Search results for "VARIATION"
showing 10 items of 2124 documents
Molecular markers reflect differentiation of Fusarium oxysporum forma speciales on tomato and forma on eggplant
2013
Selective pressure induces pathogens to change their method of infection and, sometimes, causes species to become infectious. Pathogenic fungi must differentiate different morphological and physiological properties during the process of host specialization in their life cycle. In the present study, we conducted a genetic investigation and compared similarities within a generation of Fusarium oxysporum forma speciales (f. sp.) infecting tomato and forma (f.) infecting eggplants using selected ISSR and RAPD markers, two horticultural commodities belonging to the same taxon of the Solanaceae. Interestingly, genetic data showed that fungi belonging to F. oxysporum f. sp. infecting tomato have a…
Sympatric diversification vs. immigration: deciphering host-plant specialization in a polyphagous insect, the stolbur phytoplasma vector Hyalesthes o…
2012
The epidemiology of vector transmitted plant diseases is highly influenced by dispersal and the host-plant range of the vector. Widening the vector's host range may increase transmission potential, whereas specialization may induce specific disease cycles. The process leading to a vector's host shift and its epidemiological outcome is therefore embedded in the frameworks of sympatric evolution vs. immigration of preadapted populations. In this study, we analyse whether a host shift of the stolbur phytoplasma vector, Hyalesthes obsoletus from field bindweed to stinging nettle in its northern distribution range evolved sympatrically or by immigration. The exploitation of stinging nettle has l…
Molecules and morphology reveal cryptic variation among digeneans infecting sympatric mullets in the Mediterranean.
2009
SUMMARYWe applied a combined molecular and morphological approach to resolve the taxonomic status of Saccocoelium spp. parasitizing sympatric mullets (Mugilidae) in the Mediterranean. Eight morphotypes of Saccocoelium were distinguished by means of multivariate statistical analyses: 2 of Saccocoelium obesum ex Liza spp.; 4 of S. tensum ex Liza spp.; and 2 (S. cephali and Saccocoelium sp.) ex Mugil cephalus. Sequences of the 28S and ITS2 rRNA gene regions were obtained for a total of 21 isolates of these morphotypes. Combining sequence data analysis with a detailed morphological and multivariate morphometric study of the specimens allowed the demonstration of cryptic diversity thus rejecting…
Variabilité basse-fréquence des précipitations au Sahel et des températures de surface de l'océan Atlantique au cours du dernier siècle.
2012
6 pages; International audience; Cette étude examine les téléconnexions entre les températures de surface de la mer (TSM) de l'océan Atlantique et la distribution zonale des précipitations au Sahel au cours du dernier siècle. Depuis la fin des années 60, les précipitations d'Afrique de l'Ouest présentent une tendance négative sur l'ensemble de la bande sahélienne. Pourtant, trois types de variabilité basse-fréquence des précipitations sahélienne sont observés : la côte atlantique (Dakar), le Sahel central (Nioro du Sahel et Mopti) et le Sahel oriental (Niamey, Maradi, Maïné-Soroa). Au cours du XXème siècle, les précipitations sont rarement reliées simultanément avec les TSM de l'Atlantique …
Climate variability and change : hydrological impacts
2006
Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD
2007
B cell homeostasis is regulated by multiple signaling processes, including nuclear factor-kappaB (NF-kappaB), BAFF-, and B cell receptor signaling. Conditional disruption of genes involved in these pathways has shed light on the mechanisms governing signaling from the cell surface to the nucleus. We describe a novel mouse strain that expresses solely and excessively a naturally occurring splice variant of CYLD (CYLD(ex7/8) mice), which is a deubiquitinating enzyme that is integral to NF-kappaB signaling. This shorter CYLD protein lacks the TRAF2 and NEMO binding sites present in full-length CYLD. A dramatic expansion of mature B lymphocyte populations in all peripheral lymphoid organs occur…
Du comptage ponctuel à l'affectation par simulation multi-agents : application à la circulation routière de la ville de Dijon
2014
A travers une démarche expérimentale de simulation de la circulation routière pour estimer les pollutions atmosphériques en milieu urbain, cette proposition questionne les opportunités qu'offre la simulation multi-agents pour intégrer des données d'observations du trafic routier au sein d'un système d'information géographique. Pour cela, la construction du modèle d'affectation s'est faite en deux étapes : une première, d'acquisition et de structuration des données de comptages et une seconde visant à interfacer ces données au sein d'une plateforme de simulation multi-agents pour en reproduire la variabilité intra journalière et la fréquentation routière.
Altered processing of sensory stimuli in patients with migraine.
2014
Migraine is a cyclic disorder, in which functional and morphological brain changes fluctuate over time, culminating periodically in an attack. In the migrainous brain, temporal processing of external stimuli and sequential recruitment of neuronal networks are often dysfunctional. These changes reflect complex CNS dysfunction patterns. Assessment of multimodal evoked potentials and nociceptive reflex responses can reveal altered patterns of the brain's electrophysiological activity, thereby aiding our understanding of the pathophysiology of migraine. In this Review, we summarize the most important findings on temporal processing of evoked and reflex responses in migraine. Considering these d…
Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes
2013
Neuroblastoma is an embryonic tumor arising from immature sympathetic nervous system cells. Recurrent genomic alterations include MYCN and ALK amplification as well as recurrent patterns of gains and losses of whole or large partial chromosome segments. A recent whole genome sequencing effort yielded no frequently recurring mutations in genes other than those affecting ALK. However, the study further stresses the importance of DNA copy number alterations in this disease, in particular for genes implicated in neuritogenesis. Here we provide additional evidence for the importance of focal DNA copy number gains and losses, which are predominantly observed in MYCN amplified tumors. A focal 5 kb…
Calculus Artefacts in Chinese Textbooks: Variational Approaches with Prospective Primary Teachers
2022
The first part of the paper presents some theoretical reflections and some methodological notes about a Professional Development (PD) path worked out during the last two years by Italian researchers for prospective primary teachers. The theoretical construct of Cultural Transposition defines the framework of the PD path’s activities and the related research. It was used to define an interesting cultural lens to delineate possible new approaches for effective pre-service teacher education programs in particular for the primary level. The defined methodology was based on the possibility to reflect on the he decentralization of didactic practices based on a specific cultural context through on…