Search results for "Vertebrae"

showing 10 items of 180 documents

Scheie syndrome: enzyme replacement therapy does not prevent progression of cervical myelopathy due to spinal cord compression.

2009

Hurler-Scheie syndrome is caused by alpha-l-iduronidase deficiency. Enzyme replacement therapy (ERT) can improve physical capacity and reduces organomegaly. However, the effect on bradytrophic connective tissue is limited. As intravenously administered enzyme cannot cross the blood-brain barrier, the therapy of choice for the more severe Hurler syndrome is haematopoietic stem cell transplantation (HCT). In the more attenuated Scheie syndrome, neurological impairment is less severe; therefore, ERT may be appropriate to treat these patients. Information on long-term outcome in Scheie patients undergoing ERT is scarce. We report a 38-year-old female Scheie patient who has been on ERT for 8 yea…

Adultcongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyMucopolysaccharidosis IMyelopathyIduronidaseSpinal cord compressionMucopolysaccharidosis IGeneticsmedicineHumansEnzyme Replacement TherapyHurler syndromeGenetics (clinical)business.industryHematopoietic Stem Cell Transplantationnutritional and metabolic diseasesBrainEnzyme replacement therapymedicine.diseaseSpinal cordSurgeryTransplantationmedicine.anatomical_structureCervical VertebraeDisease ProgressionFemaleScheie syndromebusinessSpinal Cord CompressionJournal of inherited metabolic disease
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Anterior fusion for cervical spondylosis

1978

Anterior fusion was performed on 138 patients as treatment for degenerative changes of the cervical vertebral column. The results were checked after up to 11 years in 122 patients and were found to be good in 55%, fair in 3895% and poor in 6.5%. There were complications of phonetic paralysis in one case, Horner syndrome in two cases, 2 wound infections, and complaints about the iliac crest in 3 patients. Kyphosis at the fused segment occurred 26.1% of cases, the average angle being 15.3 degrees, but it did not influence the clinical results. Mortality was 2%. Inadequate visualization of the nerve roots at operation was probably the reason for the segmental deficits and suggestions were made…

Adultmedicine.medical_specialtyNerve rootKyphosisHorner syndromeTransplantation AutologousIliac crestMyelopathyPostoperative ComplicationsParalysismedicineCervical spondylosisHumansKyphosisOsteochondritisAgedNeuroradiologyBone Transplantationbusiness.industryMiddle Agedmedicine.diseaseSurgerySpinal Fusionmedicine.anatomical_structureNeurologyCervical VertebraeSpinal DiseasesNeurology (clinical)medicine.symptombusinessJournal of Neurology
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Intermittent intramuscular clodronate therapy: a valuable option for older osteoporotic women

2005

Agingmedicine.medical_specialtyOsteoporosisTreatment outcomeMEDLINE.Injections IntramuscularDrug Administration Schedulelaw.inventionPhysical medicine and rehabilitationPharmacotherapyRandomized controlled triallawBone DensitymedicineHumansFemurVitamin DOsteoporosis PostmenopausalAgedPain MeasurementLumbar Vertebraecalcium clodronic acid vitamin DBone Density Conservation Agentsbusiness.industryGeneral Medicinemedicine.diseaseTreatment OutcomeBack PainPhysical therapyCalciumDrug Therapy CombinationFemaleGeriatrics and GerontologyClodronic Acidbusiness
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The Smith-Robinson Approach to the Subaxial Cervical Spine: A Stepwise Microsurgical Technique Using Volumetric Models From Anatomic Dissections.

2020

BACKGROUND: The Smith-Robinson1 approach (SRA) is the most widely used route to access the anterior cervical spine. Although several authors have described this approach, there is a lack of the stepwise anatomic description of this operative technique. With the advent of new technologies in neuroanatomy education, such as volumetric models (VMs), the understanding of the spatial relation of the different neurovascular structures can be simplified. OBJECTIVE: To describe the anatomy of the SRA through the creation of VMs of anatomic dissections. METHODS: A total of 4 postmortem heads and a cervical replica were used to perform and record the SRA approach to the C4-C5 level. The most relevant…

