Search results for "Urination"

showing 10 items of 32 documents

The molecular characterization of a depurinated trial DNA sample can be a model to understand the reliability of the results in forensic genetics

2014

The role of DNA damage in PCR processivity/fidelity is a relevant topic in molecular investigation of aged/forensic samples. In order to reproduce one of the most common lesions occurring in postmortem tissues, a new protocol based on aqueous hydrolysis of the DNA was developed in vitro. Twenty-five forensic laboratories were then provided with 3.0 μg of a trial sample (TS) exhibiting, in mean, the loss of 1 base of 20, and a molecular weight below 300 bp. Each participating laboratory could freely choose any combination of methods, leading to the quantification and to the definition of the STR profile of the TS, through the documentation of each step of the analytical approaches selected. …

DNA depurination; Forensic genetics; PCR fidelity; STR typing; Biochemistry; Clinical BiochemistryPCR fidelityGenotyping TechniquesDNA damageSample (material)Clinical BiochemistryDNA depurinationReproducibility of ResultForensic geneticsBiologyPolymerase Chain ReactionBiochemistryNOAnalytical Chemistrylaw.inventionDNA depurination; PCR fidelity; STR typing; forensic genetics.Settore MED/43 - Medicina LegalelawSettore BIO/13 - Biologia ApplicataGenotypeHumansSTR typingGenotyping TechniquesPolymerase chain reactionProtocol (science)GeneticsMedicine (all)Reproducibility of ResultsForensic geneticDNAAmpliconDNA FingerprintingDNA depurination; Forensic genetics; PCR fidelity; STR typingSettore BIO/18 - GeneticaDNA depurination Forensic genetics PCR fidelity STR typingDNA profilingSettore MED/03 - Genetica MedicaMicrosatellite RepeatGenotyping TechniqueDNA depurination; Forensic genetics; PCR fidelity; STR typing;Microsatellite RepeatsHuman
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Late results of bladder stimulation in 11 patients: followup to 4 years.

1978

Abstract Direct stimulation of the detrusor muscle offers the best possibility to evacuate the bladder in highly selected patients. During the last 4 years 11 patients have undergone implantation of a bladder pacemaker. Followup revealed that 1 patient could void only during stimulation, while 7 patients had reflex evacuation and 3 had no function at all. An exceptional case report is presented.

Detrusor muscleAdultMalemedicine.medical_specialtyTime Factorsbusiness.industryUrologyUrinary BladderStimulationElectric Stimulation TherapyMiddle Agedurologic and male genital diseasesUrination DisordersLate resultsfemale genital diseases and pregnancy complicationsSurgerymedicine.anatomical_structureReflexMedicineHumansFemalebusinessDirect stimulationFollow-Up StudiesThe Journal of urology
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Laparoscopic endopelvic sacral implantation of a Brindley controller for recovery of bladder function in a paralyzed patient

2008

Background: A number of techniques are being investigated to accomplish bladder control recovery in paralyzed patients using the neurostimulation, but currently, all techniques are based on the dorsal implantation of the electrodes using a laminectomy. Methods: On 27 April 2006 we performed a laparoscopic implantation of a Finetech-Brindley bladder controller on the endopelvic sacral roots in a Th8 completely paralyzed woman who had previously undergone the removal of a Brindley controller due to an arachnoiditis after extrathecal implantation with intradural sacral deafferentation. Results: We required about 3.5 h for the entire surgical procedure; no complications occurred and the patient…

Finetech-Brindley bladder; LION technique; Spinal cord injuryNeurosurgical Procedureurologic and male genital diseasesNeurosurgical ProceduresLION techniqueLaparoscopyDefecationSpinal cord injurymedia_commonSpinal Cord InjurieUrinary bladdermedicine.diagnostic_testGeneral MedicineMiddle Agedmusculoskeletal systemfemale genital diseases and pregnancy complicationsElectrodes Implantedmedicine.anatomical_structureTreatment OutcomeNeurologyPatient SatisfactionAnesthesiaFemaleParaplegiaSpinal Nerve RootsHumanmusculoskeletal diseasesmedicine.medical_specialtySacrumPelvimedia_common.quotation_subjectUrinary BladderUrinationElectric Stimulation TherapySpinal cord injuryUrinationPelvisSpinal Nerve RootmedicineRetroperitoneal spaceHumansRetroperitoneal SpaceUrinary Bladder NeurogenicPelvisSpinal Cord InjuriesParaplegiabusiness.industrymedicine.diseaseSacrumSurgerybody regionsFinetech-Brindley bladderLaparoscopyNeurology (clinical)business
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Defining female voiding dysfunction: ICI-RS 2011

