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showing 10 items of 5786 documents

Association between lower extremity muscular strength and acute knee injuries in young team‐sports athletes

2020

The purpose of this study was to investigate LE muscular strength variables as potential risk factors for all and non‐contact acute knee and ACL injuries in young athletes. A total of 188 young (≤21) male and 174 female basketball and floorball players participated in LE muscular strength tests and were followed up to three years. The strength test battery consisted of 1RM leg press, maximal concentric isokinetic (60°/s) quadriceps and hamstrings and maximal isometric hip abductor strength. The outcomes were a new acute knee or ACL injury and a new acute non‐contact knee or ACL injury. A total of 51 (17 in males and 34 in females) new acute knee injuries registered and 17 (one in males and …

musculoskeletal diseasesmedicine.medical_specialtybiologyTeam sportbusiness.industryAthletesinjurypolvetligament Injury riskriskitekijätmusculoskeletal systembiology.organism_classificationPhysical strengthmusculoskeletal systemPeer reviewPhysical therapyMedicinevammatbusinessKnee injuriesAssociation (psychology)human activitieslihasvoimaurheilijat
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2020

The occupation of dental assistants (DAs) involves many health risks of the musculoskeletal system due to static and prolonged work, which can lead to musculoskeletal disorders (MSDs). The aim of the study was to investigate the prevalence of MSDs in DAs in Germany. Methods: For this purpose, an online questionnaire analyzed 406 (401 female participants and 5 male participants, 401w/5m) DAs. It was based on the Nordic Questionnaire (lifetime, 12-month, and seven-day MSDs’ prevalence separated into neck, shoulder, elbow, wrist, upper back, lower back, hip, knee, and ankle), and occupational and sociodemographic questions as well as questions about specific medical conditions. Results: 98.5% …

musculoskeletal diseasesmedicine.medical_specialtybusiness.industryHealth Toxicology and MutagenesisDental AssistantElbowPublic Health Environmental and Occupational HealthHuman factors and ergonomics030206 dentistryComputer-assisted web interviewingDental educationWrist03 medical and health sciences0302 clinical medicinemedicine.anatomical_structurePhysical therapyMedicineBody region030212 general & internal medicineAnklebusinesshuman activitiesInternational Journal of Environmental Research and Public Health
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Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs).

2013

Abstract Inhibitors of Apoptosis (IAPs) are a family of proteins with various biological functions including regulation of innate immunity and inflammation, cell proliferation, cell migration and apoptosis. They are characterized by the presence of at least one N-terminal baculoviral IAP repeat (BIR) domain involved in protein-protein interaction. Most of them also contain a C-terminal RING domain conferring an E3-ubiquitin ligase activity. In drosophila, IAPs are essential to ensure cell survival, preventing the uncontrolled activation of the apoptotic protease caspases. In mammals, IAPs can also regulate apoptosis through controlling caspase activity and caspase-activating platform format…

musculoskeletal diseasesvirusesReviewIAP antagonistsXIAPLigase activityDIAP1lcsh:QH301-705.5CaspaseInhibitor of apoptosis domainbiologyCell growthapoptosisapoptosomeGeneral MedicineCell biologyXIAPbody regionslcsh:Biology (General)caspasesApoptosisRIPcIAPsbiology.proteinKeywordsDIAP1Baculoviral IAP repeat-containing protein 3Apoptosomebiological phenomena cell phenomena and immunityCells
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Intra-Articular Injection of Botulinum Toxin for the Treatment of Knee Osteoarthritis: A Systematic Review of Randomized Controlled Trials

2023

The purpose of the present paper was to review the available evidence on intra-articular botulinum toxin (BTX) injection in the treatment of knee osteoarthritis and to compare it to other conservative treatment options. A systematic review of the literature was performed on the PubMed, Scopus, Cochrane Library, Web of Science, Pedro and Research Gate databases with the following inclusion criteria: (1) randomized controlled trials (RCTs), (2) written in the English language, and (3) published on indexed journals in the last 20 years (2001–2021) dealing with the use of BTX intra-articular injection for the treatment of knee OA. The risk of bias was assessed using the Cochrane Risk of Bias to…

musculoskeletalSettore MED/34 - Medicina Fisica E RiabilitativaOrganic Chemistryintra-articularGeneral MedicineCatalysisComputer Science ApplicationsarthritiInorganic Chemistrysystematic reviewbotulinumtendinopathyPhysical and Theoretical ChemistryMolecular BiologySpectroscopyInternational Journal of Molecular Sciences
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Music Piracy Neutralization and the Youth of the 2010's

2014

In this qualitative research, music piracy among the youth was studied by applying Sykes’ and Matza’s neutralization theory. The key objective of the study was to find out how youths view music piracy, and how they give accounts for it using techniques of neutralization. According to the conducted semi-structured interviews, youths do acknowledge the ethical and economic problems of music piracy. However, piracy is still exercised, and in order to justify this, multiple neutralization techniques are used. The most characteristic of the employed techniques was “claim of normalcy”, with “denial of victim” and “justification by comparison” also appearing frequently. In order to prevent piracy,…

music piracyinterviewnuoruusComputingMilieux_LEGALASPECTSOFCOMPUTINGneutralization theory
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Systematic Use of Song and Music in Dementia Care: Health Care Providers’ Experiences

