Search results for "Veins"

showing 10 items of 260 documents

Oxidative stress induces myeloperoxidase expression in endocardial endothelial cells from patients with chronic heart failure.

2009

Increased oxidative stress has been implicated in the pathogenesis of a number of cardiovascular diseases. Recent findings suggest that myeloperoxidase (MPO) may play a key role in the initiation and maintenance of chronic heart failure (CHF) by contributing to the depletion of the intracellular reservoir of nitric oxide (NO). NO consumption through MPO activity may lead to protein chlorination or nitration, leading to tissue damage. Primary cultures of human endocardial endothelial cells (EEC) obtained at heart transplantation of patients with CHF and human umbilical vein endothelial cells (HUVEC) were subjected to oxidative stress by incubation with hydrogen peroxide at non lethal (60 mic…

medicine.medical_specialtyPathologyUmbilical VeinsEndothelium3-chlorotyrosine endocardium endothelial cells myeloperoxidase oxidative stressPhysiologyGene Expressionmedicine.disease_causeUmbilical veinNitric oxidechemistry.chemical_compoundPhysiology (medical)Internal medicinemedicineHumansRNA MessengerCells Cultured3-ChlorotyrosinePeroxidaseHeart FailurebiologyReverse Transcriptase Polymerase Chain ReactionSettore BIO/16 - Anatomia UmanaNitrotyrosineMyocardiumEndothelial CellsHydrogen PeroxideOxidantsImmunohistochemistryEndothelial stem cellOxidative Stressmedicine.anatomical_structureEndocrinologychemistryMyeloperoxidaseChronic Diseasebiology.proteinTyrosineCardiology and Cardiovascular MedicineOxidative stress
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Muscarinic mobilization of choline in rat brain in vivo as shown by the cerebral arterio-venous difference of choline.

1987

In anesthetized rats, the choline levels of cerebrospinal fluid and plasma obtained from blood collected from peripheral vessels (carotid artery, cardiac vessels) and from the transverse sinus were determined with a radioenzymatic assay. Cortical release of choline was studied using the "cup technique." The plasma choline level of the peripheral blood (11.5 mumol/L) was lower than that of the sinus blood. The resulting cerebral arterio-venous difference of choline was negative (3.2 mumol/L) and reflected the net release of choline from the whole brain. The plasma choline levels were not different irrespective of whether the rats were anesthetized with ether, urethane, or pentobarbital. Howe…

medicine.medical_specialtyPentobarbitalAgingBiochemistryCholineVeinsCellular and Molecular Neurosciencechemistry.chemical_compoundCerebrospinal fluidIn vivoInternal medicineMuscarineBlood plasmaMuscarinic acetylcholine receptormedicineOxotremorineCholineAnimalsOsmolar ConcentrationBrainVenous PlasmaArteriesDietRatsEndocrinologychemistryCerebrovascular Circulationmedicine.drugJournal of neurochemistry
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Assessment of pulmonary hypertension by CT and MR imaging.

2003

In the recent World Health Organization (WHO) classification the group of pulmonary arterial hypertension (PH) comprises the classic primary pulmonary hypertension and several conditions with definite or very high risk factors to develop pulmonary arterial hypertension. Therapeutic advances drive the need for a comprehensive pre-therapeutic evaluation for optimal treatment. Furthermore, follow-up examinations need to be performed to monitor changes in disease status and response to therapy. Up to now, the diagnostic imaging work-up of PH comprises mainly echocardiography, invasive right heart catheterization and ventilation/perfusion scintigraphy. Due to technical advances helical computed …

medicine.medical_specialtyPulmonary CirculationHeart DiseasesHypertension PulmonaryPulmonary ArteryScintigraphyInternal medicineMedical imagingmedicineHumansRadiology Nuclear Medicine and imagingLungNeuroradiologymedicine.diagnostic_testbusiness.industryMagnetic resonance imagingInterventional radiologyGeneral Medicinemedicine.diseasePulmonary hypertensionMagnetic Resonance ImagingPulmonary VeinsAngiographyCardiologyRadiologyDifferential diagnosisbusinessTomography X-Ray ComputedEuropean radiology
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Kinin receptors in human vascular tissue: their role in atheromatous disease