2012

Whilst symptoms of bladder outlet obstruction (BOO) and post micturition symptoms are more commonly reported in men a significant number of women may also complain of voiding dysfunction. However, despite the recent advances in the standardisation of terminology of lower urinary tract dysfunction there remains a lack of consensus regarding a precise diagnosis and definition of voiding abnormalities in women. In addition voiding symptoms may co-exist with storage symptoms as well as those associated with urinary incontinence. Consequently many patients present with a spectrum of different urinary symptoms, related to both storage and voiding, which may be multifactorial in origin or be relat…

Gynecologymedicine.medical_specialtyUrinary symptomsbusiness.industryUrologyUrinary systemmedia_common.quotation_subjectUrinary incontinenceurologic and male genital diseasesUrinationBladder outlet obstructionPredictive value of testsSeverity of illnessmedicineEtiologyNeurology (clinical)medicine.symptomIntensive care medicinebusinessmedia_commonNeurourology and Urodynamics
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Flexible-dose fesoterodine in elderly adults with overactive bladder: results of the randomized, double-blind, placebo-controlled study of fesoterodi…

2013

Objectives: To assess the efficacy and safety of flexible-dose fesoterodine in elderly adults with overactive bladder (OAB). Design: Twelve-week, randomized, double-blind, placebo-controlled trial. Setting: Sixty-one outpatient clinics in Europe, Israel, and Turkey. Participants: Seven hundred ninety-four individuals aged 65 and older (47% male) with OAB symptoms for 3 months or longer, mean of eight or more micturitions and three or more urgency episodes per 24 hours, at least some moderate problems on Patient Perception of Bladder Condition (PPBC), and Mini-Mental State Examination (MMSE) score of 20 or greater. Interventions: Participants were randomized to fesoterodine or placebo for 12…

MaleAgingmedicine.medical_specialtyEveningPlacebo-controlled studyUrinationUrinary incontinencePlaceboDrug Administration Schedulelaw.inventionDouble-Blind MethodRandomized controlled triallawSurveys and QuestionnairesmedicineFesoterodineHumansOutpatient clinicBenzhydryl CompoundsAgedRetrospective StudiesDose-Response Relationship DrugUrinary Bladder Overactivebusiness.industrymedicine.diseaseTreatment OutcomeOveractive bladderPhysical therapyFemaleGeriatrics and Gerontologymedicine.symptombusinessFollow-Up Studiesmedicine.drug
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Silicone-Silver Penile Prosthesis: Description, Operative Approach and Results

1980

A silicone penile prosthesis in which silver wires are embedded to allow for voluntary bending of the penis for urination and resting position and for straightening for intercourse is described. The implantation is done via a hemicircular incision on the dorsum of the penis in the sulcus coronarius. Buck's fascia is identified and opened, and the corpora are dilated up to 30F. After the exact length is determined with a special sizer the prosthesis is slipped into each corpus cavernosum. The advantage of this approach is the optimal insertion of the prosthesis distal to the sulcus coronarius, thereby preventing kinking of the glans during intercourse. Our experiences with the implantation i…

MaleDorsummedicine.medical_specialtySilverUrologymedia_common.quotation_subjectmedicine.medical_treatmentProsthesis DesignUrinationProsthesischemistry.chemical_compoundPostoperative ComplicationsSiliconeHumansMedicineGlansmedia_commonbusiness.industryPenile prosthesisProstheses and ImplantsFasciaSurgerymedicine.anatomical_structurechemistrySilicone ElastomersbusinessPenisPenisJournal of Urology
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SARS-CoV-2 infection associated with micturition syncope: Our experience with 4 case reports.

2020

Abstract Rationale: Syncope is described as the loss of consciousness and postural muscle tone with a short duration and fast onset. Micturition syncope can be caused by abnormal vasovagal response or by the dysfunction of the blood pressure regulating mechanism, which occurs before, during, or immediately after urination. Patient concerns: We present 4 cases of COVID-19 hospitalized in the Department of Infectious Diseases of the Academic Emergency Hospital Sibiu, Romania, cases that presented micturition syncope. Diagnoses: During hospitalization, patients confirmed with SARS-Cov-2 infection using real time reverse transcriptase-polymerase chain reaction (RT-PCR) assay, presented micturit…

MalePediatricsmedicine.medical_specialtymedia_common.quotation_subjectPneumonia ViralMicturition syncopeUrinationSyncope03 medical and health sciencesMuscle toneBetacoronavirus0302 clinical medicinemedicineAdrenal insufficiencyHumanscase report030212 general & internal medicineClinical Case Reportmicturition syncopePandemicsmedia_commonAgedbiologybusiness.industryRomaniaSARS-CoV-24900Syncope (genus)COVID-19General MedicineMiddle Agedmedicine.diseasebiology.organism_classificationPulmonary hypertensionPneumoniaBlood pressuremedicine.anatomical_structure030220 oncology & carcinogenesisFemalebusinessCoronavirus InfectionsResearch ArticleMedicine
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The effects of transdermal rotigotine on non-motor symptoms of Parkinson's disease: a multicentre, observational, retrospective, post-marketing study

