Search results for "VOLTAGE"

Persistent activity in layer 5 pyramidal neurons following cholinergic activation of mouse primary cortices

2011

Persistent spiking activity is thought to be a cellular process involved in working memory. We have been interested in whether persistent activity also exists in cortical areas which are not involved in this memory process. To study the possible presence and the mechanisms of persistent activity in layer 5 pyramidal cells of the mouse primary somatosensory, visual and motor cortices, we used patch-clamp and calcium imaging techniques. A combination of cholinergic receptor activation and suprathreshold depolarization or sufficient extracellular stimulation leads to either a subthreshold afterdepolarization or suprathreshold persistent activity in these cortices. There is a continuum of respo…

Co-expression of the voltage-gated potassium channel Kv1.4 with transient receptor potential channels (TRPV1 and TRPV2) and the cannabinoid receptor …

2006

Potassium channels contribute to basic neuronal excitability and modulation. Here, we examined expression patterns of the voltage-gated potassium channel Kv1.4, the nociceptive transduction channels TRPV1 and TRPV2 as well as the putative anti-nociceptive cannabinoid receptor CB1 by immunofluorescence double-labelings in sections of rat dorsal root ganglia (DRGs). Kv1.4, TRPV1 and CB1 were each detected in about one third of neurons (35.7+/-0.5%, 29.4+/-1.1% and 36.4+/-0.5%, respectively, mean diameter 19.1+/-0.3 microm). TRPV2 was present in 4.4+/-0.4% of all neurons that were significantly larger in diameter (27.4+/-0.7 microm; P < 0.001). Antibody double-labeling revealed that the majori…

Power-Line Communication in Medium-Voltage System: Simulation Model and Onfield Experimental Tests

2012

The aim of this paper is to develop a complete model of a power-line communication (PLC) system operating on a medium-voltage (MV) network. The core-shield configuration was chosen for signal transmission in the power cables. In order to validate the developed model experimental, the medium-voltage network of the Favignana island was used to carry out detailed testing. The transmission was performed between two transformer substations in the presence of mains voltage (i.e., 24 kV). ST7540 FSK power-line transceivers, together with capacitive coupling interfaces, were used for the transmission and the reception of the communication signal. The correlation between the experimental measurement…

Effect of low amount of nanosilica on dielectric properties of polypropylene

2010

This paper presents the results of the dielectric properties measurements conducted on Silica-Polypropylene (PP) nanocomposites. According to prior investigations by the authors silica nanoparticles have improved the performance of the dielectric material considering capacitor applications. Especially breakdown strengths with ac and dc voltages and resistance against surface degradation have increased. The relative permittivity and dielectric losses have also been comparable to reference PP. In this paper the results of the dielectric measurements conducted on composites with 1-2 wt-% silica are compared with reference PP. Silica dispersion in PP was confirmed with transmission electron mic…

Odorant binding changes the electrical properties of olfactory receptors at the nanoscale

2021

Olfactory receptors (ORs) comprise the largest multigene family in the vertebrates. They belong to the class A (rhodopsin-like) family of G protein-coupled receptors (GPCRs), which are the most abundant membrane proteins, having widespread, significant roles in signal transduction in cells, and therefore, they are a major pharmacological target. Moreover, ORs displayed high selectivity and sensitivity towards odorant detection, a characteristic that raised the interest for developing biohybrid sensors based on ORs for the detection of volatile compounds. The transduction of odorant binding into cellular signaling by ORs is not well understood and knowing its mechanism would enable developin…

The electrophysiology of adenosine in the mammalian central nervous system

1991

Adaptive Mechanisms of Somatostatin-Positive Interneurons after Traumatic Brain Injury through a Switch of α Subunits in L-Type Voltage-Gated Calcium…

2021

Abstract Unilateral traumatic brain injury (TBI) causes cortical dysfunctions spreading to the primarily undamaged hemisphere. This phenomenon, called transhemispheric diaschisis, is mediated by an imbalance of glutamatergic versus GABAergic neurotransmission. This study investigated the role of GABAergic, somatostatin-positive (SST) interneurons in the contralateral hemisphere 72 h after unilateral TBI. The brain injury was induced to the primary motor/somatosensory cortex of glutamate decarboxylase 67–green fluorescent protein (GAD67-GFP) knock-in mice at postnatal days 19–21 under anesthesia in vivo. Single GFP+ interneurons of the undamaged, contralateral cortex were isolated by fluores…

Observable Electric Potential and Electrostatic Potential in Electrochemical Systems

1999

The role of the electric potential in the description of transport processes in electrochemical systems is critically analyzed. Since the electrostatic potential drop between two parts of a system ...

Operational Mechanism of Conjugated Polyelectrolytes

2014

Conjugated polyelectrolytes (CPEs) are versatile materials used in a range of organic optoelectronic applications. Because of their ionic/electronic nature, characterizing these materials is nontrivial, and their operational mechanism is not fully understood. In this work we use a methodology that combines constant-voltage-driven current-density transient measurements with fast current vs voltage scans to allow decoupling of ionic and electronic phenomena. This technique is applied to diodes prepared with cationic CPEs having different charge-compensating anions. Our results indicate that the operational mechanism of these devices is governed by electrochemical doping of the CPE. On the bas…

Electrostatic field theory and circuit analysis in the design of coalescers with pulsed dc voltage

2009

This paper presents a mathematical analysis of the electric field and interfacial free charge experienced by the emulsion in an electrostatic coalescer that is subjected to a pulsed dc voltage. Previous work in this area is re-assessed, but the analysis is expanded. A novel static analysis of the system is presented, giving valuable physical insight. It becomes obvious that there must be a limited range of frequencies that are effective in a pulsed dc scheme. Thereafter, analytical expressions for the steady-state solution, where both the switching frequency and duty ratio (or mark space ratio) can be varied, are presented for the first time. These expressions are used to derive voltage and…