Anterior cervical approachAnterior cervical approach Anterior neck Cervical spine Smith-Robinson approach Surgical anatomy Volumetric modelsmedicine.medical_treatmentSurgical planningNOSmith-Robinson approach03 medical and health sciences0302 clinical medicineSurgical anatomyVolumetric modelsCervical spinePlatysma musclemedicineHumans030212 general & internal medicineAnterior neckAnterior neckbusiness.industryDissectionSurgical anatomyAnatomyMicrosurgeryNeurovascular bundleCervical spineDissectionCervical VertebraeNeck DissectionSurgeryNeurology (clinical)business030217 neurology & neurosurgeryNeckDiskectomyOperative neurosurgery (Hagerstown, Md.)
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Inter-and intra-tester reliability of a battery of cervical movement control dysfunction tests

2015

Abstract Background Apart from the cranio-cervical flexion test and the deep neck flexor endurance test, evidence related to reliability of cervical movement control dysfunction tests is lacking. Objectives This study investigated the inter- and intra-tester reliability of a battery of cervical movement control dysfunction tests and the effect of clinician experience on reliability in 15 patients with chronic neck pain and 17 non-neck pain controls. In addition, it explored whether impaired performance on this battery of tests was more frequently observed in the neck pain group. Design Inter and intra-tester reliability study. Method Participants were videotaped while performing a battery o…

Battery (electricity)AdultMalemedicine.medical_specialtyFlexion TestPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationNeck MusclesmedicineHumansPhysical endurancePain Measurement/methodsReliability (statistics)Movement controlPain Measurement030222 orthopedicsNeck painNeck Painbusiness.industryNeck Pain/diagnosisGeneral Medicinecervical vertebraeConfidence intervalTest (assessment)medicine.anatomical_structurePhysical therapyFemaleNeck Muscles/physiopathologyreproducibility of resultsmedicine.symptombusiness030217 neurology & neurosurgeryCervical vertebrae
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Quantitative ultrasound predicts bone mineral density and failure load in human lumbar vertebrae

2006

Quantitative ultrasound is in widespread clinical use for assessment of bone quality at peripheral skeletal sites, but has not yet been applied to those sites in the axial skeleton, such as the spine and hip, where osteoporotic fractures are common.Ultrasound measurements were made in 11 cadaveric vertebrae and relationships with bone mineral density and failure load were investigated. An ultrasonic imaging system was used to measure speed of sound, broadband ultrasonic attenuation, and attenuation at a single frequency, through the vertebral body in the sagittal plane. Ultrasonic measurements were averaged over a region of interest centrally within the vertebral body, and were calculated w…

Bone mineralLumbar VertebraeAxial skeletonMaterials scienceBone densitybusiness.industryOsteoporosisUltrasoundBiophysicsLumbar vertebraeAnatomymedicine.diseaseBone and BonesVertebramedicine.anatomical_structureBone DensitymedicineHumansOrthopedics and Sports MedicineUltrasonic sensorbusinessUltrasonographyBiomedical engineeringClinical Biomechanics
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Prevalence of carotid artery calcifications among 2,500 digital panoramic radiographs of an adult Brazilian population

2018

Background The aim of the present study was to analyze the epidemiological data of digital panoramic radiographs revealing suggestive images of carotid artery calcifications (CAC) from a Northeast Brazilian population. Material and Methods A cross-sectional retrospective study was conducted with 2,500 digital panoramic radiographs obtained from a single imaging reference center in Northeast Brazil. Images from individuals of both sexes and older than 18 years were included and those that did not cover the region of cervical vertebrae or presented low radiographic quality were excluded. Data were analyzed regarding prevalence, location (bilateral, right or left), sex, and age using the Chi-s…

Carotid Artery DiseasesMalemedicine.medical_specialtyCross-sectional studyCarotid arteriesRadiography030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineStatistical significanceRadiography PanoramicEpidemiologyPrevalencemedicineHumansVascular CalcificationGeneral DentistryAgedRetrospective StudiesOral Medicine and Pathologybusiness.industryResearchRetrospective cohort study030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Cross-Sectional Studiesmedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASFemaleSurgeryBrazilian populationRadiologybusinessBrazilCervical vertebrae
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A fatal iatrogenic right vertebral injury after transoral odontoidectomy and posterior cervical stabilization for a type II odontoid fracture.

