Search results for "Urinary bladder"

showing 10 items of 327 documents

Cigarette Smoking Status at Diagnosis and Recurrence in Intermediate-risk Nonemuscle-invasive Bladder Carcinoma

2013

Objective To study the effect of smoking status at diagnosis on recurrence in intermediate-risk non–muscle-invasive bladder carcinoma treated by transurethral resection (TUR) of the bladder and early intravesical chemotherapy. Methods Tumor characteristics and smoking status were recorded in 395 patients entered in a randomized multicenter trial comparing 2 different schedules of early intravesical chemotherapy. All patients received intravesical epirubicin (80 mg/50 mL) within 6 hours after TUR, followed by 5 more weekly instillations with (arm B) or without (arm A) monthly instillations for 1 year. Smoking habit was investigated at diagnosis through a structured questionnaire. Multivariat…

AdultMalemedicine.medical_specialtyMultivariate analysisTime Factorsintravesical chemotherapy non-muscle invasive bladder cancerUrologymedicine.medical_treatmentcigarette smokingKaplan-Meier EstimateCystectomyGastroenterologyDisease-Free SurvivalSettore MED/24 - UrologiaCystectomyCigarette smokingRisk FactorsMulticenter trialInternal medicinemedicineCarcinomaHumansAgedEpirubicinProportional Hazards ModelsAged 80 and overAntibiotics AntineoplasticProportional hazards modelbusiness.industryCarcinomaSmokingMiddle AgedFormer Smokermedicine.diseaseintermediate-risk tumorrecurrence.Combined Modality TherapySurgeryUrinary Bladder NeoplasmsMultivariate AnalysisFemaleNeoplasm Recurrence LocalbusinessEpirubicinmedicine.drug
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Ultrasonographical aspects of urinary schistosomiasis: Assessment of morphological lesions in the upper and lower urinary tract

1986

Ultrasonographic evaluation of 213 patients with urinary schistosomiasis in different age groups was performed in an endemic area of the Democratic Republic of Congo. The results were compared with 94 age matched controls without urinary schistosomiasis. In patients the bladder showed thickening of the wall, polypoid lesions of the mucosa and bladder wall, calcifications and urinary retention. Urinary tract obstruction, predominantly unilateral, was demonstrated. The lesions increased in severity with the intensity of infection, parallel to an increase in ova excretion. Children aged between 8 and 19 years were most severely affected. Pathological lesions of the upper urinary tract were rar…

AdultMalemedicine.medical_specialtyPathologyAdolescentUrinary systemUrinary BladderHelminthiasisSchistosomiasisKidneyGastroenterologySchistosomiasis haematobiaInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingChildPathologicalAgedUltrasonographyUpper urinary tractUrinary bladderUrinary retentionbusiness.industryInfantMiddle Agedmedicine.diseasemedicine.anatomical_structureChild PreschoolPediatrics Perinatology and Child HealthFemaleUretermedicine.symptomUrinary tract obstructionbusinessPediatric Radiology
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Are referral centers for non-muscle invasive bladder cancer compliant to EAU guidelines? A report from the vesical antiblastic therapy Italian study

2011

<i>Introduction:</i> Adherence to international guidelines is viewed as a prerequisite for optimal medical care delivery. Previously reported surveys for non-muscle-invasive bladder cancer (NMIBC) employed mailed questionnaires to urologists or patients resulting in conflicting degrees of agreement with existing guidelines. In the current study, contemporary information on the management of NMIBC was generated from a sample of Italian centers. <i>Patients and Methods:</i> Eight Italian referral centers for the treatment of NMIBC were asked to collect information relative to all consecutive patients with a histology-proven NMIBC undergoing a transurethral resection fr…

AdultMalemedicine.medical_specialtyReferralUrologyNon-muscle-invasive bladder cancereducationIntravesical therapyMedical careSettore MED/24 - Urologianon-muscle invasive bladder cancer; intravesical therapy; guidelines;non-muscle invasive bladder cancermedicineHumansNeoplasm InvasivenessEAU guidelinesguidelinesReferral and ConsultationAgedGynecologyAged 80 and overBladder cancerbusiness.industryGeneral surgeryBladder cancercompliant to EAU guidelinesMiddle Agedmedicine.diseaseBladder cancer; EAU guidelines; Intravesical therapy; Non-muscle-invasive bladder cancerItalyUrinary Bladder Neoplasmsnon-muscle-invasivePractice Guidelines as TopicFemaleGuideline AdherencebusinessNon muscle invasiveguideline
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Colonic Conduit in Children

