Search results for "VILDAGLIPTĪNS"

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Development and validation of the HPLC method for determination of vildagliptin content and impurities

2015

Vildagliptīna satura un blakuspiemaisījumu satura noteikšanas AEŠH metodes izstrāde un validācija. Paškova O., zinātniskie vadītāji Dr. Chem. Bolotin A., Dr. Chem. Mekšs P., Maģistra darbs, 86 lappuses, 34 attēli, 52 tabulas, 26 literatūras avoti, 4 pielikumi. Latviešu valodā. Vildagliptīns ir jaunas klases antidiabētiskais preparāts. Katrai AFV jāzin tās saturs un piemaisījumu daudzums, jo no tā ir atkarīga medikamenta iedarbība. Darbā tika izstrādātas AEŠH/UV metodes pamatvielas satura un piemaisījumu satura noteikšanai vildagliptīnā, kā arī tika veikta šo metožu validācija. Darbā tika pieradīts, ka metodes lineāras, precīzas, pareizas un robustas, noteiktas detektēšanas un kvantitatīvās …

VALIDĀCIJAAEŠHVILDAGLIPTĪNSDEGRADĀCIJAPIEMAISĪJUMIĶīmija

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PEPhysical Sciences and Engineering
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