1997

Using samples of many human blood vessels, obtained at autopsy and specific antibodies directed to peptide sequences of the kinin B1 and B2 receptors, we demonstrate the localisation of these receptors within the human vascular system using standard immunolabelling techniques. In large elastic arteries and veins, kinin receptors are present only in the endothelial cells whereas in all muscular arteries and arterioles, these receptors are present in both the endothelial and smooth muscle cells. The identification of kinin receptors in human blood vessels confirms that kinins may modulate both vascular permeability and contractility. The incidental finding at histology, of patchy atheromatous…

medicine.medical_specialtyReceptor Bradykinin B2EndotheliumArteriosclerosisMolecular Sequence DataImmunocytochemistryEnzyme-Linked Immunosorbent AssayVascular permeabilityBiologyReceptor Bradykinin B1Muscle Smooth VascularVeinsCapillary PermeabilityContractilityAntibody SpecificityInternal medicinemedicineHumansVasoconstrictor AgentsAmino Acid SequenceReceptorVascular tissuePharmacologyStaining and LabelingReceptors BradykininArteriesKininImmunohistochemistryMolecular WeightArteriolesmedicine.anatomical_structureEndocrinologycardiovascular systemImmunohistochemistryKallikreinsAutopsyEndothelium VascularTissue KallikreinsMuscle ContractionImmunopharmacology
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Tangential Venous Resections during Robotic-Assisted Pancreaticoduodenectomy: the Results of a Case Series (with Video)

2020

Introduction: Despite the potential advantages in terms of microdissection and microsuturing capabilites, the robotic approach for borderline resectable pancreatic cancer is scarcely reported. Methods: We report our technique for a robotic-assisted pancreaticoduodenectomy with tangential Portal/ Superior Mesenteric Vein resection/reconstruction (RPD PV/SMV).We also compared the surgical outcomes of eight consecutive patients undergoing RPD PV/SMV with that of sixty patients who underwent robotic-assisted pancreaticoduodenectomy (RPD) in the same period of time. Results: A total of eight consecutive patients underwent RPD PV/SMV. We observed an increased estimated blood loss (550 vs 280 mL, …

medicine.medical_specialtyRobotic assistedmedicine.medical_treatmentPancreaticoduodenectomyResection03 medical and health sciencesMesenteric VeinsPancreatectomy0302 clinical medicineRobotic Surgical ProceduresBlood lossBorderline resectablemedicineHumansSuperior mesenteric veinRetrospective StudiesPortal Veinbusiness.industryGastroenterologyPancreaticoduodenectomyVascular resectionSurgeryPancreatic NeoplasmsVideo techniqueTreatment Outcome030220 oncology & carcinogenesisOperative time030211 gastroenterology & hepatologySurgeryRobotic-assisted pancreaticoduodenectomybusinessHospital stay
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Video-assisted two-stage basilic vein transposition for creation of brachio-basilic arteriovenous fistulae

2012

We report our experience in a mixed minimally-in- vasive technique for the two-stage transposition of basilic vein on a small series of eight patients. The operative tech- nique consisted of a modified endoscopic (1) approach for the two-stage transposition (2). The intervention was performed under Brachial Plexus Block (3).

medicine.medical_specialtyTime FactorsBasilic VeinTreatment outcomeOperative TimeArteriovenous fistula; End Stage Renal Disease; Video-assisted surgeryVideo-assisted surgerySettore MED/22 - Chirurgia VascolareSurgical methodsVeinsTransposition (music)Upper ExtremityArteriovenous Shunt SurgicalRenal DialysismedicineHumansVideo assistedVascular PatencyArteriovenous fistulabusiness.industryEndoscopyBrachial Plexus BlockSurgerySettore MED/18 - Chirurgia GeneraleTreatment OutcomeSurgery Computer-AssistedNephrologyOperative timeSurgeryEnd Stage Renal Diseasebusiness
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The use of a new kind of low profile retractor for arteriovenous fistula procedure simplifies and speeds up the intervention

