceT cellPerformanceCancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2]RNA StabilityT-LymphocytesImmunologyCell Culture TechniquesComputational biology03 medical and health sciences0302 clinical medicineAll institutes and research themes of the Radboud University Medical CenterHigh complexityValidationHLA-A2 AntigenmedicineImmunology and AllergyHumansImrnunoguidingRNA MessengerCell EngineeringT-cell assaysReceptors Chimeric AntigenImmunomagnetic SeparationElectroporationT-cell receptorRNAReference StandardsStandardizationImmunomonitoring030104 developmental biologymedicine.anatomical_structureElectroporationBlood Buffy CoatFeasibility StudiesBiological Assay030215 immunologyJournal of immunological methods
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Usherin defects lead to early-onset retinal dysfunction in zebrafish

2018

Mutations in USH2A are the most frequent cause of Usher syndrome and autosomal recessive nonsyndromic retinitis pigmentosa. To unravel the pathogenic mechanisms underlying USH2A-associated retinal degeneration and to evaluate future therapeutic strategies that could potentially halt the progression of this devastating disorder, an animal model is needed. The available Ush2a knock-out mouse model does not mimic the human phenotype, because it presents with only a mild and late-onset retinal degeneration. Using CRISPR/Cas9-technology, we introduced protein-truncating germline lesions into the zebrafish ush2a gene (ush2a(rmc1): c.2337_2342delinsAC; p.Cys780GlnfsTer32 and ush2a(b1245): c.15520_…

0301 basic medicineRetinal degenerationGenotyping TechniquesUsher syndrome2804 Cellular and Molecular NeuroscienceApoptosis030105 genetics & heredityBiologyArticleRetinaGermlineSensory disorders Donders Center for Medical Neuroscience [Radboudumc 12]Gene Knockout Techniques03 medical and health sciencesCellular and Molecular NeuroscienceUSH2 complex2809 Sensory SystemsAll institutes and research themes of the Radboud University Medical CenterRetinitis pigmentosaElectroretinographymedicineotorhinolaryngologic diseasesJournal ArticleAnimalsMicroscopy ImmunoelectronZebrafishZebrafishExtracellular Matrix ProteinsRetinal DegenerationMembrane ProteinsZebrafish ProteinsRetinal Photoreceptor Cell Outer Segmentmedicine.diseasebiology.organism_classification2731 OphthalmologySensory Systems10124 Institute of Molecular Life SciencesCell biologyDisease Models AnimalOphthalmology030104 developmental biologyGene Expression RegulationEctodomainMutation570 Life sciences; biologyXenotropic and Polytropic Retrovirus ReceptorUsher SyndromesErg
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Adherence to recommended intake of pulses and related factors in university students in the UniHcos project

2020

This study was supported by the National Drug Plan, Ministry of Health, Social Services and Equality of Spain (Grants: 2010|145 and 2013|034).

0301 basic medicineSociodemographic FactorsUniversitiesMedicine (miscellaneous)Social WelfareNutrition Policy03 medical and health sciences0302 clinical medicineEnvironmental healthMedicineHumans030212 general & internal medicineProspective StudiesStudentsPulsesNutritionRelated factors030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryFeeding BehaviorLegumesDietUniversity studentsCross-Sectional StudiesDiet qualitySpainMedicina Preventiva y Salud PúblicaChristian ministrybusinessEdible GrainDiet qualityRecommended Intake
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Global surveillance of trends in cancer survival 2000-14 (concord-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18…

2018

Eser, Sultan (Balikesir Author)

0301 basic medicineUniversal Health Coveragepopulation-based registriesRelative SurvivalSettore MED/42 - Igiene Generale E ApplicataCancer -- TreatmentHumans; Neoplasms; Population Surveillance; Registries; Survival Rate; Medicine (all)0302 clinical medicineNeoplasmsRegistriescancer survivaleducation.field_of_studyRelative survivalMedicine (all)EPICENEGeneral Medicine3. Good healthSurvival Ratetrend030220 oncology & carcinogenesisPopulation SurveillancePublic-Healthcancer surveillanceLiver cancersurvival ; cancer registry ; CONCORD-3CureChildhood-Cancermedicine.medical_specialtypopulation-based cancer registriesWomens CancersPopulationMedicine (all)cancer survival population-based cancer registriesSocio-culturaleUnited-StatessurvivalArticle03 medical and health sciencesBreast cancerCancer epidemiologymedicineHumansNordic-CountriesCancer -- MortalityeducationSurvival rateCancer preventionAlternative Approachbusiness.industryPublic healthCancerCancer -- Patients -- Long-term caremedicine.disease030104 developmental biologyHigh-Income Countries[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusinessDemography
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Evaluation of scientific output in Dentistry in Spanish Universities

2016

Background: The aim of this study was to assess the scientific output of Spanish universities that offer a bachelor’s degree in dentistry through the use of various bibliometric indicators. Material and Methods: A total of 21 universities offered a bachelor’s degree in dentistry in academic year 2016- 2017. The search for papers published by authors associated with these institutions was carried out using the selection of journals listed in the Journal Citation Reports (JCR) and the Web of Knowledge database for the period 1986-2017. On the basis of these data, we determined the output, the h-, g- and hg-indexes, the most productive authors, international collaborations, and the most releva…

0301 basic medicineUniversitiesOral surgerymedia_common.quotation_subjectLibrary scienceDentistryUniversitatsBachelorOdontologia03 medical and health sciencesInvestigació0302 clinical medicineCitation rateMedicineImpact factorGeneral Dentistrymedia_commonRecercaPublishingUniversityAcademic yearImpact factorbusiness.industryResearch:CIENCIAS MÉDICAS [UNESCO]030104 developmental biologyOtorhinolaryngologyKnowledge baseSpain030220 oncology & carcinogenesisDentistryUNESCO::CIENCIAS MÉDICASSurgeryJournal Impact FactorOral SurgerybusinessCitationH-indexOral medicine
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CO2 flux emissions from the Earth's most actively degassing volcanoes, 2005-2015

2019

AbstractThe global carbon dioxide (CO2) flux from subaerial volcanoes remains poorly quantified, limiting our understanding of the deep carbon cycle during geologic time and in modern Earth. Past attempts to extrapolate the global volcanic CO2 flux have been biased by observations being available for a relatively small number of accessible volcanoes. Here, we propose that the strong, but yet unmeasured, CO2 emissions from several remote degassing volcanoes worldwide can be predicted using regional/global relationships between the CO2/ST ratio of volcanic gases and whole-rock trace element compositions (e.g., Ba/La). From these globally linked gas/rock compositions, we predict the CO2/ST gas…

0301 basic medicineVolcanologylcsh:MedicineAtmospheric sciencesCarbon cycleVolcanic Gases03 medical and health scienceschemistry.chemical_compound0302 clinical medicine[SDU.STU.VO]Sciences of the Universe [physics]/Earth Sciences/Volcanologyeventlcsh:Scienceevent.disaster_typeCarbon dioxide in Earth's atmospheregeographyMultidisciplinarygeography.geographical_feature_categoryAtmospheric carbon dioxidelcsh:RTrace elementFOS: Earth and related environmental sciencesVolcanologyGeochemistry030104 developmental biologyVolcanochemistry[SDU]Sciences of the Universe [physics]Carbon dioxideSubaerialEnvironmental scienceVolcanoeslcsh:Q030217 neurology & neurosurgeryvolcanic gas fluxes voclanoes
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