Search results for "Urea"

showing 10 items of 888 documents

Emerging Tiger? The Paradoxes of the Philippine Economy

2017

The Republic of the Philippines is an exception in the East and Southeast Asia realm. One of the richest countries of the region at the end of World War II, its rankings have slipped, and its growth rates have been weak for several decades. We examine the main causes of the mediocre economic performance of the country since the 1950s. Many analysts have pointed out an excessive bureaucracy, high levels of corruption and the lack of industrial investment in a country dominated by landed interests. After the high debt incurred during the Marcos administration, Philippine leaders have made every effort to improve the debt situation, choosing to pay back loans, but under investing in infrastruc…

PovertyInformal sectorbusiness.industryCorruptionmedia_common.quotation_subjectGlobalizationGeographyEconomyDebtSecondary sector of the economyDevelopment economicsBureaucracybusinessTertiary sector of the economymedia_common
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THE INTEGRATION OF GREEN-BUILDING TASKS AND PROJECT-DESIGN PROCESSO - CASE STUDY

2018

The development of a green-building project following a specific reference standard such as LEED, brings new conditions and restrains for all subjects involved in the process. Such changes affect technicians, owners, bureaucracy and also the management tasks either during design or construction phases.  Within this scope, the management of sustainabilityrelated activities plays a key role for the optimization of the design-project development. This research analyzes the design process of two different case-study projects undergoing the same green-building certification from the project management perspective. In both project sustainability-related activities were performed throughout the de…

Process managementProcess (engineering)Computer sciencemedia_common.quotation_subjectCertificationNA1-9428green-buildingintegrated processLEEDArchitectureLEANProject managementmedia_commonScope (project management)business.industryleedprocess wasteGreen-buildingSchedule (project management)Ciências Sociais Aplicadas (Arquitetura e UrbanismoleanEngineering (General). Civil engineering (General)project managementSustainabilityBureaucracyDesign)TA1-2040businessEngineering design processMix Sustentável
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Laura Thermes. Progetti per il Sud. L'area Metropolitana dello Stretto

2014

Progetti per il sud. Tesi di laurea

Progetti per il sud. Tesi di laureaSettore ICAR/14 - Composizione Architettonica E UrbanaSettore ICAR/16 - Architettura Degli Interni E Allestimento
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Cytotoxicity of 40 Egyptian plant extracts targeting mechanisms of drug-resistant cancer cells

2019

Abstract Background The multidrug resistance (MDR) phenotype encounters a major challenge to the success of established chemotherapy in cancer patients. We hypothesized that cytotoxic medicinal plants with novel phytochemicals can overcome MDR and kill MDR-cells with similar efficacy as drug sensitive cells. Purpose We evaluated plant extracts from an unexplored ecosystem in Egypt with unusual climate and nutrient conditions for their activity against sensitive and multidrug-resistant cancer cell lines. Material and methods/study design Methylene chloride: methanol (1:1) and methanol: H2O (7:3) extracts of 40 plants were prepared resulting in a sum of 76 fraction containing compounds with v…

Programmed cell deathCell SurvivalPhytochemicalsPharmaceutical ScienceApoptosisCentaureaWithaniaPulicariaMagnoliopsida03 medical and health sciences0302 clinical medicineCell Line TumorNeoplasmsDrug DiscoveryHumansCytotoxic T cellViability assayCytotoxicity030304 developmental biologyMembrane Potential MitochondrialPharmacology0303 health sciencesPlants MedicinalbiologyPlant ExtractsChemistryWithaniabiology.organism_classificationAntineoplastic Agents PhytogenicMolecular biologyDrug Resistance MultipleMultiple drug resistanceComplementary and alternative medicineDrug Resistance NeoplasmCell culture030220 oncology & carcinogenesisCancer cellMolecular MedicineEgyptReactive Oxygen SpeciesPhytotherapyPhytomedicine
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Analysis of serine proteases from marine sponges by 2-D zymography.

2007

Proteolytic activities isolated from the marine demosponges Geodia cydonium and Suberites domuncula were analyzed by 2-D zymography, a technique that combines IEF and zymography. After purification, a 200 kDa proteolytically active protein band was obtained from G. cydonium when analyzed in gelatin copolymerized 1-D zymograms. The enzymatic activity was quantified using alpha-N-benzoyl-D-arginine p-nitroanilide (BAPNA) as a substrate and corresponded to a serine protease. The protease activity was resistant to urea and SDS. DTT and 2-mercaptoethanol (2-ME) did not significantly change the protease activity, but induced a shift in molecular mass of the proteolytic band to lower M(r) values a…

Proteasesmedicine.medical_treatmentClinical BiochemistryBiologyBenzoylarginine NitroanilideBiochemistryAnalytical ChemistrySubstrate SpecificitySerinemedicineAnimalsUreaZymographyElectrophoresis Gel Two-DimensionalMercaptoethanolSerine proteasechemistry.chemical_classificationProteaseMolecular massSerine EndopeptidasesSodium Dodecyl Sulfatebiology.organism_classificationMolecular biologyPoriferaSuberites domunculaEnzyme ActivationMolecular WeightDithiothreitolEnzymeBiochemistrychemistrybiology.proteinElectrophoresis
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Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex.

