Search results for "Vector"

Exact frequency response of bars with multiple dampers

2016

The paper addresses the frequency analysis of bars with an arbitrary number of dampers, subjected to harmonically varying loads. Multiple external/internal dampers occurring at the same position along the bar, modelling external damping devices and internal damping due to damage or imperfect connections, are considered. In this context, the challenge is to handle simultaneous discontinuities of the response variables, i.e. axial force/displacement discontinuities at the location of external/internal dampers. Based on the theory of generalized functions, the paper will present exact closed-form expressions of the frequency response under point/polynomial loads, which hold regardless of the n…

Time-resolved buildup of twisted indirect exchange interaction in two-dimensional systems

2019

We study theoretically the time-domain dynamics of the spin-dependent Ruderman-Kittel-Kasuya-Yosida (RKKY) interaction between driven magnetic impurities localized in a spin-orbit-coupled two-dimensional system. Particular attention is given to the influence of the spin-orbit coupling (SOC) on the system's dynamical response to a time-dependent precessional motion of the localized magnetic moment. We show that, via the RKKY mechanism, a flip of the spin $z$ component of one localized moment affects all $x,\phantom{\rule{4pt}{0ex}}y$, and $z$ spin components of the other localized moment. The Friedel oscillations and the transient spin current triggered by the time-varying localized spin dep…

Partitions of finite vector spaces: An application of the frobenius number in geometry

1978

A genetic integrated fuzzy classifier

2005

This paper introduces a new classifier, that is based on fuzzy-integration schemes controlled by a genetic optimisation procedure. Two different types of integration are proposed here, and are validated by experiments on real data sets of biological cells. The performance of our classifier is tested against a feed-forward neural network and a Support Vector Machine. Results show the good performance and robustness of the integrated classifier strategies.

Binding and/or hydrolysis of purine‐based nucleotides is not required for IM30 ring formation

2021

IM30, the inner membrane-associated protein of 30 kDa, is conserved in cyanobacteria and chloroplasts. Although its exact physiological function is still mysterious, IM30 is clearly essential for thylakoid membrane biogenesis and/or dynamics. Recently, a cryptic IM30 GTPase activity has been reported, albeit thus far no physiological function has been attributed to this. Yet, it is still possible that GTP binding/hydrolysis affects formation of the prototypical large homo-oligomeric IM30 ring and rod structures. Here, we show that the Synechocystis sp. PCC 6803 IM30 protein in fact is an NTPase that hydrolyzes GTP and ATP, but not CTP or UTP, with about identical rates. While IM30 forms lar…

RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy

2014

Macroautophagy is a degradative pathway that sequesters and transports cytosolic cargo in autophagosomes to lysosomes, and its deterioration affects intracellular proteostasis. Membrane dynamics accompanying autophagy are mostly elusive and depend on trafficking processes. RAB GTPase activating proteins (RABGAPs) are important factors for the coordination of cellular vesicle transport systems, and several TBC (TRE2-BUB2-CDC16) domain-containing RABGAPs are associated with autophagy. Employing C. elegans and human primary fibroblasts, we show that RAB3GAP1 and RAB3GAP2, which are components of the TBC domain-free RAB3GAP complex, influence protein aggregation and affect autophagy at basal an…

No-Reference 3D Mesh Quality Assessment Based on Dihedral Angles Model and Support Vector Regression

2016

International audience; 3D meshes are subject to various visual distortions during their transmission and geometrical processing. Several works have tried to evaluate the visual quality using either full reference or reduced reference approaches. However, these approaches require the presence of the reference mesh which is not available in such practical situations. In this paper, the main contribution lies in the design of a computational method to automatically predict the perceived mesh quality without reference and without knowing beforehand the distortion type. Following the no-reference (NR) quality assessment principle, the proposed method focuses only on the distorted mesh. Specific…

Gamma-convergence of Gaussian fractional perimeter

2021

Abstract We prove the Γ-convergence of the renormalised Gaussian fractional s-perimeter to the Gaussian perimeter as s → 1 - {s\to 1^{-}} . Our definition of fractional perimeter comes from that of the fractional powers of Ornstein–Uhlenbeck operator given via Bochner subordination formula. As a typical feature of the Gaussian setting, the constant appearing in front of the Γ-limit does not depend on the dimension.

Identification of SCP2165, a new SCP2-derived plasmid of Streptomyces coelicolor A3(2).

2005

Aims:  Characterization of SCP2165, a plasmid identified in the Gram-positive bacterium Streptomyces coelicolor A3(2). Methods and Results:  Pulsed-field gel electrophoresis (PFGE) of mycelia of a S. coelicolor strain embedded in low melting agarose revealed the presence of a plasmid. Restriction enzyme mapping and sequence analysis of a 2·1 kb fragment revealed that this plasmid could be SCP2. SCP2 and its spontaneous derivative SCP2* are self-transmissible plasmids and have chromosome mobilizing ability (c.m.a.). SCP2* has a c. 1000-fold increased c.m.a. compared with SCP2. Interestingly the plasmid, named SCP2165, shows a c.m.a. from 5 × 10−2 to 1 × 10−1 which is 50–100-fold higher than …

p53 Gene Therapy

2002

Based on the frequent inactivation of the p53 gene product in human malignancy, and its functional involvement in tumor suppression, cell cycle control and apoptosis, p53 was identified as an attractive target for somatic gene therapy strategies in cancer. Several pilot and phase I studies explored the intratumoral injection of viral expression vectors encoding the p53 cDNA in patients with advanced cancer. These studies confirmed the safety and feasibility of this approach. Further, vector-specific transgene expression and surrogate markers for biological activity of the transgene were demonstrated. Local tumor regression, or stabilization of tumor growth, were observed in some studies, an…