Search results for "VISION"

showing 10 items of 5066 documents

Leukocytes in neuronal ceroid-lipofuscinoses: function and apoptosis

1997

The neuronal ceroid-lipofuscinoses (NCL) are a group of progressive encephalopathies with a fatal course that are mostly of autosomal recessive inheritance. The pathophysiological mechanisms causing the diseases are not known. The characteristic histomorphological feature of the NCL is an abnormal lysosomal accumulation of lipopigments in neural and extraneural cells, including peripheral blood leukocytes. We studied the function of peripheral venous blood immunocompetent cells in ten patients with NCL and in age- and sex-matched controls to determine how, if at all, the accumulation of intracytoplasmic storage material influences the functional capacity of affected tissue. Our results did …

AdultMaleProgrammed cell deathPathologymedicine.medical_specialtyAdolescentmedicine.medical_treatmentImmunoglobulinsApoptosisImmunoglobulin EImmunophenotypingPathogenesisDevelopmental NeuroscienceNeuronal Ceroid-LipofuscinosesSuperoxidesLeukocytesmedicineHumansChildRespiratory BurstbiologyInterleukin-6Interleukin-8General Medicinemedicine.diseasePathophysiologyCytokineApoptosisChild PreschoolPediatrics Perinatology and Child HealthImmunologybiology.proteinFemaleNeuronal ceroid lipofuscinosisNeurology (clinical)AntibodyBiomarkersCell DivisionInterleukin-1Brain and Development
researchProduct

Axis Rotation and Visually Induced Motion Sickness: The Role of Combined Roll, Pitch, and Yaw Motion

2011

A well-known phenomenon in aviation and in virtual environments such as simulators or computer games is motion sickness (MS). The amount of sensory conflict is thought to be responsible for the severity of MS, which should increase with the complexity of the simulated motion. The focus of the present study is on the direction and complexity of simulated body rotations in the genesis and severity of visually induced MS. The methods utilized for this study are as follows: Three simulated rollercoaster rides including translational movement in the fore-aft axis and additional rotational motion either in pitch only, along the pitch and roll axes, or in pitch, roll, and yaw were generated. The a…

AdultMaleProjection screenVisual perceptionRotationMotion SicknessMovementSeverity of Illness IndexFlight dynamicsmedicineHumansComputer visionVerbal Rating ScaleSimulationMathematicsAnalysis of Variancebusiness.industryPublic Health Environmental and Occupational HealthRotation around a fixed axisVideotape Recordingmedicine.diseaseMotion sicknessVisual PerceptionSimulator sicknessFemaleArtificial intelligenceFast motionbusinessAviation, Space, and Environmental Medicine
researchProduct

Some physiological and psychological characteristics of myopic and non-myopic young men.

2009

As a part of a research project on the health and functional capacity of men at different ages a comparison of selected physiological and psychological characteristics of myopic and non-myopic 31–35 year-old men was made. The random sample studied consisted of 31 myopic and 100 non-myopic men. It was found that the body mass index and fat content were lower among the myopic than among the non-myopic. No significant differences were found in the elastic properties of skin, in blood pressure or in haematological assays studied between the groups. With respect to physical performance it was observed that the myopic had a higher aerobic capacity whereas there were no significant differences in …

AdultMalePsychological Testsgenetic structuresAnthropometryFat contentPhysical activityDark AdaptationGeneral MedicineAnthropometryeye diseasesAmplitude of accommodationOphthalmologyCognitionPhysical performanceMyopiaOptometryHumanssense organsPsychologyBody mass indexVision OcularDemographyActa ophthalmologica. Supplement
researchProduct

Chronic T cell leukemia with unusual cellular characteristics in ataxia telangiectasia

1986

Abstract A 27-year-old male patient with ataxia telangiectasia (AT) developed atypical chronic lymphocytic leukemia with increasing bone marrow infiltration in the absence of organomegaly. One-third of the leukemia cells expressed a mature suppressor/cytotoxic T cell phenotype (T3+ T4- T6- T8+ T10-), two-thirds demonstrated additional helper/inducer T cell- associated antigens (T3+ T4+ T6- T8+ T10-), and a small fraction reacted with a natural killer (NK) cell-specific monoclonal antibody (Leu 11+). The proliferative response to stimulation in vitro with lectins and various monoclonal antibodies resembled the proliferation pattern of mature thymocytes: The cells responded to phytohemaggluti…

