Search results for "VAF"

R-Score: A New Parameter to Assess the Quality of Variants’ Calls Assessed by NGS Using Liquid Biopsies

2021

Next-generation sequencing (NGS) has enabled a deeper knowledge of the molecular landscape in non-small cell lung cancer (NSCLC), identifying a growing number of targetable molecular alterations in key genes. However, NGS profiling of liquid biopsies risk for false positive and false negative calls and parameters assessing the quality of NGS calls remains lacking. In this study, we have evaluated the positive percent agreement (PPA) between NGS and digital PCR calls when assessing EGFR mutation status using 85 plasma samples from 82 EGFR-positive NSCLC patients. According to our data, variant allele fraction (VAF) was significantly lower in discordant calls and the median of the absolute va…

Sarandaris traduttore di Kavafis

2018

About the first translations of Kavafis' poems into Italian by Giorgos Sarandaris

Tra gli asfodeli ...

2012

Si dimostra come il poeta Nikolas Kalas utilizzi innovativamente la simbologia dei fiori di Kavafis, ribaltandone il messaggio in senso letterariamente ed ideologicamente rivoluzionario

Accounting for Interdependent Risks in Vulnerability Assessment of Refugees

2020

The United Nations’ Vulnerability Assessment Framework (VAF) of refugees encompasses a set of indicators of the living conditions in refugee camps in Lebanon and Jordan; it assumes the independence among its components. In this paper we maintain the importance to account for existing interdependencies, and provide a definition of vulnerability for high income countries. The proposed “vulnerability scale”, based on the estimated joint risk of social isolation, economic deprivation and bad health, is a useful tool to address interventions toward selected groups of more vulnerable refugees. Analyses are based upon the survey of refugees carried on in Germany in 2016. Germany is the first count…

Kuivafermentaatiolaitos broilertilalla

2006

Kavafis e la tradizione epigrammatica greca.

2009

Saamen kielet pääomana monikielisellä Skábmagovat-elokuvafestivaalilla

2015

Anti- Toxoplasma Activities of 24 Quinolones and Fluoroquinolones In Vitro: Prediction of Activity by Molecular Topology and Virtual Computational Te…

2000

ABSTRACT The apicoplast, a plastid-like organelle of Toxoplasma gondii , is thought to be a unique drug target for quinolones. In this study, we assessed the in vitro activity of quinolones against T. gondii and developed new quantitative structure-activity relationship models able to predict this activity. The anti- Toxoplasma activities of 24 quinolones were examined by means of linear discriminant analysis (LDA) using topological indices as structural descriptors. In parallel, in vitro 50% inhibitory concentrations (IC 50 s) were determined in tissue culture. A multilinear regression (MLR) analysis was then performed to establish a model capable of classifying quinolones by in vitro acti…

Characterization of dry-film photolithography for the study of B. burgdorferi motility

2017

Kuivafilmilitografian karakterisointi Borrelia burgdorferi:n liikkuvuuden tutkimiselle. Borrelia burgdorferi on puutiaisten kantama spirokeettabakteeri, joka voi tarttua useisiin eläinlajeihin. Ihmisillä B. burgdorferi aiheuttaa borrelioosia. Tauti on laajalle levinnyt monissa pohjois- ja länsimaissa ja leviää entisestään ilmastonmuutoksen laajentaessa punkkien elinaluetta. Monet tekijät vaikeuttavat borrelioosin hoitoa. B. burgdorferin kyky välttää ihmisen luontaista immuunijärjestelmää ovat tässä suhteessa merkittävä. Bakteerien liikkuvuus on olennainen tämän kyvyn kannalta, mutta sen tarkka rooli bakteerien kyvyssä liikkua verisuonistossa on osittain tuntematon. Mikrofluidistiikka hyödyn…