2002

Folding and post-translational modification of the thyroid hormone precursor, thyroglobulin (Tg), in the endoplasmic reticulum (ER) of the thyroid epithelial cells is facilitated by several molecular chaperones and folding enzymes, such as BiP, GRP94, calnexin, protein disulfide isomerase, ERp72, and others. They have been shown to associate simultaneously and/or sequentially with Tg in the course of its maturation, thus forming large heterocomplexes in the ER of thyrocytes. Here we present evidence that such complexes include a novel member, an ER-resident lumenal protein, ERp29, which is present in all mammalian tissues with exceptionally high levels of expression in the secretory cells. …

Protein DenaturationProtein FoldingImmunoprecipitationmedicine.medical_treatmentBlotting WesternThyroid GlandThyrotropinBiologyEndoplasmic ReticulumLigandsBiochemistryThyroglobulinRats Sprague-DawleyCalnexinmedicineCentrifugation Density GradientAnimalsUreaSecretionProtein disulfide-isomeraseMolecular BiologyCells CulturedHeat-Shock ProteinsThyroid Epithelial CellsChromatographyEndoplasmic reticulumCell BiologyPrecipitin TestsRatsCross-Linking ReagentsBiochemistryLiverMicroscopy FluorescenceMicrosomes LiverProtein foldingThyroglobulinProtein BindingThe Journal of biological chemistry
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Digital discretion: A systematic literature review of ICT and street-level discretion

2018

Public AdministrationSociology and Political ScienceE-GovernmentCommunicationmedia_common.quotation_subject05 social sciencesPublic administrationDiscretionStreet-level bureaucracy0506 political scienceSystematic reviewInformation and Communications Technology0502 economics and business050602 political science & public administrationSociology050203 business & managementInformation Systemsmedia_commonInformation Polity
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Amministrazione performante e sistema dei controlli interni

2023

Since the origins of post-unitary reform processes, analyses, and reconstructions aimed at deepening the needs and development paths for maximizing the functioning of the italian administration have directly or indirectly included the legal institutions of administrative control. Controls have progressively become an essential thematic axis in the characterization of the fundamental contents of the formation of the administrative state and the 'administrative question' of conformity in public organization and administrative activity to the principle of legality. They are seen as a specific legal institution, in which it is possible to interpret both the evolution of the state organization a…

Public administration good administration control function internal administrative controls inescapable duties of solidarity bureaucratic control to managerial control responsible StateSettore IUS/10 - Diritto Amministrativo
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Conformational and Tautomeric Control by Supramolecular Approach in Ureido-N-iso-propyl,N’-4-(3-pyridin-2-one)pyrimidine

2019

Ureido-N-iso-propyl,N&rsquo

PyrimidineStereochemistryMolecular ConformationSupramolecular chemistryPharmaceutical ScienceArticleCatalysisAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compoundIsomerismlcsh:Organic chemistryDrug DiscoveryPyridineUreaMoleculeMoietyPhysical and Theoretical ChemistryMolecular switchvetysidoksetintermolecular interactionsOrganic ChemistryTemperaturemolekyylithydrogen bondingTautomermolecular switchKineticstautomerismPyrimidineschemistryChemistry (miscellaneous)Proton NMRQuantum TheoryThermodynamicsMolecular MedicineProtonstautomeria
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Determination of five pesticide residues in oranges by matrix solid-phase dispersion and liquid chromatography to estimate daily intake of consumers.

2001

Abstract Residues of benzoylphenylurea insecticides (diflubenzuron, hexaflumuron, and flufenuxuron), carboxamide acaricides (hexythiazox), and carbamate insecticides (benfuracarb) were determined in 150 orange fruit samples from September 1998 to June 1999, to estimate exposure of the Valencian population to oranges contaminated with these newly developed pesticides. The method for monitoring these residues is based on matrix solid-phase dispersion and liquid chromatography with UV or atmospheric pressure chemical ionization/mass spectrometry (APCI/MS) detection. Orange samples representing 11 varieties were collected from an agricultural cooperative and examined for the 5 pesticides. In 74…

Quality ControlCarbamateCitrusInsecticidesBenzoylphenylureamedicine.medical_treatmentPopulationFood ContaminationOrange (colour)Mass SpectrometryAnalytical Chemistrychemistry.chemical_compoundmedicineEnvironmental ChemistryeducationBenzofuransPharmacologyeducation.field_of_studyChromatographyPesticide residueChemistryAcaricidePhenylurea CompoundsPesticide ResiduesReproducibility of ResultsPesticideDiflubenzuronBenzamidesbeta-AlanineDiflubenzuronAgronomy and Crop ScienceFood ScienceChromatography LiquidJournal of AOAC International
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