Search results for "View"

showing 10 items of 5786 documents

Antioxidant Therapies and Oxidative Stress in Friedreich´s Ataxia: The Right Path or Just a Diversion?

2020

Friedreich's ataxia is the commonest autosomal recessive ataxia among population of European descent. Despite the huge advances performed in the last decades, a cure still remains elusive. One of the most studied hallmarks of the disease is the increased production of oxidative stress markers in patients and models. This feature has been the motivation to develop treatments that aim to counteract such boost of free radicals and to enhance the production of antioxidant defenses. In this work, we present and critically review those 'antioxidant' drugs that went beyond the disease's models and were approved for its application in clinical trials. The evaluation of these trials highlights some …

reactive oxygen speciesFriedreich’s ataxia; clinical trials; oxidative stress; antioxidant therapies; reactive oxygenspecies; scavengers; antioxidant response; mitochondrial metabolism; ferroptosisclinical trialsmitochondrial metabolismantioxidant responseEstrès oxidatiulcsh:RM1-950Friedreich’s ataxiaReviewFriedreich´s ataxia590 Tiere (Zoologie)Antioxidantsferroptosisscavengerslcsh:Therapeutics. Pharmacology570 Biowissenschaften Biologieddc:590oxidative stressantioxidant therapiesddc:570Antioxidants
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Development of silent reading fluency and reading comprehension across grades 1 to 9 : unidirectional or bidirectional effects between the two skills?

2022

Purpose This study examines the developmental interplay between silent reading fluency and reading comprehension from Grade 1 to Grade 9 (age 7 to 15) in a large Finnish sample (N = 2,518). Of particular interest was whether the associations are bidirectional or unidirectional. Methods Children’s silent reading fluency and reading comprehension skills were assessed using group-administered tests, at seven time points, in Grades 1, 2, 3, 4, 6, 7, and 9. A random intercept cross-lagged panel model with latent factors was used to identify between- and within-person associations between silent reading fluency and reading comprehension. The use of latent factors allowed for the controlling of me…

reading fluencyluetun ymmärtäminennuoretkielellinen kehityshiljainen lukemineninteraction modelssujuvuusbidirectional effectslapset (ikäryhmät)unidirectional effectssimple view of readingreading comprehensionlukeminen
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Albanian students’ motives for preferring certain real-life situations for learning mathematics

2011

This article reports on a qualitative investigation of Albanian students’ motives for preferring certain real-life situations to be used in school mathematics, and possible connections of these motives to characteristics and issues within Albanian society. It is based on realistic interviews with students from Grades 8 and 9 in a school in the district of Shkodra in northern Albania. Interviews were conducted after students experienced five teaching units which dealt with mathematics embedded in real-life situations. Results are expressed in terms of contextmechanism-outcome configurations as proposed by critical realist theory. Most of the resultsare supported by those from a previous quan…

realist paradigmlcsh:MathematicsGeneral MathematicsReal-life situationsrealistic interviewslcsh:QA1-939students' preferencesEducationCritical realistPedagogyComputingMilieux_COMPUTERSANDEDUCATIONMathematics educationPsychologyCommunity developmentRecreationPythagoras
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How and Why ‘Theory’ Is Often Misunderstood in Information Systems Literature

2019

IS theory accounts have increased our understanding of scientific theories. However, many influential theory accounts in Information Systems (IS) are influenced by the Received View of scientific theory (RV), which flourished in the philosophy of science around 1930-1969. The RV has been widely rejected in the philosophy of science, as the theory ignored much of the actual scientific context, and it mischaracterized several important characteristics of scientific research and theories. Although RV ideas were crafted for philosophers’ philosophical purposes, and not for scientists’ use, several IS scholars seem to believe that some of the RV theses represent actual (good or strong) scientifi…

received viewlogical empiricismtieteenfilosofialogical reconstructionstieteenteorialooginen empirismitheorytietojärjestelmät
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Clinical assessment and comparison of ACL reconstruction using synthetic graft (Neoligaments versus FiberTape).

2021

Background Due to the low potential for primary biological healing of the anterior cruciate ligament (ACL), the most popular approach is currently reconstruction using a graft. Recent research indicates that the technique of strengthening a damaged ligament with synthetic tapes (internal bracing) may be an alternative to reconstructive treatment, especially in cases of partial ACL damage. Objectives To compare and evaluate the possibility of using a synthetic graft (Neoligaments or FiberTape) to treat partial lesions of the ACL. Material and methods This was a retrospective cohort study. Selected from a pool of 128 patients undergoing primary unilateral intra-articular ACL reconstruction du…

reconstructionKnee JointAnterior cruciate ligamentMedicine (miscellaneous)primary repairGroup comparisonKnee JointLachman testGeneral Biochemistry Genetics and Molecular BiologyInternal MedicinemedicineHumansPharmacology (medical)internal bracingAnterior Cruciate LigamentGenetics (clinical)Retrospective StudiesOrthodonticsAnterior Cruciate Ligament Reconstructionbusiness.industryAnterior Cruciate Ligament InjuriesRetrospective cohort studySynthetic graftmusculoskeletal systemathletesmedicine.anatomical_structureTreatment OutcomeReviews and References (medical)LigamentbusinessRange of motionhuman activitiesAdvances in clinical and experimental medicine : official organ Wroclaw Medical University
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Students’ Experiences of Reflective Writing as a Tool for Learning in Physiotherapy Education

