Search results for "Uso"

Pauson–Khand reaction of fluorinated compounds

2020

The Pauson–Khand reaction (PKR) is one of the key methods for the construction of cyclopentenone derivatives, which can in turn undergo diverse chemical transformations to yield more complex biologically active molecules. Despite the increasing availability of fluorinated building blocks and methodologies to incorporate fluorine in compounds with biological interest, there have been few significant advances focused on the fluoro-Pauson–Khand reaction, both in the inter- and intramolecular versions. Furthermore, the use of vinyl fluorides as olefinic counterparts had been completely overlooked. In this review, we collect the advances both on the stoichiometric and catalytic intermolecular an…

Asialofetuin Liposomes for Receptor-Mediated Gene Transfer into Hepatic Cells

2003

Publisher Summary The liver is an excellent organ for gene transfer in treating a wide variety of diseases that affect liver function. It is an ideal organ for a high amount of expression of therapeutic genes and efficient systemic distribution of the resulting therapeutic proteins secreted into the bloodstream. For strategies of liver-destined gene therapy, the liver sinusoid endothelium contains pores with a mean diameter of 100 nm, which allow small vectors to leave the blood circulation and reach the hepatocytes. The preparation of asialofetuin–liposomes targeted to hepatocytes can be made by covalent coupling of asialofetuin glycoprotein (ASF) onto the liposome surface, by the use of h…

Dynamic evolution of the oscillatory Belousov-Zhabotinsky reaction upon addition of a non-ionic polymer

2006

Abstract The dynamic evolution of the oscillatory Belousov–Zhabotinsky reaction upon addition of increasing amount of the non-ionic polymer polypropylene glycol with molecular weight 425 g mol−1 (PPG-425) was investigated in a stirred-batch reactor by monitoring the Ce(IV) absorbance changes. The oscillatory parameters are significantly altered by the presence of the polymer. The findings obtained in the present work revealed that the PPG-425 is not only more effective, than other polymer previously [R. Lombardo, C. Sbriziolo, M.L. Turco Liveri, K. Pelle, M. Wittmann, Z. Noszticzius, in: J.A. Pojman, Q. Tran-Cong-Miyata (Eds.), Nonlinear Dynamics in Polymeric Systems, American Chemical Soci…

Effects of non-ionic micelles on transient chaos in an unstirred Belousov-Zhabotinsky reaction.

2001

The behaviour of the Ce(IV)-catalyzed Belousov-Zhabotinsky (BZ) system has been monitored at 20.0 degrees C in unstirred batch conditions in the absence and presence of different amounts of the non-ionic micelle-forming surfactants hexaethylene glycol monodecyl ether (C10E6) and hexaethylene glycol monotetradecyl ether (C14E6). The influence of the non-ionic surfactants on both the kinetics of the oxidation of malonic acid (MA) by Ce(IV) species and the behaviour of the BZ reaction in stirred batch conditions has also been studied over a wide surfactant concentration range. The experimental results have shown that, in unstirred batch conditions, at surfactant concentrations below the critic…

Inside Cover: Synthesis and Application of β-Substituted Pauson-Khand Adducts: Trifluoromethyl as a Removable Steering Group (Angew. Chem. Int. Ed. 2…

2013

E-Ring extended estrone derivatives: introduction of 2-phenylcyclopentenone to the estrone D-ring via an intermolecular Pauson–Khand reaction

2006

Abstract An expedient synthetic route to E-ring extended estrone derivatives is reported. Estrone-derived cyclopentenones were accessed by an intermolecular Pauson–Khand (PK) cycloaddition. It was found that electron donating and withdrawing substituents in the arylalkyne increased and decreased the yields of PK products, respectively. The stereochemistry of the products was elucidated by X-ray and NMR studies.

L'IMMAGINE FILMICA NELLA FORMAZIONE: LE NARRAZIONI SULLA VIOLENZA ALL'INFANZIA

2011

Il presente contributo rivolge l’attenzione alle risonanze emotive, alla soggettività di chi affronta il tema della violenza all’infanzia. Lo studio si propone di esplorare i processi attraverso i quali i soggetti, posti all’interno di un gruppo impegnato in attività formativa, organizzano informazioni e costruiscono rappresentazioni sull’abuso sui minori. Il gruppo dei partecipanti all’indagine è composto da 163 soggetti (122 studenti universitari, e 41 professionisti tra cui N = 12 agenti delle Forze dell’ordine e N = 29 operatori sociosanitari) ai quali è stata proposta la visione del film documentario Una storia americana (Capturing the Friedmans, USA 2003). I contenuti delle riflession…

Recognition and Civic Selection

2021

Large-scale immigration and the refugee crisis have caused many states to adapt ever stricter civic selection processes. This paper discusses the challenges arising from civic selection from the perspective of recognition theories. The argument is that recognition theories provide good conceptual tools with which to critically analyze civic selection and immigration. However, the paper also aims to highlight that many current institutional practices are problematic from the perspective of recognition. In the context of civic selection, it is helpful to understand recognition as something that comes in two analytically distinct modes: horizontal (or interpersonal) and vertical (or institutio…

The pedagogy of multiliteracies as a code breaker : A suggestion for a transversal approach to computing education in basic education

2021

While computing has been (re)introduced into the basic education curricula in various countries, its actual implementation appears to be inconsistent. There are schools in which computing education is commonplace, while the implementation seems to be lagging behind in others. There is emerging evidence that some teachers do not consider computing education relevant, meaningful and important and, thus, intentionally neglect its provision. This is problematic as understanding the principles of code and computing is crucial for agentic citizenship in the post-digital era. This paper argues that one main reason for these teachers' reluctance is the economy-driven discursive framing of computing…

Report WS1. Il binomio “Città porto”: conflitti e sinergie multilivello fra trasformazioni urbane e competitività globale

2012

The paper collects the best practices and considerations from two sessions of the workshop “Città porto: la dimensione multipla della pianificazione spaziale”. The leitmotiv of the first session’s reporters has been: the harbour, as urban gateway, origins conflicts, synergies and moments of cooperation with the urban structure. They’ve referred about North and South European harbours of medium level that, for advanced technical and logistic features and strategies of intervention, represent a substantial landmark for similar realities. Genoa, Rotterdam, Hamburg and Bilbao rehabilitation plans, despite their own peculiarities, have in fact dragged aspects of the industrial sector, urban desi…