AdultMaleReceptor complexChronic lymphocytic leukemiaT cellT-LymphocytesImmunologyBiochemistryAtaxia TelangiectasiaAntigenmedicineCytotoxic T cellHumansLeukemiabiologyAntibody-Dependent Cell CytotoxicityCell BiologyHematologymedicine.diseaseMolecular biologyKiller Cells NaturalLeukemiamedicine.anatomical_structurePhenotypeConcanavalin AKaryotypingAtaxia-telangiectasiaImmunologyChronic Diseasebiology.proteinLymphocyte Culture Test MixedCell DivisionBlood
researchProduct

An alternative clinical routine for subjective refraction based on power vectors with trial frames.

2016

PURPOSE Subjective refraction determines the final point of refractive error assessment in most clinical environments and its foundations have remained unchanged for decades. The purpose of this paper is to compare the results obtained when monocular subjective refraction is assessed in trial frames by a new clinical procedure based on a pure power vector interpretation with conventional clinical refraction procedures. METHODS An alternative clinical routine is described that uses power vector interpretation with implementation in trial frames. Refractive error is determined in terms of: (i) the spherical equivalent (M component), and (ii) a pair of Jackson Crossed Cylinder lenses oriented …

AdultMaleRefractive errorCorrelation coefficientAdolescentVisual AcuityAstigmatismRefraction Ocular01 natural sciences010309 optics03 medical and health sciencesYoung Adult0302 clinical medicineOptics0103 physical sciencesmedicineHumansPhoropterMathematicsMonocularbusiness.industryOrientation (computer vision)Vision TestsEquipment Designmedicine.diseaseRefractive ErrorsSubjective refractionRefractionSensory SystemsOphthalmologyEyeglasses030221 ophthalmology & optometryFemalebusinessAlgorithmOptometryOphthalmicphysiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
researchProduct

Mesopic contrast sensitivity function after excimer laser photorefractive keratectomy.

2002

ABSTRACT PURPOSE: To evaluate contrast sensitivity under mesopic conditions in patients who had undergone uncomplicated excimer laser photorefractive keratectomy (PRK) for myopia. METHODS: Monocular contrast sensitivity function was measured with the Stereo Optical ?A.C.T. chart in 26 patients who had received PRK using the Nidek EC-5000 excimer laser system. Mean preoperative refractive error was -6.23 ? 1.69 D (range, -4.00 to -8.25 D); postoperatively, mean refractive error was -0.36 ? 0.58 D (range, -0.75 to +0.50 D). Contrast sensitivity function was measured 6 months after surgery using four different chart luminances: 85, 5.0, 2.5, and 0.1 cd/m2, the first being a photopic level and …

AdultMaleRefractive errormedicine.medical_specialtyMaterials scienceLightMesopic visionmedicine.medical_treatmentmedia_common.quotation_subjectVisual AcuityEmmetropiaRefraction OcularExcimerPhotorefractive KeratectomyContrast SensitivityOpticsOphthalmologyMyopiamedicineHumansContrast (vision)media_commonExcimer laserbusiness.industrymedicine.diseaseeye diseasesPhotorefractive keratectomyOphthalmologyFemaleLasers ExcimerSurgerybusinessPhotopic vision
researchProduct

Mesopic Contrast Sensitivity Function After Laser in situ Keratomileusis

2003

ABSTRACT PURPOSE: To evaluate contrast sensitivity under mesopic conditions in patients who have undergone uncomplicated bilateral laser in situ keratomileusis (LASIK) for myopia. METHODS: Best-corrected monocular contrast sensitivity was measured with the Stereo Optical F.A.C.T. chart at 1.5, 3, 6, 12, and 18 c/deg in 20 patients (20 left eyes) before and after bilateral LASIK (with the Nidek EC-5000 excimer laser and the Automated Corneal Shaper). Mean preoperative refractive error was -6.40 ± 1.28 D (range -4.00 to -8.00 D) and postoperative mean refractive error was -0.41 ± 0.45 D (range -0.75 to +0.50 D). Contrast sensitivity function was measured before and 6 months after surgery usin…

AdultMaleRefractive errormedicine.medical_specialtyMaterials scienceLightgenetic structuresMesopic visionEye diseasemedia_common.quotation_subjectmedicine.medical_treatmentKeratomileusis Laser In SituKeratomileusisContrast SensitivityCorneaVision disorderOphthalmologyMyopiamedicineHumansContrast (vision)media_commonLASIKmedicine.diseaseeye diseasesSurgeryOphthalmologyFemaleSurgerysense organsmedicine.symptomPhotopic visionJournal of Refractive Surgery
researchProduct

