Search results for "Variation"

showing 10 items of 2124 documents

A few remarks on colloquial language in Italy

2016

The present work focuses on the analysis of colloquial Italian starting from the rasgos coloquializadores (a series of conversational markers) describing the Spanish sociolinguistic research on informal contexts. After a short introduction on the rasgos, the second part of this article deals with the pattern of colloquial Italian. It may be considered a macro-variety sharing features belonging to several varieties of the Italian linguistic repertoire, further supported by the use of dialect. The theoretical context is also based on a significant number of examples from spontaneous and colloquial speech collected in Palermo. These examples show both the varied features of colloquial Italian …

colloquial Italian variation discourse analysis pragmatics code-switching
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Asymptotic behavior of positive solutions of a Dirichlet problem involving supercritical nonlinearities

2013

combined nonlinearitiespositive solutionvariational meth- odSettore MAT/05 - Analisi MatematicaKeywords: elliptic boundary value problemasymptotic behavior
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Functional Assessment of Variants in the TSC1 and TSC2 Genes Identified in Individuals with Tuberous Sclerosis Complex

2011

The effects of missense changes and small in-frame deletions and insertions on protein function are not easy to predict, and the identification of such variants in individuals at risk of a genetic disease can complicate genetic counselling. One option is to perform functional tests to assess whether the variants affect protein function. We have used this strategy to characterize variants identified in the TSC1 and TSC2 genes in individuals with, or suspected of having, Tuberous Sclerosis Complex (TSC). Here we present an overview of our functional studies on 45 TSC1 and 107 TSC2 variants. Using a standardized protocol we classified 16 TSC1 variants and 70 TSC2 variants as pathogenic. In add…

congenital hereditary and neonatal diseases and abnormalitiesGenetic counselingtuberous sclerosis complexBiologyTuberous Sclerosis Complex 1 Protein03 medical and health sciencesTuberous sclerosis0302 clinical medicineTuberous SclerosisGenetic variationTuberous Sclerosis Complex 2 ProteinGeneticsmedicineMissense mutationHumansunclassified variantsGeneGenetics (clinical)Cells Cultured030304 developmental biologyGenetics0303 health sciencesModels GeneticTumor Suppressor ProteinsLife SciencesGenetic Variationmedicine.diseaseTSC23. Good healthnervous system diseasesTSC1medicine.anatomical_structureTSC1TSC2030217 neurology & neurosurgeryCommon disease-common variant
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Psychometric Properties of the “Alcohol Consumption Consequences Evaluation” (ACCE) Scale for Young Spanish University Students

2020

Instruments that evaluate alcohol use consequences among young people do not consider the intensive alcohol consumption pattern that is so characteristic during these ages. Some of these instruments are even ineffective in the Spanish population. Hence the interest in developing an instrument more adapted to the reality of our young people. A total of 601 university students (35.9% male and 64.1% female) from 18 to 20 years old were recruited. All of them answered a total of 77 items obtained from the review of both the scientific literature and the different scales used to measure consequences derived from alcohol consumption. In addition, they completed the AUDIT and the Timeline Followba…

consequenceslcsh:BF1-990Poison controlTest validityLogistic regressionpsychometric properties050105 experimental psychologyStructural equation modeling03 medical and health sciences0302 clinical medicinealcohol drinking patternsPsychology0501 psychology and cognitive sciencestest validityuniversity studentsGeneral PsychologyOriginal ResearchConsumption (economics)05 social sciencesExplained variationExploratory factor analysisConfirmatory factor analysislcsh:PsychologyPsychologyAlcoholPsicometria030217 neurology & neurosurgeryClinical psychologyFrontiers in Psychology
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Event related brain potential (ERP) correlates of activation and effort in state regulation among children with attentional problems

2002

contingent negative variationsuorituspyrkimysmotivaatiohäiriötcontinuous performance taskCNVCPTsäätelyP300tilatarkkaavaisuus
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Convex analysis and dual problems

2018

Tässä tutkielmassa tarkastellaan valittujen variaatiolaskennan ongelmien ja näiden duaaliongelmien välisiä suhteita. Tutkielmassa esitetään aiheen yleinen teoria ja annetaan esimerkkejä sovelluksista.

convex analysiscalculus of variations
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SULT1A1 gene deletion in BRCA2-associated male breast cancer: a link between genes and environmental exposures?

