Search results for "VECTOR"
showing 10 items of 2660 documents
Cloning and characterization of Scavidin, a fusion protein for the targeted delivery of biotinylated molecules.
2001
We have constructed a novel fusion protein "Scavidin" consisting of the macrophage scavenger receptor class A and avidin. The Scavidin fusion protein is transported to plasma membranes where the avidin portion of the fusion protein binds biotin with high affinity and forms the basis for the targeted delivery of biotinylated molecules. Subcellular fractionation analysis, immunostaining, and electron microscopy demonstrated endosomal localization of the fusion protein. According to pulse-labeling and cross-linking studies Scavidin is found as monomers (55 kDa), dimers, and multimers, of which the 220-kDa form was the most abundant. The biotin binding capacity and active endocytosis of the bio…
Detection of tick-borne encephalitis virus in I. ricinus ticks collected from autumn migratory birds in Latvia.
2014
Birds have a potential of spreading ticks via bird migration routes. In this study, we screened 170 ticks removed during autumn 2010 from 55 birds belonging to 10 species for the presence of tick-borne encephalitis virus (TBEV). In total, TBEV RNA was detected in 14% of I. ricinus tick samples obtained from different birds species. The results of this study indicate the possible role of migrating birds in the dispersal of TBEV-infected ticks along the southward migration route.
Experimental and theoretical study of the nonlinear birefringence in the formation process of vector solitons in a total polarization control ring ca…
2022
Abstract In this work, we present the numerical and experimental investigation of the polarization dynamics in a free birefringence mode-locked fiber laser. The laser includes a double-pass Erbium-doped fiber amplifier and 20-m long bi-twisted fiber at a twist rate of ± 6 turns m−1 to mitigate both, linear and circular birefringence effects. We found ellipticity changes due to nonlinear birefringence in the 20-m long fiber during pulse formation and propagation. In contrast with previously reported works, the inclusion of bi-twisted fiber allows investigate the nonlinear effects independently from the linear ones. The experimental behavior was confirmed by numerical simulations based on spl…
Sparse Deconvolution Using Support Vector Machines
2008
Sparse deconvolution is a classical subject in digital signal processing, having many practical applications. Support vector machine (SVM) algorithms show a series of characteristics, such as sparse solutions and implicit regularization, which make them attractive for solving sparse deconvolution problems. Here, a sparse deconvolution algorithm based on the SVM framework for signal processing is presented and analyzed, including comparative evaluations of its performance from the points of view of estimation and detection capabilities, and of robustness with respect to non-Gaussian additive noise. Publicado
Iterative sparse matrix-vector multiplication for accelerating the block Wiedemann algorithm over GF(2) on multi-graphics processing unit systems
2012
SUMMARY The block Wiedemann (BW) algorithm is frequently used to solve sparse linear systems over GF(2). Iterative sparse matrix–vector multiplication is the most time-consuming operation. The necessity to accelerate this step is motivated by the application of BW to very large matrices used in the linear algebra step of the number field sieve (NFS) for integer factorization. In this paper, we derive an efficient CUDA implementation of this operation by using a newly designed hybrid sparse matrix format. This leads to speedups between 4 and 8 on a single graphics processing unit (GPU) for a number of tested NFS matrices compared with an optimized multicore implementation. We further present…
A double mean field equation related to a curvature prescription problem
2019
We study a double mean field-type PDE related to a prescribed curvature problem on compacts surfaces with boundary. We provide a general blow-up analysis, then a Moser-Trudinger inequality, which gives energy-minimizing solutions for some range of parameters. Finally, we provide existence of min-max solutions for a wider range of parameters, which is dense in the plane if $��$ is not simply connected.
Fascioliasis in Llama, Lama glama, in Andean Endemic Areas: Experimental Transmission Capacity by the High Altitude Snail Vector Galba truncatula and…
2021
Simple Summary The infection by the liver fluke Fasciola hepatica in South American camelids, mainly llamas and alpacas, has been the focus of many studies. However, their capacity to participate in the transmission of the disease and their potential reservoir role in human or animal endemic areas have never been studied. Therefore, all development stages of an isolate from Argentine llama of the high Andean plateau have been experimentally investigated, from egg embryogenesis to metacercarial infectivity, by using the vector snail Galba truncatula from the high altitude Bolivian Altiplano human hyperendemic area. Although eggs shed by llamas may successfully develop until the adult stage i…
Aplicação do conceito One Health na área hiperendêmica de fasciolíase humana do Altiplano Boliviano: biologia dos limneídeos, dinâmica populacional, …
2021
Abstract Fascioliasis is a freshwater snail-borne zoonotic disease. The Northern Bolivian Altiplano is a very high altitude endemic area where the highest human prevalences and intensities have been reported. Preventive chemotherapy by treatment campaigns is yearly applied. However, liver fluke infection of cattle, sheep, pigs and donkeys assures endemicity and consequent human infection and re-infection risks. A One Health action has therefore been implemented. Activity concerns lymnaeid vectors and environment diversity. Studies included growth, egg-laying and life span in laboratory-reared lymnaeids. Different habitat types and influencing factors were assessed. All populations proved to…
Sheep and Cattle Reservoirs in the Highest Human Fascioliasis Hyperendemic Area: Experimental Transmission Capacity, Field Epidemiology, and Control …
2020
The Northern Bolivian Altiplano is the human fascioliasis hyperendemic area where the highest prevalences and intensities of infection by Fasciola hepatica in humans have been reported. Four animal species are the reservoir species for F. hepatica in this area, namely, sheep, cattle, pigs, and donkeys. Livestock for the Aymara inhabitants is crucial because vegetable cultures are not viable due to the inhospitality of the very high altitude of 3,820–4,100 m. A One Health initiative has been implemented in this area in recent years, as the first such control action in a human endemic area ever. Among the different control axes included, special focus is devoted to the two main reservoirs she…
Processing of rock core microtomography images: Using seven different machine learning algorithms
2016
The abilities of machine learning algorithms to process X-ray microtomographic rock images were determined. The study focused on the use of unsupervised, supervised, and ensemble clustering techniques, to segment X-ray computer microtomography rock images and to estimate the pore spaces and pore size diameters in the rocks. The unsupervised k-means technique gave the fastest processing time and the supervised least squares support vector machine technique gave the slowest processing time. Multiphase assemblages of solid phases (minerals and finely grained minerals) and the pore phase were found on visual inspection of the images. In general, the accuracy in terms of porosity values and pore…