Search results for "Vulvovaginitis"

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Mixed vaginal infections of Balb/c mice with low virulent herpes simplex type 1 strains result in restoration of virulence properties: vaginitis/vulv…

1997

Vaginal infections of BALB/c Ann mice with herpes simplex virus type 1 (HSV-1) were studied. Mice were inoculated with virulent strains ANG path and 17 syn+ or low-virulent recombinant strains 27/III and 17-syn3 that differ from parental strains in their glycoprotein B (gB) gene sequences. When low-virulent strains were inoculated separately, no vaginitis/vulvitis was produced despite replication in the vagina. In contrast, after coinfection of mice with the two low-virulent strains, vaginitis/vulvitis was produced and virus could be recovered from the central nervous system (CNS). Two of the CNS isolates produced vaginitis/vulvitis, neuroinvasiveness and death of mice after vaginal infecti…

Microbiology (medical)Central Nervous SystemImmunologyMolecular Sequence DataVirulenceHerpesvirus 1 Humanmedicine.disease_causePolymerase Chain ReactionVirusBALB/cMicrobiologyMiceVaginal diseasemedicineImmunology and AllergyAnimalsAmino Acid SequenceEncephalomyelitisVaginitisRecombination GeneticMice Inbred BALB CbiologyGeneral MedicineSequence Analysis DNAmedicine.diseasebiology.organism_classificationVulvovaginitisVirologyHerpes simplex virusVulvitisCoinfectionFemalemedicine.symptomMedical microbiology and immunology

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