2013

SULT1A1, a member of sulfotransferase superfamily, is a drug and hormone metabolizing enzyme involved in the metabolism of a variety of potential mammary carcinogens of endogenous and exogenous origin. Interestingly, the metabolic activity of SULT1A1 can be affected by varia- tions in gene copy number. Male Breast Cancer (MBC) is a rare disease and less investigated disease compared to female BC (FBC). As in FBC, the concurrent effects of genetic risk factors, particularly BRCA2 mutations, increased exposure to estrogens and environmental carcinogens play a relevant role in MBC. By quantitative real-time PCR with TaqMan probes, we investigated the presence of SULT1A1 gene copy number variat…

copy number variations (CNVs)MaleSettore MED/06 - Oncologia MedicaShort Communicationmale breast cancerDiseaseBiologyBreast Neoplasms Malecopy number variations (cnvs); brca2; sult1a1; male breast cancerPathogenesisSULT1A1 GeneSULT1A1 copy number variations (CNVs) BRCA2 male breast cancermedicineHumansGenetic Predisposition to DiseaseCopy-number variationskin and connective tissue diseasesGeneCarcinogenBRCA2 ProteinGeneticsEnvironmental ExposureCell BiologyEnvironmental exposuremedicine.diseaseBRCA2ArylsulfotransferaseMale breast cancerSULT1A1Molecular MedicineFemaleGene Deletion
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Speciality or specialty? : A case study on British American variation

2009

 Brittiläisen ja amerikkalaisen englannin eroja pyritään usein havainnollistamaan yksioikoisilla vastakkainasetteluilla ja erityisesti kaikille tutuilla esimerkkitapauksilla, kuten autumn ja fall tai colour ja color. Tällaiset listat esittävät eri varieteetit ja niiden ominaisuudet toisensa poissulkevina, oli kyse sitten leksikaalisesta tai vaikkapa ortografisesta erosta. Nykymaailmassa eri kielimuodot ovat kuitenkin väistämättä yhteyksissä toisiinsa tavalla tai toisella, eikä kielellisiä piirteitä kenties kannata enää erotella näin simplistisesti vain joko brittiläisiin tai amerikkalaisiin. Tutkin kandidaatintyössäni lähisynonyymisiä sanoja speciality ja specialty, jotka tavataan mieltää e…

corpus linguisticsvariationAmericanisationdistribution
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Adaptation to a seasonally varying environment: a strong latitudinal cline in reproductive diapause combined with high gene flow in Drosophila montana

2011

Adaptation to seasonal changes in the northern hemisphere includes an ability to predict the forthcoming cold season from gradual changes in environmental cues early enough to prepare for the harsh winter conditions. The magnitude and speed of changes in these cues vary between the latitudes, which induces strong selection pressures for local adaptation. We studied adaptation to seasonal changes in Drosophila montana, a northern maltfly, by defining the photoperiodic conditions leading to adult reproductive diapause along a latitudinal cline in Finland and by measuring genetic differentiation and the amount of gene flow between the sampling sites with microsatellites. Our data revealed a cl…

critical day lengthgenetic variationpopulation structuregene flowmicrosatellitesseasonal adaptation
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Existence of three solutions for a mixed boundary value system with (p_1,...,p_m)-Laplacian

2014

In this paper we prove the existence of at least three weak solutions for a mixed boundary value system with (p_1,,...,p_m)-Laplacian. The approach is based on variational methods.

critical points variational methods p-LaplacianSettore MAT/05 - Analisi Matematica
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