2015

The purpose of this study was to examine physiotherapy students’ experiences of reflective writing. The students (n = 32) were asked to video record their practical activities at school and at workplaces, and to write reflective journals on their experiences. The research data about students’ experiences of reflective writing were collected by interviewing the students. The data were analyzed phenomenographically. The findings revealed four qualitatively different experiences of reflective writing: 1) writing as a useless task; 2) writing as a tool for deepening understanding; 3) writing as a tool for self-reflection; and 4) writing as a tool for professional development. These categories d…

reflektiivisyysopiskelijatInterviewComputer sciencemedia_common.quotation_subjectProfessional developmentReflective writingApplied linguisticsfysioterapiaTask (project management)Professional learning communityPedagogyComputingMilieux_COMPUTERSANDEDUCATIONMathematics educationFunction (engineering)Reflection (computer graphics)kirjoittaminenmedia_common
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FRP reinforcement for concrete structures: state-of-the-art review of application and design

2014

Fiber reinforced polymers (FRPs) are considered to be a promising alternative to steel reinforcement, especially in concrete structures subjected to an aggressive environment or to the effects of electromagnetic fields. Although attempts to develop effective reinforcement have been followed, the application of FRPs remains limited by the solution to simple structural problems that mainly appear due to the absence of design codes, significant variation in the material properties of FRP composites and limited knowledge gained by engineers as regards the application aspects of FRP composites and structural mechanics of concrete elements reinforced with FRPs. To fill the latter gap, the current…

reinforcementMaterials sciencebusiness.industryManufacturing processStructural mechanicsStructural engineeringState of the art reviewfiber reinforced polymersFibre-reinforced plasticEngineering (General). Civil engineering (General)Frp reinforcementFRP barsTA1-2040businessMaterial propertiesReinforcementmaterial propertiesapplicationEngineering Structures and Technologies
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Surrogacy relationships: a critical interpretative review

2020

Abstract Based on a critical interpretative review of existing qualitative research investigating accounts of ‘lived experience’ of surrogates and intended parents from a relational perspective, this article proposes a typology of surrogacy arrangements. The review is based on the analysis of 39 articles, which belong to a range of different disciplines (mostly sociology, social psychology, anthropology, ethnology, and gender studies). The number of interviews in each study range from as few as seven to over one hundred. Countries covered include Australia, Canada, Greece, India, Iran, Israel, Italy, Mexico, Norway, Russia, Sweden, UK, Ukraine, and the USA. Most studies focus only on surrog…

relational ethicsTypologySocial psychology (sociology)surrogacyInternational Cooperationsurrogate motherhoodlcsh:Medicine030209 endocrinology & metabolismContext (language use)Personal SatisfactionReview ArticleGlobal Healthethnographyqualitative interviews03 medical and health sciences0302 clinical medicinePregnancyOrder (exchange)EthnographyHumansMedicineInterpersonal RelationsReview ArticlesQualitative ResearchSurrogate MothersCultural Characteristics030219 obstetrics & reproductive medicinebusiness.industryHealth Policylcsh:Rassisted reproductionreproductive justiceGender studiesGeneral MedicineBioethicsReproductive justicecritical interpretative reviewFemalebusinessqualitative methodsQualitative researchUpsala Journal of Medical Sciences
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Filozoficzne koncepcje światopoglądu religijnego jako inspiracje dla współczesnych teorii religii

2015

Celem artykułu jest przedstawienie wybranych filozoficznych koncepcji światopoglądu religijnego jako źródeł inspiracji, jak również obiecujących rozwiązań konkretnych problemów współczesnych teorii religii. Dokonane w artykule zestawienie filozoficznych koncepcji światopoglądu religijnego takich myślicieli jak: Bergsona, Schelera, czy Diltheya z wybranymi współczesnymi teoriami religii z zakresu psychologii ewolucyjnej przemawia za potrzebą udziału filozofii w trwających interdyscyplinarnych badaniach nad fenomenem religii.

religiaSchelerreligionświatopogląd religijnyteoria światopoglądówDiltheyScott.religious worldviewtheory of worldviewsScottBergsonDennettTekstoteka Filozoficzna
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Engaging with feedback: How do students remediate errors on their weekly quiz

2018

International audience; Maths for Business is a first-year mathematics module for approximately 500 non-mathematics specialists. It has continuous assessment consisting of ten weekly quizzes, worth 40% of the final mark. In 2016/17, students who did not receive the maximum five marks on their weekly quiz were offered the opportunity to resubmit their quiz, with correction(s) and an explanation of their error(s), for one additional mark. We refer to this process as ‘remediation'. In this paper, we examine how students remediate their errors in order to identify features of a ‘good' remediation. These features are identification, description, and correction of errors. By analysing a subset of…

remediation of errorsstudents' practices at university level.[SHS.EDU]Humanities and Social Sciences/Education[MATH.MATH-HO]Mathematics [math]/History and Overview [math.HO][SHS.EDU] Humanities and Social Sciences/Education[MATH.MATH-HO] Mathematics [math]/History and Overview [math.HO]feedbackassessment practices in university mathematics education
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