Search results for "Uvea"

showing 10 items of 83 documents

Itinerario III. Una piccola capitale dell’Art Nouveau

2008

La ricchezza artistica da «piccola capitale dell’Art Nouveau» della Palermo Liberty è data non solamente dalle emergenze architettoniche più note ma anche dalle realizzazioni di opere “non firmate” (cosiddette minori), dalle arti in genere e dall’artigianato che, intesi nella loro perfetta fusione, contribuiscono a definire il concetto di “opera d’arte in tutto” sul quale si era concentrato il dibattito artistico architettonico internazionale. Affermatasi inizialmente come espressione dell’alta società più evoluta, votata ad una moderna celebrazione dei rituali della vita (con le preziose dimore che riverberavano nuovi modelli comportamentali, come il villino Florio di Basile) e della morte…

ITINERARIO ART NOUVEAU CAPITALE PALERMOSettore ICAR/18 - Storia Dell'Architettura
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The new social mouvements : the case of the Bulgarian green movement

2015

This study examines the Green Movement in Bulgaria (1987-2014) as a typical and specific example of the New Social Movements. It focuses on the interconnection between environmentalism, politics and participation. We present the movement along with its evolution and analyse it on three levels: macro (through its relation to the most important contemporary issues, phenomena and processes); meso (in the national context during the past three generations); and micro (through the prism of individuals and their experience). Our general approach is interdisciplinary, combining qualitative, comparative and quantitative methods. Bulgaria’s green movement is a citizen and political movement of a new…

IndividuNew CultureNouvelle cultureAuthentiqueNouvelle politiqueNew Social Movements[SHS.DROIT] Humanities and Social Sciences/LawEngagement citoyenCitizen EngagementIndividualDemocracyNouveaux mouvements sociauxDémocratieActeurNew PoliticsGreen MovementsBulgarieMouvements écologiquesActorBulgariaAuthentic
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Storia dell'Arte in Europa. Inghilterra

2014

Il saggio si offre come guida alla lettura dei maggiori fenomeni artistici fioriti in Inghilterra nel XIX secolo e affronta la genesi e lo sviluppo di tendenze e movimenti straordinari che si estendono dal Gothic Revival alle Arts and Crafts, dai Preraffaelliti all'Aesthetic Movement, dal Japonisme all'Art Nouveau. Il volume, ampiamente illustrato e corredato di bibliografia aggiornata, traccia un quadro storico-critico dell'età vittoriana senza tralasciare l'analisi delle maggiori opere d'arte dell'epoca, realizzata da artisti quali William Morris, Dante Gabriel Rossetti, Albert Moore, Lawrence Alma-Tadema, Aubrey Beardsley e molti altri autori, oggi al centro di un rinnovato interesse da …

JaponismeArts and CraftPreraffaellitiArti decorativeAesthetic MovementArt NouveauArte ingleseGothic RevivalArti figurative
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Le lyrisme ouvert de Jean-Michel Maulpoix: de Locturnes à Domaine public

2009

Estudio del lirismo en poemarios de Jean-Michel Maulpoix: desde Locturnes (1978) hasta Domaine public (1998).

Lirismo en la poesía francesa contemporánea. "Nouveau lyrisme".Poesía francesa de los siglos XX y XXIJean-Michel Maulpoix
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An anti-interleukin-2 receptor drug attenuates T- helper 1 lymphocytes-mediated inflammation in an acute model of endotoxin-induced uveitis.

2014

The aim of the present study was to evaluate the anti-inflammatory efficacy of Daclizumab, an anti-interleukin-2 receptor drug, in an experimental uveitis model upon a subcutaneous injection of lipopolysaccharide into Lewis rats, a valuable model for ocular acute inflammatory processes. The integrity of the blood-aqueous barrier was assessed 24 h after endotoxin-induced uveitis by evaluating two parameters: cell count and protein concentration in aqueous humors. The histopathology of all the ocular structures (cornea, lens, sclera, choroid, retina, uvea, and anterior and posterior chambers) was also considered. Enzyme-linked immunosorbent assays of the aqueous humor samples were performed t…