2017

This study evaluated the effect of ≥6 months of transdermal rotigotine on non-motor and motor symptoms of patients with advanced Parkinson's disease.The study was conducted in Spain between September 2011 and December 2012 (ClinicalTrials.gov: NCT01504529). The primary efficacy variable was the change from baseline in non-motor symptoms, as assessed by changes in Parkinson's Disease Non-Motor Symptoms Questionnaire total scores at 6 months. Secondary endpoints included the assessment of motor symptoms by Unified Parkinson's Disease Rating Scale III scores.Data from 378 patients (mean age: 70.2 years; 56.9% male) with Parkinson's disease receiving rotigotine from were collected. Mean disease…

MaleSleep Wake Disordersmedicine.medical_specialtyParkinson's diseaseTetrahydronaphthalenesThiophenesDiseaseAdministration CutaneousMotor symptoms03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesProduct Surveillance PostmarketingmedicineHumans030212 general & internal medicineAgedRetrospective StudiesTransdermalAged 80 and overbusiness.industryGeneral NeuroscienceParkinson DiseaseRotigotineGeneral MedicineUrination Disordersmedicine.diseaseClinical PracticeTreatment OutcomeSpainDopamine AgonistsPhysical therapyNon motorFemaleObservational studyCognition Disordersbusiness030217 neurology & neurosurgerymedicine.drugInternational Journal of Neuroscience
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Enuresis Subtypes Based on Nocturnal Hypercalciuria: A Multicenter Study

2003

Purpose: Desmopressin may not be effective for nocturnal enuresis associated with polyuria and hypercalciuria. Nighttime hypercalciuria in an enuretic population from 5 centers and its correlation with nighttime polyuria were verified. Materials and Methods: A total of 450 enuretic patients (278 males, 172 females, mean age 9.7 years) were evaluated with 72-hour micturition charts, urinalysis, serum creatinine and osmolarity, diurnal and nocturnal electrolytes with fractional Na+ and K+ urinary excretion, and nocturnal (4 a.m.) plasma vasopressin. Creatinine electrolytes and osmolarity were measured in daytime (8 a.m. to 8 p.m.) and nighttime (8 p.m. to 8 a.m.) urine volumes. Patients were …

Malemedicine.medical_specialtyAdolescentendocrine system diseasesUrinalysisVasopressinsUrologymedia_common.quotation_subjectPopulationUrinary incontinenceUrologyUrinary incontinenceurologic and male genital diseasesUrinationDiagnosis DifferentialElectrolytesAdrenocorticotropic HormonePolyuriaEnuresisElectrolyteInternal medicineEnuresimedicineHumansEnuresis; Polyuria; Urinary incontinence; Vasopressin; Adolescent; Adrenocorticotropic Hormone; Calcium; Child; Circadian Rhythm; Creatinine; Deamino Arginine Vasopressin; Diagnosis Differential; Electrolytes; Enuresis; Female; Humans; Male; Polyuria; Vasopressins; UrologyDeamino Arginine VasopressinHypercalciuriaChildDesmopressineducationmedia_commoneducation.field_of_studymedicine.diagnostic_testPolyuriabusiness.industryEnuresismedicine.diseasefemale genital diseases and pregnancy complicationsCircadian RhythmEndocrinologyCreatinineCalciumFemalemedicine.symptombusinessVasopressinhormones hormone substitutes and hormone antagonistsHumanmedicine.drugJournal of Urology
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Predictive variables of spontaneous micturition recovery after acute urinary retention in men with benign prostatic enlargement: An observational pro…

2017

Objective: Acute urinary retention (AUR) is the sudden and painful inability to urinate spontaneously. AUR is one of the most significant complications of benign prostatic enlargement. The management of AUR is based on transurethral catheterization. Subsequent therapy is uncertain, but AUR seems to benefit from the use of alpha-blockers. The aim of this study was to evaluate the variables that could predict which patients would recover spontaneous micturition after trial without catheter. Methods: The present prospective observational study included men with AUR in an Italian tertiary care institute in 2016. Patients were catheterized and treated orally with fluoroquinolones, alpha-blockers…

Malemedicine.medical_specialtyNeurologymedia_common.quotation_subjectUrology030232 urology & nephrologyUrologyProstatic HyperplasiaUrinationUrinationSeverity of Illness IndexC-reactive protein03 medical and health sciences0302 clinical medicineProstatemedicineHumansProspective Studiesacute urinary retentionProspective cohort studymedia_commonAgedspontaneous micturition recoveryInternational Prostate Symptom ScorebiologyUrinary retentionbusiness.industryC-reactive proteinArea under the curveProstateOrgan SizeRecovery of FunctionMiddle AgedUrinary Retentionmedicine.anatomical_structureROC CurveNeurology030220 oncology & carcinogenesisArea Under CurveAcute Diseasebiology.proteinInternational Prostate Symptom Scoremedicine.symptombusinessUrinary Catheterization
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