Iris Claw Phakic Intraocular Lens for High Myopia

1997

ABSTRACT BACKGROUND: The implantation of a WorstFechner iris claw intraocular lens (IOL) is one of the surgical procedures used for the correction of high myopia. This technique reduces myopia with stähle refractive results; however, its potential long-term risks have not been evaluated. We report results in 94 eyes with a minimum follow -up of 3 years. METHODS: We studied 94 eyes of 62 patients with myopia 5= -7.00 diopters (D) who underwent Worst-Fechner IOL implantation. Lens decentration, permeability of the blood-aqueous barrier by iris angiography, and changes in corneal endothelial density were analyzed. RESULTS: Mean follow-up time was 48.9 months (range 36 to 72 mo). Three years af…

AdultMaleRefractive errormedicine.medical_specialtyTime FactorsVisual acuitygenetic structuresEye diseasemedicine.medical_treatmentVisual AcuityIrisEmmetropiaIntraocular lensRefraction OcularPhakic intraocular lensVision disorderPostoperative ComplicationsOphthalmologyMyopiamedicineHumansDioptreAgedRetrospective StudiesLenses Intraocularbusiness.industryEndothelium CornealMiddle Agedmedicine.diseaseeye diseasesOphthalmologyTreatment OutcomeFemaleSurgerysense organsmedicine.symptombusinessFollow-Up StudiesJournal of Refractive Surgery
researchProduct

Long-term results of surgical treatment of high myopia with Worst-Fechner intraocular lenses

1995

Abstract This retrospective study evaluated the results in 90 eyes that had a minus-power anterior chamber intraocular lens implanted to correct high myopia. Preoperative myopia ranged from −7.00 to −24.00 D. Postoperative spherical equivalent was −0.50 D; 80.5% of eyes were within 1.00 D of emmetropia. Two years postoperatively, no cataract formation, retinal detachment, glaucoma, or significant endothelial damage had occurred. We conclude that minus-power lenses can rapidly, safely, and predictably correct high myopia in phakic patients.

AdultMaleRefractive errormedicine.medical_specialtygenetic structuresAnterior ChamberEye diseasemedicine.medical_treatmentVisual AcuityEmmetropiaGlaucomaIntraocular lensProsthesis DesignVision disorderPostoperative ComplicationsOphthalmologyMyopiamedicineHumansLongitudinal StudiesAgedRetrospective StudiesLenses Intraocularbusiness.industryRetinal detachmentRetrospective cohort studyMiddle AgedPrognosismedicine.diseaseeye diseasesSensory SystemsOphthalmologyFemaleSurgerysense organsmedicine.symptombusinessFollow-Up StudiesJournal of Cataract and Refractive Surgery
researchProduct

Excimer laser photorefractive keratectomy for high myopia

1995

Abstract One hundred and thirty-three eyes of 103 patients had photorefractive keratectomy with a slit scan mode excimer laser for myopia ranging from −6.00 to −22.00 diopters (D). The epithelium was removed with 20% ethanol, and the ablation was done with a tapered profile surrounding the optical zone. Patients were divided into two groups based on preoperative myopia: Group A, −6.00 D to −12.00 D (88 eyes); Group B, −12.50 D to −22.00 D (45 eyes). In Group A, mean preoperative refraction was −9.59 ± 1.79 D. Mean postoperative refraction was −0.29 ± 1.47 D at one month, −0.85 ± 1.68 D at three months, −1.17 ± 2.04 D at six months, and −0.56 ± 0.74 D at one year. Anterior stromal haze was g…

AdultMaleRefractive errormedicine.medical_specialtygenetic structuresCorneal Stromamedicine.medical_treatmentEye diseaseVisual AcuityRefraction OcularExcimerPhotorefractive KeratectomyEpitheliumCorneaVision disorderCorneal OpacityOphthalmologyMyopiamedicineHumansIntraocular PressureDioptreExcimer laserbusiness.industryMiddle AgedPrognosismedicine.diseaseAblationeye diseasesSensory SystemsPhotorefractive keratectomyOphthalmologyFemaleLasers ExcimerSurgerysense organsmedicine.symptombusinessJournal of Cataract and Refractive Surgery
researchProduct