2014

Abstract The authors present a singular case of an iatrogenic right vertebral artery injury, involving a 67 year-old man, who reported a type II odontoid fracture (Anderson and D'Alonzo Classification) and posterior atlantoaxial dislocation following a road traffic accident. A small injury involving the right vertebral artery occurred as a consequence of transoral odontoidectomy and posterior cervical stabilization. It was caused by bone spicules of spinal origin and their presence was confirmed by the histological section of the right vertebral artery at the level of C1–C2. The case confirms how iatrogenic vertebral artery injuries during cervical spine surgery may be potentially lethal, e…

Cervical spine surgeryMalemedicine.medical_specialtyVertebral arteryIatrogenic DiseaseJoint DislocationsArterial Occlusive DiseasesOdontoid fracturePathology and Forensic MedicineFatal OutcomeSettore MED/43 - Medicina Legalemedicine.arteryOdontoid ProcessingleseRight vertebral arteryMedicineHumansSingular caseVertebral ArteryOdontoid fractureAgedbusiness.industryAtlantoaxial dislocationTransoral odontoidectomyAccidents TrafficOsteonecrosisVertebral injuryThrombosisGeneral MedicineDecompression SurgicalSurgeryRoad traffic accidentAtlanto-Axial JointVertebral artery injuryCerebrovascular CirculationHypoxia-Ischemia BrainCervical VertebraeSpinal FracturesRadiologybusinessLawJournal of forensic and legal medicine
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Regional and experiential differences in surgeon preference for the treatment of cervical facet injuries: a case study survey with the AO Spine Cervi…

2021

Abstract Purpose The management of cervical facet dislocation injuries remains controversial. The main purpose of this investigation was to identify whether a surgeon’s geographic location or years in practice influences their preferred management of traumatic cervical facet dislocation injuries. Methods A survey was sent to 272 AO Spine members across all geographic regions and with a variety of practice experience. The survey included clinical case scenarios of cervical facet dislocation injuries and asked responders to select preferences among various diagnostic and management options. Results A total of 189 complete responses were received. Over 50% of responding surgeons in each region…

Cervical spine; Joint dislocations; Neck injuries; Spinal diseases; Spinal injuries; Traumamedicine.medical_specialtyFacet (geometry)Neck injurieNeuroscience(all)610 Medicine & healthExperiential learningTraumaJoint dislocation03 medical and health sciencesJoint dislocations0302 clinical medicineCervical spineSpinal diseasemedicineHumansOrthopedics and Sports Medicine030212 general & internal medicineJoint dislocation610 Medicine & healthCervical spine ; Joint dislocations ; Neck injuries ; Spinal diseases ; Spinal injuries ; TraumaSurgeonsValidation groupSpinal injuriebusiness.industrySpine.cervicalmedicine.diseasePreferenceNeck injuriesSpinal injuriesSpinal FusionCervical VertebraePhysical therapySurgeryNeurosurgeryAnterior approachbusiness030217 neurology & neurosurgerySpinal diseases
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A comparative study of mechanical properties of fresh and frozen-thawed porcine intervertebral discs in a bioreactor environment

2016

Abstract Limited availability of fresh intervertebral discs (IVDs) necessitates the use of frozen-thawed samples in biomechanical investigations. Several authors have reported the mechanical properties of frozen-thawed IVDs, but few studies have investigated the effects of storage temperature and cooling rate. The validity and reliability of the applied freezing-thawing procedures are still relatively unknown. The study aims to compare the mechanical responses of fresh porcine IVDs and porcine IVDs, which were frozen at different freezing temperatures with a controlled-rate cooling process and then thawed. The specimens were obtained from pigs aged 6 months. A total of 18 functional spine u…

Cryopreservationmusculoskeletal diseasesLumbar VertebraeMaterials scienceSwine0206 medical engineeringBiomedical EngineeringReproducibility of Results02 engineering and technologymusculoskeletal system020601 biomedical engineeringBiomechanical PhenomenaBiomaterials03 medical and health sciencesBioreactors0302 clinical medicineCooling rateMechanics of MaterialsFreezingBioreactorAnimalsFrozen storageIntervertebral Disc030217 neurology & neurosurgeryBiomedical engineeringJournal of the Mechanical Behavior of Biomedical Materials
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