Search results for "Vial"

Treatment of soft tissue sarcoma in childhood and adolescence: A report of the german cooperative soft tissue sarcoma study

1992

Background In the first German soft tissue sarcoma (STS) study, CWS-81, 344 patients younger than 19 years of age who had previously untreated soft tissue sarcoma were studied. For this analysis, there were 218 patients with chemosensitive STS (Group A: rhabdomyosarcoma [RMS], synovial sarcoma, extraosseous Ewing sarcoma, leiomyosarcoma, undifferentiated sarcoma, and malignant peripheral neuroectodermal tumor) who could be studied for a minimum potential follow-up time of 6 years. Methods A staging system based on the postoperative extent of the disease was used. The chemotherapy for Stage I-III disease consisted of vincristine, dactinomycin, cyclophosphamide, and doxorubicin (VACA). Patien…

Ultrasound-Guided Periprosthetic Biopsy in Failed Total Hip Arthroplasty: A Novel Approach to Test Infection in Patients With Dry Joints

2021

Background: To diagnose periprosthetic joint infection (PJI) preoperatively, ultrasound-guided joint aspiration (US-JA) may not be performed when effusion is minimal or absent. We aimed to report and investigate the diagnostic performance of ultrasound-guided periprosthetic biopsy (US-PB) of synovial tissue to obtain joint samples in patients without fluid around the implants. Methods: One-hundred nine patients (55 men; mean age: 68 ± 13 years) with failed total hip arthroplasty (THA) who underwent revision surgery performed preoperative US-JA or US-PB to rule out PJI. Results: Sixty-nine of 109 patients had joint effusion and underwent US-JA, while the remaining 40 with dry joint re…

Potential Use of a Diluted High-relaxivity Gadolinium-based Intra-articular Contrast Agent for Magnetic Resonance Arthrography: An In-vitro Study

2019

Abstract Background Magnetic resonance arthrography (MRA) requires intra-articular injection of gadolinium-based diluted paramagnetic contrast material. To our knowledge, gadobenate dimeglumine (Gd-BOPTA) has never been used for intra-articular applications. Our aim was to test in vitro different concentrations of Gd-BOPTA to be potentially used to perform MRA. Methods Gd-BOPTA was diluted in saline (NaCl 0.9%) to achieve different concentrations (4 mmol/l; 2 mmol/l; 1 mmol/l; 0.67 mmol/l; 0.5 mmol/l). Six sets of five sterile pipes were prepared with 5 ml of each solution, five sets added with 0.5 ml of fresh synovial fluid. Two separate pipes were prepared with 5 ml of gadopentetate dimeg…

Validation of a Dutch diagnostic rule for gout without joint fluid analysis in patients hospitalized for acute monoarthritis

2020

Eolian and fluvial sedimentation in the southwestern Sinai Mountains, Egypt: a record of flash floods during the late Pleistocene

2012

Wadis emerging from the southwestern Sinai Mountains (Egypt) westwards to the Gulf of Suez are filled by >40 m thick late Pleistocene sediments, which have been subsequently incised to bedrock after the Last Glacial Maximum (LGM). Sedimentation and erosion resulted from changes in the basin's hydrological conditions caused by climate variations. Sediment characteristics indicate distinct processes ranging from high to low energy flow regimes. Airborne material is important as a sediment source. The fills are associated with alluvial fans at wadi mouths at the mountain fronts. Each alluvial fan is associated and physically correlated with the respective sediment fill in its contributi…

Simple Solution for Single Final Vial Filling of Ga-68 Radiopharmaceuticals in One Hot Cell Isolator at Small-Scale Radiopharmacy Laboratories under …

2020

A simple solution for fulfilling biosafety and national drug agency demands of radiation and biosafety during Ga-68 radionuclide containing radiopharmaceutical production (RP) by small scale laboratories has been demonstrated based on a novel sterile seal concept of multi-layer bag system prototype. These mid-and inner enclosures of the prototype with vial inside were sterilized by 50 kGy of gamma radiation. The microbial safety validation based on two-week testing confirmed successful sterilization of the sealing bags with vails. The analysis of physicochemical properties, namely mechanical properties, gel fraction studies revealed that sterilization did not cause any undesired changes in …

Factores asociados a los accidentes de motocicleta en Barcelona, España

2019

espanolResumen: Este estudio analizo los accidentes de motocicleta y ciclomotor en Barcelona (Espana). 53.190 informes de conductores de motocicleta y ciclomotor involucrados en accidentes entre los anos 2006 y 2011 fueron extraidos de la base de datos de accidentes con victimas de la Direccion General de Trafico. Estos datos fueron analizados en terminos de sexo, grupos de edad, motivo del desplazamiento, dia de la semana, infracciones de velocidad, uso del casco y lesividad, con el objetivo de estudiar las caracteristicas de los accidentes de motocicleta y ciclomotor en Barcelona y evaluar las diferencias entre conductores varones y mujeres en estos accidentes. La gravedad de los accident…

Urban growth (1956-2012) and soil sealing in the metropolitan area of Valencia (Eastern Spain)

2019

[EN] The aim of this study is to understand the urban growth dynamics from the mid-1950s to 2012 in the Metropolitan Area of Valencia, eastern Spain, and its impact on soils. The study area is a very interesting example of the many changes in land use and land cover in the landscape of Mediterranean alluvial plains. The analysis of urban growth was based on photo interpretation of aerial photographs and GIS based methodology. At a detailed scale (1:10,000), results show that there has been a highly dynamic process produced by the extent of land developed as urban area. In 1956 only 3,441 hectares (9.3% of the overall study area) were occupied by urban use. In 2012 the total sealed surface w…

The MIS 5 palaeoenvironmental record in the SE Mediterranean coast of the Iberian Peninsula (Río Antas, Almería, Spain)

2015

Se realiza un estudio detallado del episodio cálido MIS 5 en la zona sureste de la Península Ibérica. Se realiza la reconstrucción paleoambiental a partir del estudio polínico y biomarcadores de un sondeo perforado en la costa de Almería. La cronología se estableció a partir del método de racemizaciónd e aminoácidos.Landwards of a MIS5 bar, a borehole core (SRA) was analyzed to establish the relationship between the lagoonal record and the raised beach deposits in the surroundings of the Antas river mouth and to reconstruct the Pleistocene palaeoenvironmental evolution 5 of the southern Mediterranean coast of the Iberian Peninsula. 63 samples were recovered for amino acid racemization datin…

Multi proxy analysis for reconstructing the late Holocene evolution of a Mediterranean Coastal Lagoon: Environmental variables within foraminiferal a…

2020

Abstract This study reconstructs the evolution of foraminiferal assemblages and the environmental variables (type of substrate, content in calcium carbonate and content in organic matter) in the Valencia lagoon (western Mediterranean) in response to changes in the late Holocene. In this area of low tidal range, several multiproxy analyses were carried out to determine which environmental variables influence the distribution of the fossil assemblage, and its association with global, regional or local climatic phenomena. The statistical results show that in environments with higher exposure to marine conditions, the calcium carbonate content is the dominant factor, whereas in more restricted …