MaleChemokineAnatomy and PhysiologyDaclizumabmedicine.medical_treatmentlcsh:MedicineBiochemistryRedox SignalingOxidative DamageDaclizumabImmune PhysiologyMolecular Cell BiologyBasic Cancer ResearchSignaling in Cellular ProcessesInterferon gammalcsh:ScienceMultidisciplinarybiologyT CellsOxygen MetabolismCytokinemedicine.anatomical_structureOncologyAcute DiseaseCytokinesMedicineImmunotherapymedicine.symptomUveitismedicine.drugResearch ArticleSignal TransductionInterleukin 2Cell PhysiologyImmune CellsImmunologyInflammationAntibodies Monoclonal HumanizedSignaling PathwaysUveitisOcular SystemmedicineAnimalsBiologyInflammationbusiness.industrylcsh:RImmunityReceptors Interleukin-2UveaTh1 Cellsmedicine.diseaseeye diseasesEndotoxinsDisease Models AnimalMetabolismRats Inbred LewImmune SystemImmunoglobulin GImmunologybiology.proteinlcsh:Qsense organsMolecular NeurosciencebusinessNeurosciencePLoS ONE
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New-onset third-degree atrioventricular block because of autoimmune-induced myositis under treatment with anti-programmed cell death-1 (nivolumab) fo…

2017

There has been considerable progress in treating malignant melanoma over the last few years. The immune-checkpoint-inhibitors nivolumab and pembrolizumab have been approved by the Food and Drug Administration in 2014 for the therapy of metastatic melanoma. Anti-programmed cell death-1-blocking antibodies are known to cause immune-related adverse events. Physicians should be aware of common and rare side effects and pay attention to new ones. We therefore report a severe and life-threatening side effect of anti-programmed cell death-1 immunotherapy with nivolumab that has not been previously reported: the development of a third-degree atrioventricular block. After a second infusion with nivo…

MaleUveal NeoplasmsOncologyCancer Researchmedicine.medical_specialtyMyocarditisSide effectDermatologyPembrolizumab030204 cardiovascular system & hematologyAutoimmune Diseases03 medical and health sciencesAntineoplastic Agents ImmunologicalFatal Outcome0302 clinical medicineInternal medicineHumansMedicineAtrioventricular BlockMelanomaMyositisMyositisbusiness.industryThird-degree atrioventricular blockMelanomaAntibodies MonoclonalMiddle Agedmedicine.diseaseNivolumabOncology030220 oncology & carcinogenesisImmunologyNivolumabbusinessAtrioventricular blockMelanoma Research
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Chromatic-achromatic perimetry in four clinic cases: Glaucoma and diabetes

2015

Color perimetry has interesting clinical application for the diagnosis and detection of certain eye conditions, due to the variations that certain diseases can cause in chromatic thresholds, both in the red-green (RG) and the blue-yellow (BY) pathways.[1,2,3,4] The separate study of the visual function of both the chromatic and achromatic mechanisms could be more efficient in detecting sensitivity variations, and such variations would not be obscured by the intrusion of other mechanisms. Currently, the supply of conventional perimeters that are capable of performing a chromatic perimetry test is very limited and with reduced options regarding the possibility of choosing the physical charact…

Maleretinakoniohemangioblastomagenetic structuresComputer sciencemelanocytosisGlaucomaretinal vasoproliferative tumorEyeTwo stageslaw.inventionintra-arterial chemotherapyretinal capillary hemangiomaIntrusionlcsh:Ophthalmologylawperiocular chemotherapyintravitreal chemotherapytreatmentdiabetesenhanced depth imagingDiabetesenhanced depth imaging optical coherence tomographyMiddle AgedhemangiomaAchromatic lensFemaleOriginal Articleuveal melanomanevusAdulttumorchoroidal hemangiomaCiliary bodymonosomy 3lymphomaStimulus (physiology)Color spaceAutoflouroscenceuvearetinoblastomaContrast SensitivityosteomaCavernous hemangiomaParvoMagnoResearch basedmedicinemelanomagene expression profilingHumansmetastasisChemotherapyChromatic scalemetastasesirisÓpticachromatic perimetryoptical coherence tomographyintravenous chemotherapybusiness.industryChoroidKonioSubtenon′s chemotherapyReproducibility of ResultsPattern recognitionGlaucomamedicine.diseaseAchromatic perimetrymagnoOphthalmologyglaucomaDiabetes Mellitus Type 2lcsh:RE1-994parvoOptometryVisual Field TestsAstrocytic hamartomavitreous seedsArtificial intelligenceprognosisVisual FieldsbusinessChromatic perimetrymalignancy
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Human newborns match tongue protrusion of disembodied human and robotic mouths

