Search results for "Vala"
showing 10 items of 162 documents
Pharmacological Properties of Polyphenols: Bioavailability, Mechanisms of Action, and Biological Effects in In Vitro Studies, Animal Models, and Huma…
2021
Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2227-9059/9/8/1074 Este artículo de investigación pertenece al número especial "Oxidative Stress and Inflammation: From Mechanisms to Therapeutic Approaches 2.0". Drugs are bioactive compounds originally discovered from chemical structures present in both the plant and animal kingdoms. These have the ability to interact with molecules found in our body, blocking them, activating them, or increasing or decreasing their levels. Their actions have allowed us to cure diseases and improve our state of health, which has led us to increase the longevity of our species. Among the molecules with pharmacological activity …
Beam test measurements of Low Gain Avalanche Detector single pads and arrays for the ATLAS High Granularity Timing Detector
2018
For the high luminosity upgrade of the LHC at CERN, ATLAS is considering the addition of a High Granularity Timing Detector (HGTD) in front of the end cap and forward calorimeters at |z|= 3.5 m and covering the region 2.4 <|η|< 4 to help reducing the effect of pile-up. The chosen sensors are arrays of 50 μm thin Low Gain Avalanche Detectors (LGAD). This paper presents results on single LGAD sensors with a surface area of 1.3×1.3 mm2 and arrays with 2×2 pads with a surface area of 2×2 mm2 or 3×3 mm2 each and different implant doses of the p+ multiplication layer. They are obtained from data collected during a beam test campaign in autumn 2016 with a pion beam of 120 GeV energy at the CERN SP…
Evaluation of a commercial APD array (Avalanche PhotoDiode) for a readout detector in a hadrontherapy beam characterization application
2010
The aim of the present work is the characterization of the S8898–128–02 Avalanche PhotoDiode array (APDs) from Hamamatsu Photonics. This work includes the implementation of a readout system as well as electronic noise estimation in APDs under several conditions varying integration times and clock frequencies.
Production altitude and time delays of the terrestrial gamma flashes: Revisiting the Burst and Transient Source Experiment spectra
2008
[1] On the basis of the RHESSI results it has been suggested that terrestrial gamma flashes (TGFs) are produced at very low altitudes. On the other hand some of the Burst and Transient Source Experiment (BATSE) spectra show unabsorbed fluxes of X rays in the 25–50 keV energy range, indicating a higher production altitude. To investigate this, we have developed a Monte Carlo code for X-ray propagation through the atmosphere. The most important features seen in the modeled spectra are (1) a low-energy cutoff which moves to lower energies as TGFs are produced at higher altitudes, (2) a high-energy cutoff which moves to lower energies as TGFs are observed at larger zenith angles, and (3) time d…
Test and Simulation of a LYSO+APD matrix with a tagged Photon Beam from 40 to 300 MeV
2012
Understanding the energy resolution terms for LYSO based calorimeters with APD readout at low energy (< 500 MeV) is relevant both for the completion of the KLOE-2 experiment, at DAΦNE, and for the design of the Mu2e calorimeter. In this work, we present a dedicated comparison between experimental data, taken in 2011 at the MAMI tagged photon beam facility with a crystal matrix prototype, and a full Geant-4 simulation of this detector. The crystal prototype matrix consisted of 9 2×2 × 15 cm3 LYSO crystals read-out by 10×10 mm2 Hamamatsu avalanche photodiodes (APD) surrounded by 8 PbWO4 crystals read-out by Bialkali photomultipliers for outer leakage recovery granting a total transverse cover…
The backward end-cap for the PANDA electromagnetic calorimeter
2015
The PANDA experiment at the new FAIR facility will cover a broad experimental programme in hadron structure and spectroscopy. As a multipurpose detector, the PANDA spectrometer needs to ensure almost 4π coverage of the scattering solid angle, full and accurate multiple-particle event reconstruction and very good particle identification capabilities. The electromagnetic calorimeter (EMC) will be a key item for many of these aspects. Particle energies ranging from some MeVs to several GeVs have to be measured with a relative resolution of 1% ⊕ 2%/√E/GeV . It will be a homogeneous calorimeter made of PbWO4 crystals and will be operated at -25°C, in order to improve the scintillation light yiel…
Background and muon counting rates in underground muon measurements with a plastic scintillator counter based on a wavelength shifting fibre and a mu…
2010
AbstractIn this short note we present results of background measurements carried out with polystyrene based cast plastic 12.0×12.0×3.0 cm3 size scintillator counter with a wavelength shifting fibre and a multi-pixel Geiger mode avalanche photodiode readout in the Baksan underground laboratory at a depth of 200 metres of water equivalent. The total counting rate of the scintillator counter measured at this depth and at a threshold corresponding to ∼0.37 of a minimum ionizing particle is approximately 1.3 Hz.
Time response of avalanche photodiodes as a function of the internal gain
1998
Abstract Using a red LED and a blue laser as a light source, time response of avalanche photodiodes and Metal-Resistive Silicon (MRS) layer avalanche photodiodes [1] has been measured. A strong dependence of the time resolution on the internal gain has been observed. The obtained results show that the increase of the internal gain improves the time resolution. However, there exists a critical value for the internal gain. Beyond this value a deterioration of the time resolution is observed.
Multi-pixel Geiger-mode avalanche photodiode and wavelength shifting fibre readout of plastic scintillator counters of the EMMA underground experiment
2009
The results of a development of a scintillator counter with wavelength shifting (WLS) fibre and a multi-pixel Geiger-mode avalanche photodiode readout are presented. The photodiode has a metal-resistor-semiconductor layered structure and operates in the limited Geiger mode. The scintillator counter has been developed for the EMMA underground cosmic ray experiment.
Gain stabilization and noise minimization for SiPMs at cryogenic temperatures
2018
Abstract The performance of solid-state photon detectors such as avalanche photodiodes or silicon photomultipliers (SiPMs) is strongly affected by temperature. Important device characteristics for the detection of low light levels or single photons are photon detection efficiency, dark noise, and gain. In the present work the C-series SiPMs from SensL was characterized in cryogenic environments. At 77 K the SiPMs proved to be an excellent choice for single photon detection and an operation point with minimum noise contributions was found. At 4 K the performance was degraded, exhibiting a smaller gain and a larger noise.