Search results for "VARIATION"

Constructions of Nonagency in the Clients’ Initial Problem Formulations at the Outset of Psychotherapy

2019

This multiple case study investigated how clients construct nonagentic positions when formulating their problems in the beginning of their first psychotherapy session. The initial problem formulations of nine clients entering psychotherapy were analyzed with a detailed model drawing on discursive methodology, the 10 Discursive Tools model (10DT). We found ten problem formulation categories, each one distinguished by the tool from the 10DT model primarily used to construct nonagency. All clients gave several problem formulations from different categories and constructed nonagentic positions with a variety of discursive tools. When the resulting problem formulation categories were read in com…

The Variation of Export Prices Across and within Firms

2016

This paper uses transaction-level trade data to analyse the differences in export prices across and within Spanish manufacturing firms in the year 2014. The transactional nature of the database uncovers sizable differences in the price that an exporter charges for the same product and destination. These differences are related to the number of goods covered within each product category, volume discounts and vertically differentiated varieties. Export prices are positively correlated with firms’ productivity, destination markets’ GDP per capita and distance to Spain. These latter results suggest that Spanish exporters compete in quality.

Immunological analyses of human papillomavirus capsids

2001

Recombinant human papillomavirus (HPV) virus-like particles (VLPs) are promising vaccine candidates for controlling anogenital HPV disease. Questions remain, however, concerning the extent of capsid antigenic similarity between closely related virus genotypes. To investigate this issue, we produced VLPs and corresponding polyclonal immune sera from several anogenital HPV types, and examined these reagents in enzyme-linked immunosorbent assays (ELISAs) and in cross-neutralization studies. Despite varying degrees of L1 genetic sequence relatedness, VLPs of each type examined induced high-titer serum polyclonal antibody responses that were entirely genotype-specific. In an in vitro infectivity…

Template-Directed Protein Folding into a Metastable State of Increased Activity

1995

The principal objective of this work was to distinguish between kinetic and thermodynamic reaction control in protein folding. The deleterious effects of a specific mutation on spontaneous refolding competence were analyzed for this purpose. A Bowman-Birk-type proteinase inhibitor of trypsin and chymotrypsin was selected as a double-headed model protein to facilitate the detection of functional irregularities by the use of functional assays. The parent protein spontaneously folds into a single, fully active and thermodynamically stable state in a redox buffer after reduction/denaturation. By contrast, the properties of a P'1Ser--Pro variant in the trypsin-reactive subdomain differ before an…

Bioinformatic flowchart and database to investigate the origins and diversity of Clan AA peptidases

2009

Abstract Background Clan AA of aspartic peptidases relates the family of pepsin monomers evolutionarily with all dimeric peptidases encoded by eukaryotic LTR retroelements. Recent findings describing various pools of single-domain nonviral host peptidases, in prokaryotes and eukaryotes, indicate that the diversity of clan AA is larger than previously thought. The ensuing approach to investigate this enzyme group is by studying its phylogeny. However, clan AA is a difficult case to study due to the low similarity and different rates of evolution. This work is an ongoing attempt to investigate the different clan AA families to understand the cause of their diversity. Results In this paper, we…

La/Nb variation in Proterozoic and Mesozoic mafic dyke swarms in Brazil

1989

Contenidos obsesivos, miedo a la enfermedad y asco

2015

Recently, data about the associations between disgust and obsessive-compulsive disorder (OCD) have show some inconsistencies, which might be due to the differential role of disgust sensitivity and propensity, the infl uence of other variables, or the heterogeneity of OCD contents. This study examines the relationships among disgust sensitivity and propensity, fear of illness, and different obsessional contents in university students (N = 114). Disgust propensity was the most relevant variable in predicting Doubt/checking contents (19% of explained variance, EV), and fear of illness and disgust sensitivity were the most relevant variables predicting Contamination (EV: 21% and 8%, respectivel…

Institutional Logics and Responses to Performance Measurement Systems

2012

:  This comparative study analyzes institutional logics and categorizes organizational responses to performance measurement systems (PMSs) in two Finnish cities. We refine the typology of organizational responses and suggest how the choice of response depends on the institutionalized logic in the public sector accounting context (cf. Oliver, 1991). Further, we discuss and refine the types of successful co-operation under competing institutional logics (cf. Reay and Hinings, 2009). Our study also sheds light on practice variation in public sector accounting such as how and why PMS use materializes in different forms in units with different institutional logics.

phi-Best proximity point theorems and applications to variational inequality problems

2017

The main concern of this study is to introduce the notion of $$\varphi $$ -best proximity points and establish the existence and uniqueness of $$\varphi $$ -best proximity point for non-self mappings satisfying $$(F,\varphi )$$ -proximal and $$(F,\varphi )$$ -weak proximal contraction conditions in the context of complete metric spaces. Some examples are supplied to support the usability of our results. As applications of the obtained results, some new best proximity point results in partial metric spaces are presented. Furthermore, sufficient conditions to ensure the existence of a unique solution for a variational inequality problem are also discussed.

Fine properties of functions with bounded variation in Carnot-Carathéodory spaces

2019

Abstract We study properties of functions with bounded variation in Carnot-Caratheodory spaces. We prove their almost everywhere approximate differentiability and we examine their approximate discontinuity set and the decomposition of their distributional derivatives. Under an additional assumption on the space, called property R , we show that almost all approximate discontinuities are of jump type and we study a representation formula for the jump part of the derivative.