Search results for "VAST"
showing 10 items of 918 documents
Sustainable innovation : a new age of innovation and Finland's innovation policy
2010
Demokratia hallinnassa : hallinnan demokratisoinnin tarkastelu deliberatiivisen, osallistuvan ja vastademokratian näkökulmasta
2017
Pro gradu –tutkielmani tarkastelee hallinnan demokraattisuuden mahdollisuutta maailmassa, jossa kuva edustuksellisesta demokratiasta on horjunut. Edustuksellisen demokratian kriisi yhdistettynä hallintapuheen nousuun korostaa tarvetta uudenlaiselle tavalle ymmärtää demokraattisuutta. Demokratiapolitiikka on tuonut julkishallintoon kansalaisten osallistamisen painotuksen. Osallistuminen on olennaista myös uudenlaisissa hallinnan verkostoissa. Työssäni muodostan Eva Sörensenin ja Jacob Tofingin (2007) toimittaman teoksen Theories of Democratic Network Governance artikkelien pohjalta teoreettisen kuvan ”hallinnan maailmasta”. Se muodostaa potentiaalisen toimintaympäristön demokratialle. Työssä…
Exercise as stimulus for cartilage health in knee osteoarthritis
2018
Knee osteoarthritis (OA) is a leading cause of musculoskeletal pain and disability and has significant socio-economical costs globally. There is no known cure for OA. Therapeutic exercise has been shown to evoke acute positive posttreatment effects on pain and function. Even though cartilage degeneration is crucial in OA progression, there is sparse knowledge about exercise effects on osteoarthritic cartilage. The purpose of this study was to investigate the efficacy of aquatic resistance training on the estimated biochemical composition of tibiofemoral cartilage and the association between leisure time physical activity (LTPA) and tibiofemoral cartilage in postmenopausal women with mild kn…
Viheralueet tukevat vastasyntyneen terveyttä
2023
Kouluviihtyvyys viidesluokkalaisten kokemana
2006
Pathogenic mechanisms of how human parvovirus breaks self-tolerance
2017
It is known that viral infections can cause acute, chronic, and autoimmune diseases (ADs). However, the mechanism of how a persistent viral infection contributes to ADs remains still unclear. In this thesis, pathological and immunological aspects of how common viruses can initiate autoimmunity were investigated, and human parvovirus B19 (B19V) was employed as a model virus. B19V non-structural protein 1 (NS1), a superfamily 3 (SF3) helicase, initiated DNA damage resulting in cellular apoptosis. The apoptotic bodies (ApoBods) induced by B19V NS1 were purified and characterized. These ApoBods contained viral NS1 proteins with modified autoimmune-associated self-antigens, e.g. DNA, Smith, Apol…
Long-term strength and balance training prevents mobility decline among community-dwelling people aged 75 and older
2016
High functional capacity of muscle strength and balance in older persons promotes independent mobility and prevents functional decline below the disability threshold. This dissertation explored the effects of strength and balance training (SBT) as part of a multimodal geriatric intervention on physical functioning and health-related factors associated with training participation in a community-dwelling population aged 75 years and over. This study is a part of the Geriatric Multidisciplinary Strategy for the Good Care of the Elderly (GeMS) project conducted from 2004 to 2007 in Kuopio, Finland. Participants were randomized into an intervention (n=339) and control group (n=312). The individu…
Event-related potentials to task-irrelevant changes in facial expressions
2009
Abstract Background Numerous previous experiments have used oddball paradigm to study change detection. This paradigm is applied here to study change detection of facial expressions in a context which demands abstraction of the emotional expression-related facial features among other changing facial features. Methods Event-related potentials (ERPs) were recorded in adult humans engaged in a demanding auditory task. In an oddball paradigm, repeated pictures of faces with a neutral expression ('standard', p = .9) were rarely replaced by pictures with a fearful ('fearful deviant', p = .05) or happy ('happy deviant', p = .05) expression. Importantly, facial identities changed from picture to pi…
不同情绪面孔的视觉工作记忆表现差异 [The Performance Difference of Visual Working Memory between Various Emotional Faces]
2022
Among social-emotional stimuli, emotional faces occupy an important position, which specifically refer to human faces with certain facial expressions. The visual working memory is a limited workspace where information can be saved online and can be accessed and operated by advanced cognitive function during the maintenance period. A large number of behavioral and electrophysiological studies have shown that there are differences in visual working memory performance of different emotional faces. Specifically, angry faces can enhance the visual working memory performance; fearful faces may cause some damage to visual working memory; sad faces will impair face recognition encoding in visual wo…