Search results for "Visual acuity"

Tocilizumab as first treatment option in optic neuropathy secondary to Graves' orbitopathy.

2018

Dysthyroid optic neuropathy (DON) is one of the complications that can affect Graves' orbitopathy (GO) patients. Its prevalence is estimated at less than 5%. It is usually treated with intravenous steroids, radiotherapy or orbital decompression. Tocilizumab has been proposed as a treatment option in cases of GO refractory to steroid treatment, with good clinical results. Our aim is to report the case of a patient with optic neuropathy secondary to GO treated with tocilizumab as primary treatment option.

Detection of behavioral alterations and learning deficits in mice lacking synaptophysin.

2009

The integral membrane protein synaptophysin is one of the most abundant polypeptide components of synaptic vesicles. It is not essential for neurotransmission despite its abundance but is believed to modulate the efficiency of the synaptic vesicle cycle. Detailed behavioral analyses were therefore performed on synaptophysin knockout mice to test whether synaptophysin affects higher brain functions. We find that these animals are more exploratory than their wild type counterparts examining novel objects more closely and intensely in an enriched open field arena. We also detect impairments in learning and memory, most notably reduced object novelty recognition and reduced spatial learning. Th…

Accommodation-related changes in monochromatic aberrations of the human eye as a function of age.

2008

PURPOSE. To investigate the relationship between accommodation and the optical aberrations of the whole human eye, as a function of age. METHODS. Sixty healthy subjects with spherical ametropia in the range 3 D, astigmatism less than 1 D, corrected visual acuity of 20/18 or better, and normal findings in an ophthalmic examination were enrolled. Subjects were divided into four groups, with age ranges of 19 to 29, 30 to 39, 40 to 49, and 50 to 60 years. Monochromatic optical aberrations and pupil size were measured with a Hartmann-Shack wavefront sensor under monocular viewing conditions, without pharmacological dilation or cycloplegia. Stimulus vergences were in the range of 0 to 5 D, with a…

Occult non-metallic intraocular foreign body causing recurrent anterior uveitis

2015

Purpose To describe the case of textile worker with recurrent anterior uveitis following the traumatic penetration of nylon thread into the anterior segment of the eye. Methods Examination by slit-lamp of the affected eye B-scan ultrasonography during the inflammatory episode and after the resolution of the uveitis. Visual Acuity Measurement during the inflammatory episode and after the resolution of the uveitis. Results The use of topical therapy together with antibiotic systemic therapy led to the regression of the inflammatory symptoms (intense epibulbar and tarsal hyperemia with perikeratic reaction, corneal sub-oedema with some folds in the Descemet's membrane, Tyndall 2+ and a layer o…

Visual Acuity in Myopes with Standard and Reversed Contrast Optotypes

2017

Abstract The aim of this study was to assess the visual acuity of myopes with standard and reversed contrast optotypes and to determine how the visual acuity of myopes is affected by optical defocus and the type of optical correction, either contact lenses or spectacles. Twenty-three myopic subjects (18 and 23 years old) with uncorrected vision had their visual acuity assessed with both standard and reversed contrast optotypes. The study also included 10 myopes with contact lens as well as habitual spectacle correction. The visual acuity for myopes with uncorrected vision was better with reversed than standard contrast optotypes. Better reversed contrast than standard contrast visual acuity…

High myopic patients with and without foveoschisis: morphological and functional characteristics.

2020

Purpose: Myopic foveoschisis (MF) is characterized by the splitting of the retinal layers in the fovea of patients with high myopia (HM). MF may progress into foveal detachment or macular hole formation with consequent loss of central vision. The aim of this study is to investigate morphological and functional changes of the macular region in myopic subjects with and without foveoschisis. Design: Observational, cross-sectional, comparative study. Methods: Forty-eight patients with HM and 24 healthy controls were evaluated by spectral domain-optical coherence tomography (SD-OCT), multifocal electroretinography (mfERG) and microperimetry (MP-1) tests to assess macular thickness, functionality…

Effect of even and odd-order aberrations on the accommodation response

2017

Aim To investigate the potential effect that odd and even-order monochromatic aberrations may have on the accommodation response of the human eye. Methods Eight healthy subjects with astigmatism below 1 D, best corrected visual acuity 20/20 or better and normal findings in an ophthalmic examination were enrolled. An adaptive optics system was used in order to measure the accommodation response of the subjects' eyes under different conditions: with the natural aberrations being present, and with the odd and even-order aberrations being corrected. Three measurements of accommodation response were monocularly acquired at accommodation demands ranging from 0 to 4 D (0.5 D step). Results The acc…

Visual acuity changes in presbyopic patients fitted with 3 multifocal contact lenses

2012

Angioma retiniano como síndrome mascarada de tumor del nervio óptico en la enfermedad de Von Hippel-Lindau

2006

espanolCaso clinico: Varon de 35 anos con antecedentes familiares de enfermedad de von Hippel-Lindau (VHL) diagnosticado de dos hemangiomas retinianos en ojo derecho (OD) y uno en ojo izquierdo. Las lesiones se trataron con crioterapia en OD y laserterapia en OI. A pesar de una aparente buena evolucion de las lesiones retinianas hubo una progresiva disminucion de la AV. Se realizo RM donde se evidencio lesiones tumorales del nervio optico (NO) bilaterales compatibles con glioma, meningioma o hemangioblastoma. Actualmente: AV (OD): movimiento de manos y AV(OI): 0,6. Discusion: La presencia de los hemangiomas retinianos en este paciente hizo retrasar el diagnostico de un tumor en el NO, infre…

Power profiles in multifocal contact lenses with variable multifocal zone

2016

BACKGROUND The power profile of multifocal contact lenses has been demonstrated to report important information that could be used during the fitting process. The aim of this work is to describe the power profile of a recent set of gas permeable multifocal contact lenses as a function of the pupil radius. METHODS The measured multifocal contact lenses have a centre-distance design, and are available with five distance-vision diameters (XS, S, M, L and XL) and two different additions: Type A (up to +2.00 D) and Type B (up to +2.50 D). The optical device NIMO TR1504 (Lambda-X, Nivelles, Belgium) was used to obtain the power profile measurements. The optical lens power distribution as a functi…