1996

Complication rates of up to 86.6% have been reported after creation of an ileal conduit. In contrast to others, we construct an antirefluxing isoperistaltic colonic for incontinent diversion in children.Between 1968 and 1989 a colonic conduit was created in 105 patients up to age 20 years for neurogenic bladder (76), bladder exstrophy (16) and other reasons (13). Long-term followup (minimum 5 years, mean 16.3 years, range 5 to 26) was possible in 84 patients (159 renal units).Early and late stenosis at the ureterocolic anastomosis, and stomal stenosis occurred in 7.6 and 15.5% of the cases, respectively. Renal calculi developed in 8.2% of the renal units. Eight kidneys without function afte…

AdultMalemedicine.medical_specialtyTime FactorsAdolescentColonUrologyUrinary Diversionurologic and male genital diseasesStomal stenosisPostoperative ComplicationsRecurrent pyelonephritisHumansMedicineChildUpper urinary tractbusiness.industryUrinary Bladder DiseasesInfantColonic conduitUreterocolic anastomosismedicine.diseaseSurgeryBladder exstrophyStenosisChild PreschoolFemalebusinessComplicationFollow-Up StudiesThe Journal of Urology
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The fate of patients with locally advanced bladder cancer treated conservatively with neoadjuvant chemotherapy, extensive transurethral resection and…

1998

Purpose: We assess the results of bladder preservation for infiltrating bladder cancer. The potential for neoadjuvant chemotherapy followed by extensive transurethral resection and radiotherapy was evaluated in 40 patients with T2-T4a G2-G3 bladder carcinoma. Materials and Methods: From 1983 to 1995, 40 patients with bladder cancer underwent bladder sparing treatment, consisting of neoadjuvant chemotherapy, extensive transurethral resection and radiotherapy. Most patients had T3G3 cancer. A deep transurethral resection biopsy was performed before and after chemotherapy, and an extensive transurethral resection was repeated at the end of radiotherapy. Of the patients 30 received cisplatin an…

AdultMalemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentBladderUrologyTransitional cellSettore MED/24 - UrologiaCystectomyCarcinomaMedicineHumansAgedNeoplasm StagingAged 80 and overCarcinoma Transitional CellUrinary bladderBladder cancerRadiotherapybusiness.industryRemission InductionCarcinomaCancerMiddle Agedmedicine.diseaseVinblastineSurgeryRadiation therapyTransitional cell carcinomamedicine.anatomical_structureUrinary Bladder NeoplasmsChemotherapy AdjuvantFemaleDrug therapybusinessmedicine.drugFollow-Up Studies
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Evaluation of urodynamic studies by computer

1978

In an attempt to simplify urodynamic evaluation, the data obtained from cystometry, urethral profile and flowmetry were analysed using the ICS recommendations for standardization and terminology. All studies were compiled from check lists feasible for computation. The aim was to establish standards and "typical" changes for the normal bladder and pathological states to enable automatic readout of computed data. The results did, in fact, show "typical" changes but failed to establish standard measurements suitable for completely computed diagnoses.

AdultMalemedicine.medical_specialtyUrethral ObstructionAdolescentStandardizationManometryUrologyUrinary BladderUrodynamic studiesTerminologyUrethraHydrostatic PressuremedicineHumansMedical physicsDiagnosis Computer-AssistedUrinary Bladder NeurogenicMedical diagnosisChildAgedmedicine.diagnostic_testElectromyographybusiness.industryInfantCystometryMiddle AgedSurgeryUrinary IncontinenceChild PreschoolNormal bladderFemalebusinessUrological Research
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Long-term urinary dysfunction after mesorectal excision: a prospective study with intraoperative electrophysiological confirmation of nerve preservat…

2006

Bladder dysfunctions are well-recognized complications after nerve-sparing mesorectal excision for rectal cancer. This study sought to symptomatically analyze the extent of recovery from major and minor urinary symptoms in patients with signs of bladder denervation.Sixty-two patients with mesorectal excision for rectal cancer were investigated prospectively. Pelvic autonomic nerve preservation (PANP) was assessed macroscopically and with the aid of intraoperative electrical stimulation of pelvic autonomic nerves (INS). Bladder function was evaluated with the International Prostate Symptom Score (IPSS) and the Quality of life index (Qol). Median follow-up was 20 months (range 3-40 months).Fo…

AdultMalemedicine.medical_specialtyUrinary systemUrinary BladderElectric Stimulation Therapyurologic and male genital diseasesQuality of lifeParasympathetic Nervous SystemMonitoring IntraoperativemedicineHumansProspective StudiesProspective cohort studyNeurogenic bladder dysfunctionMesorectalAgedAged 80 and overbusiness.industryRectal NeoplasmsRectumGeneral MedicineMiddle AgedUrinary functionmedicine.diseaseSurgeryTreatment OutcomeUrinary IncontinenceOncologyQuality of LifeSurgeryInternational Prostate Symptom ScoreFemaleComplicationbusinessFollow-Up StudiesEuropean journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
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Does the Compliance to Intravesical BCG Differ between Common Clinical Practice and International Multicentric Trials?

