Search results for "VECTOR"
showing 10 items of 2660 documents
Internalization of novel non-viral vector TAT-streptavidin into human cells
2007
Background. The cell-penetrating peptide derived from the Human immunodeficiency virus-1 transactivator protein Tat possesses the capacity to promote the effective uptake of various cargo molecules across the plasma membrane in vitro and in vivo. The objective of this study was to characterize the uptake and delivery mechanisms of a novel streptavidin fusion construct, TAT47–57-streptavidin (TAT-SA, 60 kD). SA represents a potentially useful TAT-fusion partner due to its ability to perform as a versatile intracellular delivery vector for a wide array of biotinylated molecules or cargoes. Results. By confocal and immunoelectron microscopy the majority of internalized TAT-SA was shown to accu…
Superconductivity explained with the tools of the classical electromagnetism. Educational path for secondary school and its experimentation.
2014
The work of this thesis describes an educational path for the presentation of superconductivity at the secondary school, together with the experimentation of some particular parts of the path with high school students. The educational path that we have developed is mainly centred on the phenomenological aspects of superconductivity and has been inspired by the two fluid theory of Gorter and Casimir (1934) where a superconductor is seen as a material in which two fluids are present, the normal fluid described by the Ohm's laws, and the superconductive fluid descibed by the London equation (1935). Both the Ohm's laws and the London equation give respectively the phenomenological descriptions …
On the spectrum of semi-classical Witten-Laplacians and Schrödinger operators in large dimension
2005
We investigate the low-lying spectrum of Witten–Laplacians on forms of arbitrary degree in the semi-classical limit and uniformly in the space dimension. We show that under suitable assumptions implying that the phase function has a unique local minimum one obtains a number of clusters of discrete eigenvalues at the bottom of the spectrum. Moreover, we are able to count the number of eigenvalues in each cluster. We apply our results to certain sequences of Schrodinger operators having strictly convex potentials and show that some well-known results of semi-classical analysis hold also uniformly in the dimension.
An explicit unconditionally stable numerical solution of the advection problem in irrotational flow fields
2004
[1] A new methodology for the Eulerian numerical solution of the advection problem is proposed. The methodology is based on the conservation of both the zero- and the first-order spatial moments inside each element of the computational domain and leads to the solution of several small systems of ordinary differential equations. Since the systems are solved sequentially (one element after the other), the method can be classified as explicit. The proposed methodology has the following properties: (1) it guarantees local and global mass conservation, (2) it is unconditionally stable, and (3) it applies second-order approximation of the concentration and its fluxes inside each element. Limitati…
Champs de vecteurs analytiques commutants, en dimension 3 ou 4: existence de zeros communs
1992
One proves the existence of a common zero for any two ℝ-analytic commuting vector fields on a 4-dimensional manifold with not zero Euler characteristic. A local version of this result remains true on 3-manifolds.
On Stability of a Concentrated Fiber Suspension Flow
2014
Linear stability analysis of a fiber suspension flow in a channel domain is performed using a modified Folgar-Tucker equation. Two kinds of potential instability are identified: one is associated with overcritical Reynolds number and another is associated with certain perturbations in fiber orientation field and is present for any Reynolds numbers. The second type of instability leads to initially growing transient perturbations in the microstructure. It is shown that both types of instability lead to instability of the bulk velocity field. As for the perturbed Orr-Sommerfeld eigenvalues, the presence of fibers increases the stability region; the stability region increases with growing C i …
Modal analysis for random response of MDOF systems
1990
The usefulness of the mode-superposition method of multidegrees of freedom systems excited by stochastic vector processes is here presented. The differential equations of moments of every order are written in compact form by means of the Kronecker algebra; then the method for integration of these equations is presented for both classically and non-classically damped systems, showing that the fundamental operator available for evaluating the response in the deterministic analysis is also useful for evaluating the response in the stochastic analysis.
Spectral Asymptotics for More General Operators in One Dimension
2019
In this chapter, we generalize the results of Chap. 3. The results and the main ideas are close, but not identical, to the ones of Hager (Ann Henri Poincare 7(6):1035–1064, 2006). We will use some h-pseudodifferential machinery, see for instance Dimassi and Sjostrand (Spectral Asymptotics in the Semi-classical Limit, London Mathematical Society Lecture Note Series, vol 268. Cambridge University Press, Cambridge, 1999).
Distribution of Large Eigenvalues for Elliptic Operators
2019
In this chapter we consider elliptic differential operators on a compact manifold and rather than taking the semi-classical limit (h →), we let h = 1 and study the distribution of large eigenvalues. Bordeaux Montrieux (Loi de Weyl presque sure et resolvante pour des operateurs differentiels non-autoadjoints, these, CMLS, Ecole Polytechnique, 2008. https://pastel.archives-ouvertes.fr/pastel-00005367, Ann Henri Poincare 12:173–204, 2011) studied elliptic systems of differential operators on S1 with random perturbations of the coefficients, and under some additional assumptions, he showed that the large eigenvalues obey the Weyl law almost surely. His analysis was based on a reduction to the s…
Computing the Trace
2001
So far we have been interested in the general expression for the WKB-propagation function. Now we turn our attention to the trace of that propagator, since we want to exhibit the energy eigenvalues of a given potential. From earlier discussions we know that the energy levels of a given Hamiltonian are provided by the poles of the Green’s function: