Search results for "Values."

showing 10 items of 1353 documents

Peripheral Leptin Levels in Narcoleptic Patients

2007

Narcolepsy is a severe sleep disorder that in most patients is characterized by the deficiency of central orexin. Clinically, narcolepsy is associated with obesity. Currently, there is a literature controversy about the potential alteration of leptin levels in narcoleptic patients. Theoretically, diminished leptin levels could partially contribute to the observed overweight of patients. Two studies have reported decreased leptin levels, whereas a larger, recent study failed to detect differences between patients and controls.To help settle the controversy, we have measured peripheral leptin levels in 42 narcoleptic patients and in 31 body mass index-matched controls.No significant differenc…

AdultLeptinMalemedicine.medical_specialtyEndocrinology Diabetes and Metabolismmacromolecular substancesBody Mass IndexEndocrinologyReference ValuesDiabetes mellitusInternal medicineHumansMedicineAgedNarcolepsySleep disorderbusiness.industryLeptinMiddle Agedmedicine.diseaseObesityPeripheralOrexinMedical Laboratory TechnologyEndocrinologynervous systemFemalebusinessNarcolepsyDiabetes Technology & Therapeutics
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Evaluation of 24-hour gastric acidity in patients with hepatic cirrhosis.

1996

Data from previous studies on gastric acid secretion in patients with hepatic cirrhosis are controversial, due, at least in part, to the possible interference of liver failure and altered gastric mucosal microcirculation on the pharmacological action of the substances used to stimulate the parietal cell. For this reason, we wished to investigate the circadian pattern of gastric acidity by means of continuous 24-hour pH monitoring, which permits measurement of pH fluctuations in a nearly physiological manner and does not require any pharmacological stimulus.Forty-nine patients with liver cirrhosis of different aetiology were recruited for this study. They underwent 24-hour gastric pH-metry w…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosisGastroenterologyGastric AcidReference ValuesInternal medicinemedicineHumansCircadian rhythmProspective StudiesProspective cohort studyAntrumParietal cellAgedHepatologybiologybusiness.industryStomachdigestive oral and skin physiologyHelicobacter pyloriHydrogen-Ion ConcentrationMiddle Agedmedicine.diseasebiology.organism_classificationCircadian Rhythmmedicine.anatomical_structureGastric MucosaGastric acidFemalebusiness
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From being alone to being the only one: Neuroticism is associated with an egocentric shift in an alone context

2019

Objective This research presents evidence for an egocentric shift occurring among individuals high in Neuroticism by the mere thought-and actual state-of being alone. Method Four experiments and one experience sampling study (N = 719). In the experiments, Neuroticism was measured, and participants were randomly primed to adopt either an alone or a "with others" social context mind-set. The experiments measured different expressions of egocentrism. Study 1 measured perspective-taking, Study 2a was focused on social value orientation, Study 2b measured money allocation in a dictator game, and Study 3 measured self-reported and behavioral interpersonal trust. Trust was also the focus of Study …

AdultMale050103 clinical psychologyEgocentrismExperience sampling methodSocial ValuesSocial PsychologyEcological Momentary Assessment050109 social psychologyContext (language use)Interpersonal communicationTrustDictator gameHumans0501 psychology and cognitive sciencesNeuroticismLoneliness05 social sciencesPerspective (graphical)Social environmentMiddle AgedNeuroticismSocial PerceptionEgocentrismFemalePsychologySocial psychologyJournal of Personality
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Assessing Planning Ability Across the Adult Life Span in a Large Population-Representative Sample: Reliability Estimates and Normative Data for the T…

2019

AbstractObjectives:The Tower of London (TOL) test has probably become the most often used task to assess planning ability in clinical and experimental settings. Since its implementation, efforts were made to provide a task version with adequate psychometric properties, but extensive normative data are not publicly available until now. The computerized TOL-Freiburg Version (TOL-F) was developed based on theory-grounded task analyses, and its psychometric adequacy has been repeatedly demonstrated in several studies but often with small and selective samples.Method:In the present study, we now report reliability estimates and normative data for the TOL-F stratified for age, sex, and education …

AdultMale050103 clinical psychologyHuman DevelopmentApplied psychologyNormative dataLarge populationTower of LondonSample (statistics)Neuropsychological TestsGutenberg Health Study (GHS)Task (project management)Cohort StudiesExecutive Function03 medical and health sciences0302 clinical medicineReference ValuesGermanyHumans0501 psychology and cognitive sciencesReliability (statistics)AgedAged 80 and overRegular Researchorganic chemicalsGeneral Neuroscience05 social sciencesReproducibility of ResultsMiddle AgedReliabilityTest (assessment)PlanningPsychiatry and Mental healthClinical PsychologyAdult lifeTOL-FbacteriaNormativeFemaleNeurology (clinical)PsychologyTower030217 neurology & neurosurgeryJournal of the International Neuropsychological Society
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Does angiotensin-converting enzyme gene polymorphism affect blood pressure? Findings after 6 years of follow-up in healthy subjects.

2003

Background: There has been an increase in research into the association between angiotensin-converting enzyme (ACE) gene deletion polymorphism and cardiovascular disease, with conflicting results. The present prospective long-term study was conducted to evaluate whether the DD genotype could also be associated with a higher prevalence of hypertension in healthy subjects, over 6 years of follow-up. Methods: Population: 684 healthy volunteers (aged, 25–55 years): normotensive and free of cardiovascular diseases, with acceptable echocardiographic window. All subjects had to have a normal electrocardiogram (ECG) and echocardiogram (ECHO) at entry. Study protocol: All subjects underwent a comple…

AdultMaleACE-I/D gene polymorphismmedicine.medical_specialtyTime FactorsGenotypePopulationBlood PressurePeptidyl-Dipeptidase AReference ValuesInternal medicineMedicineHumansProspective StudiesFamily historyeducationeducation.field_of_studyPolymorphism Geneticbiologybusiness.industryIncidence (epidemiology)IncidenceAngiotensin-converting enzymeVenous bloodMiddle Agedmedicine.diseaseMutagenesis InsertionalEndocrinologyBlood pressureHeart failureHypertensionbiology.proteinFemaleGene polymorphismCardiology and Cardiovascular MedicinebusinessHealthy subjectGene DeletionFollow-Up StudiesEuropean journal of heart failure
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Virtual endoscopy of the inner ear and the auditory canal.

2000

To assess the role of virtual endoscopy (VE) in the examination of intracisternal structures and of the inner ear, we studied the anatomy of the labyrinth and internal auditory canal using the original CT slices and VE on the unaffected side in three female and three male patients, age range 3–46 years, with contralateral retrocochlear hearing loss. We also examined seven patients with different pathological findings. VE was performed using an advanced postprocessing program with high- resolution 3D data sets of CT (1–1.5 mm thickness, pitch 1.25) and MRI-CISS-3D (constructive interference in steady state) images of the basal cisterns (1.5 T, slice thickness 0.7–1 mm). VE provides an endosc…

AdultMaleAdolescentAuditory canalUser-Computer InterfaceImaging Three-DimensionalInternal auditory meatusReference ValuesmedicineHumansRadiology Nuclear Medicine and imagingInner earVirtual endoscopyChildNeuroradiologymedicine.diagnostic_testbusiness.industryCisternMagnetic resonance imagingEndoscopyAnatomyNeuroma AcousticMiddle AgedCochlear ImplantationEndoscopymedicine.anatomical_structureChild PreschoolEar InnerFemalesense organsNeurology (clinical)Cardiology and Cardiovascular MedicinebusinessNeuroradiology
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Eating-related Intrusive Thoughts Inventory: exploring the dimensionality of eating disorder symptoms.

2011

The aims of this study were, first, to examine the structure and validity of the Eating-related Intrusive Thoughts Inventory (INPIAS), a self-report questionnaire designed to assess eating disorders related to intrusive thoughts (EDITs), and second, to explore the existence of a continuum ranging from normal to abnormal thought intrusions related to eating, weight, and shape. Participants were 574 (408 women) nonclinical community individuals. Analyses revealed that EDITs can be clustered into three sets: appearance-dieting, need to exercise, and thoughts-impulses related to eating disorders. EDITs' consequences showed a two-factor structure: emotional consequences/personal meaning and tho…