2015

<b><i>Introduction:</i></b> The aim of this study was to analyze the reasons for intravesical BCG interruption in clinical practice. BCG for at least one year is advocated as the best regimen to treat high-risk non-muscle invasive bladder cancer (NMIBC). However, almost 50% of patients don't complete it. Toxicity accounts for 10% of dropouts in international trials. <b><i>Materials and Methods:</i></b> Patients with T1HG NMIBC undergoing 1-year BCG were enrolled in this study. BCG was administered for one year. Toxicity and causes of treatment interruption were recorded. <b><i>Results:</i></b> A total of 411 patients we…

AdultMalemedicine.medical_specialtyUrologyInternational CooperationAntineoplastic AgentsSettore MED/24 - UrologiaMedication AdherenceSocial lifeCohort StudiesRecurrenceInternal medicinemedicineHumansAgedBladder cancerbusiness.industryMiddle Agedmedicine.diseaseSurgeryClinical PracticeRegimenAdministration IntravesicalTreatment OutcomeUrinary Bladder NeoplasmsTreatment interruptionToxicityBCG VaccineDisease ProgressionIntravesical bcgPatient ComplianceFemalenon muscle invasive bladder cancer Bacillus Calmette Guèrin intravesical instillation immunotherapy compliance toxicityNeoplasm Recurrence LocalbusinessCohort studyUrologia internationalis
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The clinical use of statistical permutation test methodology: a tool for identifying predictive variables of outcome.

2015

<b><i>Objectives:</i></b> To identify the predictive variables affecting the outcome after radical surgery for bladder cancer by a newer statistical methodology, i.e. nonparametric combination (NPC). <b><i>Methods:</i></b> A multicenter study enrolled 1,312 patients who had undergone radical cystectomy for bladder cancer in 11 Italian oncological centers from January 1982 to December 2002. A statistical analysis<b> </b>of their medical history and diagnostic, pathological and postoperative variables was performed using a NPC test. The<b> </b>patients were included in a comprehensive database with medical history and cli…

AdultMalemedicine.medical_specialtyUrologyStatistics as TopicHydronephrosisnonparametric combinationCystectomyOutcome (game theory)Statistics NonparametricBladder cancer; Permutation test; PrognosisSettore MED/24 - UrologiaBladder cancer Prognosis Permutation testPredictive Value of TestsResamplingMedicineHumansPermutation testRadical surgeryIntensive care medicineAgedNeoplasm StagingRetrospective StudiesAged 80 and overCarcinoma Transitional CellBladder cancerbusiness.industryBladder cancerProstatePermutation testsMiddle Agedmedicine.diseasePrognosisradical surgery for bladder; nonparametric combinationradical surgery for bladderSurgeryPatient Outcome Assessmentbladder cancer; Prognosis; Permutation testsItalyUrinary Bladder NeoplasmsBladdder Cancer Cystectomy outcome statistical methodologyData Interpretation StatisticalLymphatic MetastasisMultivariate AnalysisFemalePredictive variablesradical surgery for bladder nonparametric combinationbusiness
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Teaching transurethral resection of the bladder: still a challenge?

2003

Abstract Objectives To report on our 2-year experience in teaching transurethral resection (TUR) of bladder tumors to five trainees. We analyzed their problems, as well as those of the teachers, and present our solutions. Methods Between April 2000 and March 2002, five residents and three members of the staff took part in a training program to teach TUR of the bladder. From a total of 692 patients with bladder tumors admitted for treatment to our department, 417 were selected for the study. These 417 had papillary tumors of small to medium size (maximum 25 mm in diameter). The mean patient age was 61 years (range 32 to 92) for men (n = 322; 77%) and 68.4 years (range 48 to 91) for women (n …

AdultMalemedicine.medical_specialtyUrologyUrinary BladdereducationPerforation (oil well)ResectionPostoperative ComplicationsPatient ageHumansMedicineProspective StudiesAgedAged 80 and overUrinary bladderSurgical approachbusiness.industryInternship and ResidencyMiddle AgedCarcinoma PapillarySurgerymedicine.anatomical_structureUrethraUrinary Bladder NeoplasmsGeneral SurgeryUrologic Surgical ProceduresEducation Medical ContinuingFemalebusinessTraining programComplicationProgram EvaluationUrology
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