2020

Background and Aim Using song and music in a systematic way in residential dementia care may have several positive impacts on the patients, as well as the care providers. The aim of this study was to explore how health care providers experienced taking responsibility for conducting a song and music program in dementia care in nursing homes. Methods An explorative, qualitative study design was used. Focus groups were formed by 17 health care providers from 3 different nursing homes. These providers had experience implementing and using the “Gjenklang” (“reverberation”) song and music program especially developed for people with dementia. Focus group interviews were transcribed verbatim, and …

music programfocus group interviewsVDP::Medisinske Fag: 700::Helsefag: 800music therapyqualitativenursing homeshumanitiesOriginal Researchdementia
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Musical Self-Concept - Presentation of a Multi-Dimensional Model and Its Empirical Analyses

2009

Research on the specific domain of musical self-concept was so far exclusively concerned with musically active subjects (such as performers, music teachers, students, or singing children). In contrast, the starting base of the presented research is that music is a distinct aspect in everyone’s life and personality and that therefore musical self-concept is general and includes a number of domain besides achievement. The presented multi-dimensional model includes (i) non-academic and (ii) dimensions of musical ability. The first section entails representations with regards to “who I am” in music, such as emotional, social, physical, cognitive and spiritual notions, while section two addresse…

musical developmentMusical self-conceptmusical self-concept scalessemi-structured interviewmusical biographyqualitative content analysesmusical experience
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Management of Statin Intolerance in 2018: Still More Questions Than Answers.

2018

Statin therapy is generally well tolerated and very effective in the prevention and treatment of cardiovascular disease, regardless of cholesterol levels; however, it can be associated with various adverse events (myalgia, myopathy, rhabdomyolysis, and diabetes mellitus, among others). Patients frequently discontinue statin therapy without medical advice because of perceived side effects and consequently increase their risk for cardiovascular events. In patients with statin intolerance, it may be advisable to change the dose, switch to a different statin, or try an alternate-day regimen. If intolerance is associated with all statins—even at the lowest dose—non-statin drugs and certain nutra…

myalgiamedicine.medical_specialtyStatinDrug-Related Side Effects and Adverse Reactionsmedicine.drug_classDiseaseReview Article030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicinePharmacotherapyMedical adviceDiabetes mellitusCardiovascular DiseasemedicineHumansPharmacology (medical)030212 general & internal medicinecardiovascular diseasesAdverse effectIntensive care medicineDietary SupplementHypolipidemic AgentsHypolipidemic Agentbusiness.industrynutritional and metabolic diseasesDisease ManagementGeneral MedicineCholesterol LDLmedicine.diseaseRegimenCardiovascular DiseasesDietary Supplementslipids (amino acids peptides and proteins)Hydroxymethylglutaryl-CoA Reductase Inhibitormedicine.symptomHydroxymethylglutaryl-CoA Reductase InhibitorsCardiology and Cardiovascular MedicinebusinessDrug-Related Side Effects and Adverse ReactionHumanAmerican journal of cardiovascular drugs : drugs, devices, and other interventions
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Modeling of Myotonic Dystrophy Cardiac Phenotypes in

2018

After respiratory distress, cardiac dysfunction is the second most common cause of fatality associated with the myotonic dystrophy (DM) disease. Despite the prevalance of heart failure in DM, physiopathological studies on heart symptoms have been relatively scarce because few murine models faithfully reproduce the cardiac disease. Consequently, only a small number of candidate compounds have been evaluated in this specific phenotype. To help cover this gap Drosophila combines the amenability of its invertebrate genetics with the possibility of quickly acquiring physiological parameters suitable for meaningful comparisons with vertebrate animal models and humans. Here we review available des…

myotonic dystrophyNeurologycardiac dysfunctionCTG expansionCCTG expansionMini ReviewDrosophila disease modelMuscleblinddrugsFrontiers in neurology
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RIED. Revista iberoamericana de educación a distancia

2015

Los Massive Online Open Courses (MOOC) son una modalidad de formación virtual que está ya presente en el panorama educativo actual y que responde a una concepción determinada de e-learning. Las universidades están integrando como parte de su oferta formativa este tipo de formación o, al menos, se está debatiendo si se integra o no. Ante esto, se hace necesario calibrar cuáles deben ser sus características con el fin de configurar un tipo de formación virtual de calidad. Se considera que son necesarios instrumentos que avalen la calidad de los MOOC desde diferentes perspectivas, en este caso la pedagógica, ya que de ello dependerá el éxito y la consolidación de este tipo de e-learning. El ob…

método multimediaComputer scienceEducaciónmedia_common.quotation_subjectVarimax rotationValidityMOOCInvestigación en educación a distanciaFormative assessmentConsistency (negotiation)enseñanza a distanciaDidáctica y Organización EscolarMathematics educationVirtual trainingPedagogical practiceQuality (business)EvaluationAdaptation (computer science)Online educationeducación abiertaGeneral Environmental Sciencemedia_commonModality (human–computer interaction)business.industryEducación en líneaprograma de estudiosevaluaciónReview of distance education researchPráctica pedagógicaGeneral Earth and Planetary Sciencescalidad de la educaciónArtificial intelligenceEducacióbusinessRIED. Revista Iberoamericana de Educación a Distancia
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