Search results for "VERTICILLIOIDES"

showing 3 items of 3 documents

Transcription of genes in the biosynthetic pathway for fumonisin mycotoxins is epigenetically and differentially regulated in the fungal maize pathog…

2012

ABSTRACT When the fungal pathogen Gibberella moniliformis (anamorph, Fusarium verticillioides ) colonizes maize and maize-based products, it produces class B fumonisin (FB) mycotoxins, which are a significant threat to human and animal health. FB biosynthetic enzymes and accessory proteins are encoded by a set of clustered and cotranscribed genes collectively named FUM, whose molecular regulation is beginning to be unraveled by researchers. FB accumulation correlates with the amount of transcripts from the key FUM genes, FUM1 , FUM21 , and FUM8 . In fungi in general, gene expression is often partially controlled at the chromatin level in secondary metabolism; when this is the case, the deac…

DISRUPTIONTranscription GeneticFUM21[SDV]Life Sciences [q-bio]DIVERSITYPROTEINFusarium verticillioidesmaizeSECONDARY METABOLISMgene clusterEpigenesis GeneticHistonesFUM8FusariumGene Expression Regulation FungalASPERGILLUSPromoter Regions Genetic2. Zero hungerGenetics0303 health sciencesHistone deacetylase inhibitorhistone acetylationAcetylationArticlesGeneral MedicineChromatinChromatinGENOMEHistoneMultigene Family[SDE]Environmental SciencesTrichostatin AEpigenetics; Fusarium verticillioides; fmonisin synthesismedicine.drugCONIDIATIONChromatin Immunoprecipitationmedicine.drug_classGenes FungalChIPBiologyGFPZea maysMicrobiologyFumonisinsChromatin remodeling03 medical and health sciencesmedicineEpigeneticsMolecular Biology030304 developmental biologyepigenetics030306 microbiologyCLUSTERFumonisins; epigenetics; Fusarium verticillioides; maize; histone acetylation; histone deacetylases; ChIP; Trichostatin A; FUM1; FUM21; FUM8; GFP; gene clusterMycotoxinsChromatin Assembly and DisassemblyFUM1Histone Deacetylase InhibitorsTrichostatin AAcetylationbiology.proteinChromatin immunoprecipitationhistone deacetylases
researchProduct

Isolation, purification, LC–MS/MS characterization and reactive oxygen species induced by fumonisin B1 in VERO cells

2010

Fumonisins are mycotoxins produced by Fusarium verticillioides that commonly contaminate maize and maize products. The present work shows the results of a comparative study of three different fermentation's techniques (solid and liquid medium of corn and a solid agarized medium) for the production of fumonisins B-1, B-2 and B-3 with strains of F. verticillioides. The solid medium of corn was the most effective in the production of fumonisins, being Fumonisin B-1 the one produced with higher concentration, so the extract obtained by solid fermentation process was used for FB1 purification. Fumonisins characterization and quantification were performed with reversed-phase high-performance liqu…

FusariumEXTRACTIONVERTICILLIOIDESCULTURESToxicologyFumonisinsMECHANISMSchemistry.chemical_compoundFUSARIUM-MONILIFORMEFusariumTandem Mass SpectrometryLiquid chromatography–mass spectrometryDichlorofluoresceinChlorocebus aethiopsFumonisinAnimalsOXIDATIVE STRESSMycotoxinVero CellsChromatography High Pressure LiquidPROLIFERATUMFumonisin B1ChromatographyMYCOTOXINSbiologyfood and beveragesGeneral MedicineReference StandardsFluoresceinsbiology.organism_classificationCulture MediaDNA-DAMAGEchemistryFermentationVero cellFermentationOCHRATOXINReactive Oxygen SpeciesFood ScienceFood and Chemical Toxicology
researchProduct

Open Field Study of Some Zea mays Hybrids, Lipid Compounds and Fumonisins Accumulation

2015

Lipid molecules are increasingly recognized as signals exchanged by organisms interacting in pathogenic and/or symbiotic ways. Some classes of lipids actively determine the fate of the interactions. Host cuticle/cell wall/membrane components such as sphingolipids and oxylipins may contribute to determining the fate of host–pathogen interactions. In the present field study, we considered the relationship between specific sphingolipids and oxylipins of different hybrids of Zea mays and fumonisin by F. verticillioides, sampling ears at different growth stages from early dough to fully ripe. The amount of total and free fumonisin differed significantly between hybrids and increased significantl…

FusariumoxylipinsHealth Toxicology and MutagenesisCuticlelcsh:MedicineFood ContaminationFusarium verticillioidesmaizeFumonisinsZea maysArticlemycotoxinCell wallchemistry.chemical_compoundFusariumFumonisinBotanyMycotoxinsphingolipidsbiologylcsh:Rfood and beveragesRipeningLipidomebiology.organism_classificationSphingolipidFusarium verticillioides; maize; mycotoxin; oxylipins; sphingolipids; food contamination; food microbiology; fumonisins; fusarium; host-pathogen interactions; Oxylipins; sphingolipids; Zea mays; toxicology; health toxicology and mutagenesishealth toxicology and mutagenesischemistryBiochemistryHost-Pathogen InteractionsFood MicrobiologySettore AGR/12 - PATOLOGIA VEGETALE<i>Fusarium verticillioides</i>toxicologyToxins
researchProduct