AdultMaleAdolescentDiet ReducingPersonality InventoryPsychometricsCompulsive Personality DisorderCultureAnxietyBody weightDevelopmental psychologyFeeding and Eating DisordersThinkingEatingYoung AdultReference ValuesDistractionmedicineBody ImageHumansMeaning (existential)Young adultExerciseGeneral PsychologyDepression (differential diagnoses)DepressionBody WeightReproducibility of ResultsCognitionMiddle Agedmedicine.diseaseEating disordersAnxietyFemalemedicine.symptomPsychologyPsychological reports
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Eyes open and eyes closed as rest conditions: impact on brain activation patterns

2003

The patterns of associated brain activations during eyes-open and eyes-closed states in complete darkness considerably differ in fMRI. An "interoceptive" state with the eyes closed is characterized by visual cortex activation, while an "exteroceptive" state with the eyes open is characterized by ocular motor system activity. The impact of the chosen rest condition (eyes open or eyes closed in complete darkness) on the pattern of brain activations during visual stimulation was evaluated in 14 healthy volunteers. During fixation or dim light room illumination, the activation of the visual cortex was larger with the eyes-open rest condition than with the eyes-closed rest condition; however, ac…

AdultMaleAdolescentEye Movementsgenetic structuresRestCognitive NeuroscienceThalamusSensory systemFixation OcularLateral geniculate nucleusSomatosensory systemReference ValuesImage Interpretation Computer-AssistedmedicineHumansVisual PathwaysDominance CerebralPrefrontal cortexVision OcularVisual CortexBrain MappingBrainGeniculate BodiesAnatomyFrontal eye fieldsImage EnhancementMagnetic Resonance Imagingeye diseasesOxygenVisual cortexmedicine.anatomical_structureNeurologyOculomotor MusclesFixation (visual)Femalesense organsSensory DeprivationArousalPsychologyNeuroscienceNeuroImage
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Correlation of cerebral blood flow and MCA flow velocity measured in healthy volunteers during acetazolamide and CO2 stimulation

1995

Abstract The assessment of the cerebrovascular reserve capacity (RC) has become a widely used tool in the management of cerebrovascular disease. Discrepancies become obvious, however, if results obtained with different methods are compared. Aim of the present study, therefore, was to compare blood velocity and cerebral perfusion data in the same group of healthy test persons. In 32 volunteers regional cerebral blood flow (rCBF) was measured with the 133 Xe-inhalation method. F1 as grey matter flow and the initial slope index (ISI) were computed. Simultaneously flow velocity in the middle cerebral artery (V MCA ) was assessed by transcranial Doppler sonography (TCD). Measurements were perfor…

AdultMaleAdolescentHemodynamicsReference Valuesmedicine.arterymedicineHumansCerebral perfusion pressureAgedResting state fMRIbusiness.industryCarbon DioxideCerebral ArteriesMiddle AgedStimulation ChemicalAcetazolamideNeurologyCerebral blood flowCerebrovascular CirculationAnesthesiaMiddle cerebral arteryFemaleNeurology (clinical)medicine.symptomAcetazolamidebusinessHypercapniaPerfusionBlood Flow Velocitymedicine.drugJournal of the Neurological Sciences
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Momentary Affect Predicts Bodily Movement in Daily Life: An Ambulatory Monitoring Study

2010

There is converging evidence that physical activity influences affective states. It has been found that aerobic exercise programs can significantly diminish negative affect. Moreover, among healthy individuals, moderate levels of physical activity seem to increase energetic arousal and positive affect. However, the predictive utility of affective states for bodily movement has rarely been investigated. In this study, we examined whether momentarily assessed affect is associated with bodily movement in everyday life. Using a previously published data set (Schwerdtfeger, Eberhardt, & Chmitorz, 2008), we reanalyzed 12-hr ecological momentary assessment (EMA) data from 124 healthy volunteer…

AdultMaleAdolescentMovementPhysical activityMonitoring AmbulatoryMotor ActivityAffect (psychology)Developmental psychologyYoung AdultPredictive Value of TestsReference ValuesSurveys and QuestionnairesActivities of Daily LivingHealthy volunteersHumansAerobic exerciseEveryday lifeEnergetic arousalApplied PsychologyAgedMovement (music)Middle AgedAffectComputers HandheldAmbulatoryFemalePsychologyJournal of Sport and Exercise Psychology
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