2011

International audience; No evidence had been provided so far of newborns' capacity to give a matching response to 2D stimuli. We report evidence from 18 newborns who were presented with three types of stimuli on a 2D screen. The stimuli were video-recorded displays of tongue protrusion shown by: (a) a human face, (b) a human tongue from a disembodied mouth, and (c) an artificial tongue from a robotic mouth. Compared to a baseline condition, neonates increased significantly their tongue protrusion when seeing disembodied human and artificial tongue movements, but not when seeing a 2D full-face protruding tongue. This result was interpreted as revealing the exploration of top-heavy patterns o…

Maleyoung infant[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionperceptionexplorationimitationTongueneonatal imitation[SDV.IDA]Life Sciences [q-bio]/Food engineeringHumans[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringpreferenceMouthGesturesmatchingnéonatalInfant NewbornRoboticsautomatic imitationNewbornImitative Behavior[SDV.AEN] Life Sciences [q-bio]/Food and NutritionFaceVisual PerceptiongestureFemalemovementartificiel[SDV.AEN]Life Sciences [q-bio]/Food and NutritionNouveau né humainmimicry
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Cambio y fundamentos literarios en el arte ruso fin-de-siècle

2011

Los orígenes del arte nuevo pueden estar relacionados con las aspiraciones de los Peredvizhniki durante la década de 1870, que había sido la creación de un arte verdaderamente nacional; por esa razón habían despreciado demasiado el tener estrechas asociaciones con los movimientos artísticos de más auge en el extranjero; sin embargo su trabajo se acercaba más a las técnicas de esos mismos grupos y a los temas de género y de pintura histórica europeos contemporáneos que a cualquier tradición artística específicamente rusa. Pero mientras que los Peredvizhniki intentaban, al igual que Tolstoi y Dostoievski, encontrar el alma de Rusia en las condiciones de la vida contemporánea, se alzó simultán…

MecenazgoUNESCO::HISTORIA::Historia por especialidades::Historia del artePintura contemporáneaInfluencia culturalLiteratura rusaRenovación literariaArt NouveauArte rusoRevistas de Arte:HISTORIA::Historia por especialidades::Historia del arte [UNESCO]
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Differential modulation and prognostic values of immune-escape genes in uveal melanoma

2019

Uveal melanoma (UM) is the most common primary intraocular cancer in adults. In the present study, we aimed to characterize the immunological features of primary UM cancer and to provide an association with prognostic markers and outcome. Also, we assessed the influence of the microenvironment on the expression of inhibitory immune checkpoints in UM. Genes of interest included MHC Class I and Class II molecules, as well as inhibitory immune-checkpoints, i.e. PDL1, PDL2, B7-H3, B7-H4, TBFRSF6B, CD47, CD155, GAL9, HVEM and CD200. We observed significant lower levels of MHC genes in UM cells as compared to normal uveal melanocytes. Unexpectedly however, the expression levels of most of the ana…

Melanomas0301 basic medicineUveal NeoplasmsGenetics and Molecular Biology (all)Gene ExpressionUveal NeoplasmPathology and Laboratory MedicineBiochemistryEpitheliumMetastasisMajor Histocompatibility ComplexWhite Blood Cells0302 clinical medicineAnimal CellsBiochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Medicine and Health SciencesImmune ResponseMelanomaMultidisciplinarybiologyT CellsMelanomaQRPrognosisGene typesOncology030220 oncology & carcinogenesisMedicineMelanocytesCellular TypesAnatomyResearch ArticleHumanPrognosiScienceImmune CellsImmunologyMHC class I genesMajor histocompatibility complex03 medical and health sciencesSigns and SymptomsImmune systemMelanocyteDiagnostic MedicineMHC class IGeneticsmedicineHumansChromatophoresInflammationBlood CellsCancers and NeoplasmsBiology and Life SciencesCancerBiochemistry; Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Epithelial CellsCell BiologyBiomarkermedicine.diseaseBiological Tissue030104 developmental biologyAgricultural and Biological Sciences (all)Cancer cellbiology.proteinCancer researchClinical ImmunologyClinical MedicineBiomarkers
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