2009

Purpose The aim of this study was to demonstrate the effectiveness of a new kind of disposable surgical retractor in arteriovenous fistula (AVF) procedures in order to achieve an easier, faster and safer surgical intervention. Methods Between January and June 2008, 22 AVF procedures were performed using the 3PAWS ReeTrakttrade; (Insightra Inc. - Irvine, Ca., USA) a self-retaining, low profile retractor. An equivalent patient sample, in which an AVF was performed using conventional retraction devices, was considered for comparison of the intra- and post-operative results. Results In all of the 22 AVF procedures performed, the ReeTrakt™ system has simplified the performance of the surgical te…

medicine.medical_specialtyTime Factorsmedicine.medical_treatment030232 urology & nephrologyArteriovenous fistulaarterioveunous fistula retractors030204 cardiovascular system & hematology03 medical and health sciencesArteriovenous Shunt Surgical0302 clinical medicineOperating timeHumansMedicinePatient groupDisposable EquipmentReduction (orthopedic surgery)Brachiocephalic VeinsRetrospective StudiesSurgical teamSurgical instrumentationSurgical Fixation Devicebusiness.industryEquipment DesignSurgical Instrumentsmedicine.diseasearteriovenous fistulaReeTrakt systemSurgeryRetractorForearmSettore MED/18 - Chirurgia GeneraleTreatment OutcomeNephrologyRadial ArterySurgerybusiness
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Prospective evaluation of parathyroid graft function after total parathyroidectomy and heterotopic autotransplantation in renal hyperparathyroidism b…

1998

The value of gradients for intact parathyroid hormone (PTH) in the assessment of graft function after total parathyroidectomy/autotransplantation for renal hyperparathyroidism was evaluated in a prospective follow-up study. Altogether 99 patients who underwent operation from August 1, 1987 to December 31, 1996 were prospectively investigated and reexamined postoperatively, including analyses of serum calcium, alkaline phosphatase, and intact PTH in the antecubital venous blood of both arms. The postoperative course is known for all patients. Of the 99 patients included in the study, 95 underwent one to nine reexaminations (median three) over follow-up periods of 1 month to 5 years (median 2…

medicine.medical_specialtyTransplantation Heterotopicmedicine.medical_treatmentParathyroid hormoneTransplantation AutologousVeinsParathyroid GlandsmedicineHumansProspective StudiesParathyroidectomybusiness.industryMediastinumVenous bloodAutotransplantationSurgeryCardiac surgeryForearmmedicine.anatomical_structureCardiothoracic surgeryParathyroid HormoneSurgeryCalciumHyperparathyroidism SecondaryKidney Diseasesbusinesshormones hormone substitutes and hormone antagonistsAbdominal surgeryHormoneWorld journal of surgery
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The European Multicenter Study on Cyanoacrylate Embolization of Refluxing Great Saphenous Veins without Tumescent Anesthesia and without Compression …

2016

medicine.medical_specialtyTumescent anesthesiabusiness.industrymedicine.medical_treatmentCompression therapySurgerylaw.inventionMulticenter studyCyanoacrylatelawAnesthesiamedicineSurgeryEmbolizationCardiology and Cardiovascular MedicinebusinessSaphenous veinsJournal of vascular surgery. Venous and lymphatic disorders
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Progestogens reduce thromboxane production by cultured human endothelial cells.

2011

Objectives Progestogens have been poorly studied concerning their roles in endothelial physiology. Prostanoids are vasoactive compounds, such as thromboxane A2, a potent vasoconstrictor, and prostacyclin, a vasodilator. We examined the effects of two progestogens used clinically, progesterone and medroxyprogesterone acetate, on thromboxane A2 production by cultured human umbilical vein endothelial cells (HUVEC) and investigated the role of progesterone receptors and the enzymes involved in production of thromboxane A2 and prostacyclin. Methods Cells were exposed to 1‐100 nmol/l of either progesterone or medroxyprogesterone acetate, and thromboxane A2 production was measured in culture mediu…

medicine.medical_specialtyUmbilical VeinsAntineoplastic Agents HormonalThromboxaneBlotting WesternGene ExpressionProstacyclinMedroxyprogesterone AcetatePolymerase Chain ReactionProstacyclin synthaseThromboxane receptorThromboxane ProductionThromboxane A2chemistry.chemical_compoundThromboxane A2Hormone AntagonistsCytochrome P-450 Enzyme SystemInternal medicineProgesterone receptorMedicineHumansCyclooxygenase InhibitorsRNA MessengerCells CulturedProgesteronebiologyDose-Response Relationship Drugbusiness.industryObstetrics and GynecologyEndothelial CellsGeneral MedicineIntramolecular OxidoreductasesThromboxane B2MifepristoneEndocrinologychemistrycardiovascular systembiology.proteinPyrazolesThromboxane-A synthaseThromboxane-A SynthaseProgestinsbusinessmedicine.drugClimacteric : the journal of the International Menopause Society
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